Nox-4-dependent nuclear H2O2 drives DNA oxidation resulting in 8-OHdG as urinary biomarker and hemangioendothelioma formation

Antioxidants and Redox Signaling

Volumn 12, Issue 8, 2010, Pages 933-943

  Gordillo, Gayle ^a   Fang, Huiqing ^a   Park, Hana ^a   Roy, Sashwati ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; DEFEROXAMINE; GLYCOPROTEIN GP 91; HYDROGEN PEROXIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CARCINOGENESIS; CELL CYCLE REGULATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA MODIFICATION; ENDOTHELIUM CELL; FEMALE; HEMANGIOENDOTHELIOMA; IRON CHELATION; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TUMOR GROWTH;

ANIMALS; BIOLOGICAL MARKERS; CELL NUCLEUS; CELLS, CULTURED; CHEMOKINE CCL2; DEOXYGUANOSINE; DNA; ENDOTHELIAL CELLS; FEMALE; HEMANGIOENDOTHELIOMA; HUMANS; HYDROGEN PEROXIDE; MICE; NADPH OXIDASE; OXIDANTS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RNA, SMALL INTERFERING;

MURINAE; MUS;

EID: 77949643542     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2009.2917     Document Type: Article

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