IgG particle formation during filling pump operation: A case study of heterogeneous nucleation on stainless steel nanoparticles

Journal of Pharmaceutical Sciences

Volumn 98, Issue 1, 2009, Pages 94-104

  Tyagi, Anil K ^a   Randolph, Theodore W ^b   Dong, Aichun ^c   Maloney, Kevin M ^d   Hitscherich Jr , Carl ^d   Carpenter, John F ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UCB 450   (United States)

^c UNIVERSITY OF NORTHERN COLORADO   (United States)

^d BIOGEN   (United States)

Author keywords

Aggregation; IgG; Particle formation; Stability; Steel nanosphere

Indexed keywords

IMMUNOGLOBULIN G; NANOPARTICLE; NANOSPHERE; SOLVENT; STAINLESS STEEL;

ARTICLE; CONTROLLED STUDY; DRUG FORMULATION; DRUG MANUFACTURE; DRUG SAFETY; FILTER; FILTRATION; FOREIGN BODY; PROTEIN AGGREGATION; PUMP; SPECTROSCOPY;

EID: 58149216346     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21419     Document Type: Article

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