Binding of herpes simplex virus type-1 virions leads to the induction of intracellular signalling in the absence of virus entry

PLoS ONE

Volumn 5, Issue 3, 2010, Pages

  MacLeod, Iain J ^a,b   Minson, Tony ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; STAT PROTEIN; VIRUS GLYCOPROTEIN; COMPLEMENTARY DNA;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; GENE EXPRESSION; GENE INDUCTION; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; VIRION; VIRUS ATTACHMENT; VIRUS CELL INTERACTION; ACTIVE TRANSPORT; ANIMAL; CERCOPITHECUS; DNA MICROARRAY; FIBROBLAST; GENE EXPRESSION PROFILING; METABOLISM; PHENOTYPE; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; VERO CELL;

HUMAN HERPESVIRUS 1;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CERCOPITHECUS AETHIOPS; DNA, COMPLEMENTARY; FIBROBLASTS; GENE EXPRESSION PROFILING; GENES, REPORTER; HERPESVIRUS 1, HUMAN; HUMANS; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENOTYPE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; VERO CELLS;

EID: 77949721978     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0009560     Document Type: Article

References (48)

1. Sciortino MT, Medici MA, Marino-Merlo F, Zaccaria D, Giuffré- Cuculletto M, et al. (2008) Involvement of gD/HVEM interaction in NFkB-dependent inhibition of apoptosis by HSV-1 gD. Biochem Pharmacol 76: 1522-32.
2. Heldwein EE, Krummenacher C (2008) Entry of herpesviruses into mammalian cells. Cell Mol Life Sci 65: 1653-1668.
3. Browne H (2009) The role of glycoprotein H in herpesvirus membrane fusion. Protein Pept Lett 16: 760-765.
4. Parry C, Bell S, Minson T, Browne H (2005) Herpes simplex virus type 1 glycoprotein H binds to alphavbeta3 integrins. J Gen Virol 86: 7-10.
5. Satoh T, Arii J, Suenaga T, Wang J, Kogure A, et al. (2008) PILRalpha is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B. Cell 132: 935-944.
6. Medici MA, Sciortino MT, Perri D, Amici C, Avitabile E, et al. (2003) Protection by Herpes Simplex Virus Glycoprotein D against Fas-mediated Apoptosis: ROLE OF NUCLEAR FACTOR {kappa}B. J Biol Chem 278: 36059-36067.
7. Patel A, Hanson J, McLean TI, Olgiate J, Hilton M, et al. (1998) Herpes Simplex Virus Type 1 Induction of Persistent NF-kB Nuclear Translocation Increases the Efficiency of Virus Replication*1. Virology 247: 212-222.
8. Amici C, Rossi A, Costanzo A, Ciafre S, Marinari B, et al. (2006) Herpes Simplex Virus Disrupts NF-{kappa}B Regulation by Blocking Its Recruitment on the I{kappa}B{alpha} Promoter and Directing the Factor on Viral Genes. J Biol Chem 281: 7110-7117.
9. Sciortino MT, Medici MA, Marino-Merlo F, Zaccaria D, Giuffrè M, et al. (2007) Signaling Pathway Used by HSV-1 to Induce NF-kB Activation. Annals of the New York Academy of Sciences 1096: 89-96.
10. Simmen KA, Singh J, Luukkonen BGM, Lopper M, Bittner A, et al. (2001) Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B. Proc Natl Acad Sci U S A 98: 7140-7145.
11. D'Addario M, Ahmad A, Morgan A, Menezes J (2000) Binding of the epstein-barr virus major envelope glycoprotein gp350 results in the upregulation of the TNF-α gene expression in monocytic cells via NF-kb involving PKC, PI3-K and tyrosine kinases1. Journal of molecular biology 298: 765-778.
12. D'Addario M, Libermann TA, Xu J, Ahmad A, Menezes J (2001) Epstein-Barr virus and its glycoprotein-350 upregulate IL-6 in human B-lymphocytes via CD21, involving activation of NF-kB and different signaling pathways1. Journal of molecular biology 308: 501-514.
