Differences in pharmacokinetics and ex vivo antioxidant activity following intravenous and oral administrations of emodin to rats

Journal of Pharmaceutical Sciences

Volumn 99, Issue 4, 2010, Pages 2185-2195

  Shia, Chi Sheng ^a   Hou, Yu Chi ^a   Tsai, Shang Yuan ^a   Huieh, Pei Hsun ^a   Leu, Yann Lii ^b   Chao, Pei Dawn Lee ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Emodin; Glucuronides; Metabolism; Pharmacokinetics; hydroxyemodin

Indexed keywords

2,2' AZOBIS(2 AMIDINOPROPANE HYDROCHLORIDE); ALKANE DERIVATIVE; ASCORBIC ACID; BETA GLUCURONIDASE; DRUG METABOLITE; EMODIN; EMODIN G; EMODIN GLUCURONIDE DERIVATIVE; GLUCURONIDE; OMEGA HYDROXYEMODIN; OMEGA HYDROXYEMODIN GLUCURONIDE DERIVATIVE; OMEGA HYDROXYEMODIN SULFATE DERIVATIVE; SULFATASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG HYDROLYSIS; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; RAT; SCAVENGING SYSTEM; STRUCTURE ACTIVITY RELATION;

EID: 77949839779     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21978     Document Type: Article

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