13. Cai WH, Gu B, Person S (1988) Role of glycoprotein B of herpes simplex virus type 1 in viral entry and cell fusion. J Virol 62: 2596-604.
14. Forrester A, Farrell H, Wilkinson G, Kaye J, Davis-Poynter N, et al. (1992) Construction and properties of a mutant of herpes simplex virus type 1 with glycoprotein H coding sequences deleted. J Virol 66: 341-348.
15. Ligas MW, Johnson DC (1988) A herpes simplex virus mutant in which glycoprotein D sequences are replaced by beta-galactosidase sequences binds to but is unable to penetrate into cells. J Virol 62: 1486-94.
16. Roop C, Hutchinson L, Johnson DC (1993) A mutant herpes simplex virus type 1 unable to express glycoprotein L cannot enter cells, and its particles lack glycoprotein H. J Virol 67: 2285-97.
17. Naldinho-Souto R, Browne H, Minson T (2006) Herpes Simplex Virus Tegument Protein VP16 Is a Component of Primary Enveloped Virions. J Virol 80: 2582-2584.
18. Babic N, Rodger G, Arthur J, Minson AC (1999) A study of primary neuronal infection by mutants of herpes simplex virus type 1 lacking dispensable and nondispensable glycoproteins. J Gen Virol 80: 2403-2409.
19. Boursnell ME, Entwisle C, Blakeley D, Roberts C, Duncan IA, et al. (1997) A genetically inactivated herpes simplex virus type 2 (HSV-2) vaccine provides effective protection against primary and recurrent HSV-2 disease. J Infect Dis 175: 16-25.
20. Rodger G, Boname J, Bell S, Minson T (2001) Assembly and Organization of Glycoproteins B, C, D, and H in Herpes Simplex Virus Type 1 Particles Lacking Individual Glycoproteins: No Evidence for the Formation of a Complex of These Molecules. J Virol 75: 710-716.
21. Watson DH, Russell WC, Wildy P (1963) Electron microscopic particle counts on herpes virus using the phosphotungstate negative staining technique. Virology 19: 250-60.
22. Paludan SR, Mogensen SC (2001) Virus-Cell Interactions Regulating Induction of Tumor Necrosis Factor Alpha Production in Macrophages Infected with Herpes Simplex Virus. J Virol 75: 10170-10178.
23. Rozen S, Skaletsky H (2000) Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 132: 365-86.
24. Pfaffl MW (2001) A new mathematical model for relative quantification in realtime RT-PCR. Nucleic Acids Res 29: e45.
25. Minson AC, Hodgman TC, Digard P, Hancock DC, Bell SE, et al. (1986) An analysis of the biological properties of monoclonal antibodies against glycoprotein D of herpes simplex virus and identification of amino acid substitutions that confer resistance to neutralization. J Gen Virol 67 (Pt 6): 1001-1013.
26. McLean C, Buckmaster A, Hancock D, Buchan A, Fuller A, et al. (1982) Monoclonal antibodies to three non-glycosylated antigens of herpes simplex virus type 2. J Gen Virol 63: 297-305.
27. Browne H, Bell S, Minson T, Wilson DW (1996) An endoplasmic reticulumretained herpes simplex virus glycoprotein H is absent from secreted virions: evidence for reenvelopment during egress. J Virol 70: 4311-4316.
28. Thompson JF, Hayes LS, Lloyd DB (1991) Modulation of firefly luciferase stability and impact on studies of gene regulation. Gene 103: 171-177.
29. Ankel H, Westra DF, Welling-Wester S, Lebon P (1998) Induction of Interferonα by Glycoprotein D of Herpes Simplex Virus: A Possible Role of Chemokine Receptors. Virology 251: 317-326.
30. Preston CM, Harman AN, Nicholl MJ (2001) Activation of Interferon Response Factor-3 in Human Cells Infected with Herpes Simplex Virus Type 1 or Human Cytomegalovirus. J Virol 75: 8909-8916.
31. Laude H, Gelfi J, Lavenant L, Charley B (1992) Single amino acid changes in the viral glycoprotein M affect induction of alpha interferon by the coronavirus transmissible gastroenteritis virus. J Virol 66: 743-749.
32. Johnson RA, Wang X, Ma X, Huong S, Huang E (2001) Human Cytomegalovirus Up-Regulates the Phosphatidylinositol 3-Kinase (PI3-K) Pathway: Inhibition of PI3-K Activity Inhibits Viral Replication and Virus-Induced Signaling. J Virol 75: 6022-6032.
33. D'Addario M, Ahmad A, Morgan A, Menezes J (2000) Binding of the epstein-barr virus major envelope glycoprotein gp350 results in the upregulation of the TNF-[alpha] gene expression in monocytic cells via NF-[kappa]b involving PKC, PI3-K and tyrosine kinases. Journal of Molecular Biology 298: 765-778.
34. Gregory D, Hargett D, Holmes D, Money E, Bachenheimer SL (2004) Efficient replication by herpes simplex virus type 1 involves activation of the IkappaB kinase-IkappaB-p65 pathway. J Virol 78: 13582-13590.
35. Taddeo B, Esclatine A, Roizman B (2002) The patterns of accumulation of cellular RNAs in cells infected with a wild-type and a mutant herpes simplex virus 1 lacking the virion host shutoff gene. Proc Natl Acad Sci USA 99: 17031-17036.
36. Aubert M, Blaho JA (2003) Viral oncoapoptosis of human tumor cells. Gene Ther 10: 1437-1445.
37. Huang DC, Cory S, Strasser A (1997) Bcl-2, Bcl-XL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death. Oncogene 14: 405-14.
38. Cory S, Adams JM (2002) The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2: 647-56.
39. Collins SE, Noyce RS, Mossman KL (2004) Innate Cellular Response to Virus Particle Entry Requires IRF3 but Not Virus Replication. J Virol 78: 1706-1717.
40. Noyce RS, Collins SE, Mossman KL (2006) Identification of a Novel Pathway Essential for the Immediate-Early, Interferon-Independent Antiviral Response to Enveloped Virions. J Virol 80: 226-235.
41. Dang CV (1999) c-Myc Target Genes Involved in Cell Growth, Apoptosis, and Metabolism. Mol Cell Biol 19: 1-11.
42. Rosenwald IB, Rhoads DB, Callanan LD, Isselbacher KJ, Schmidt EV (1993) Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc. Proc Natl Acad Sci U S A 90: 6175-6178.
43. Coller HA, Grandori C, Tamayo P, Colbert T, Lander ES, et al. (2000) Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion. Proc Natl Acad Sci U S A 97: 3260-3265.
44. Beier R, Bürgin A, Kiermaier A, Fero M, Karsunky H, et al. (2000) Induction of cyclin E-cdk2 kinase activity, E2F-dependent transcription and cell growth by Myc are genetically separable events. EMBO J 19: 5813-5823.
45. Hossain A, Holt T, Ciacci-Zanella J, Jones C (1997) Analysis of cyclin-dependent kinase activity after herpes simplex virus type 2 infection. J Gen Virol 78: 3341-3348.
46. Schang LM, Phillips J, Schaffer PA (1998) Requirement for Cellular Cyclin-Dependent Kinases in Herpes Simplex Virus Replication and Transcription. J Virol 72: 5626-5637.
47. Advani SJ, Weichselbaum RR, Roizman B (2000) E2F Proteins Are Posttranslationally Modified Concomitantly with a Reduction in Nuclear Binding Activity in Cells Infected with Herpes Simplex Virus 1. J Virol 74: 7842-7850.
48. Honda K, Taniguchi T (2006) IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat Rev Immunol 6: 644-658.