Novel synthetic gluco-disaccharide RSCL-0409 - A lipopolysaccharide-induced Toll-like receptor-mediated signalling antagonist

FEBS Journal

Volumn 277, Issue 7, 2010, Pages 1639-1652

  Kalluri, Mani D ^a   Datla, Praneel ^b   Bellary, Akshaya ^a   Basha, Khalander ^a   Sharma, Ashwani ^a   Sharma, Anuradha ^a   Singh, Shiva ^a   Upadhyay, Shakti ^b   Rajagopal, Vikram ^a  

^a RELIANCE LIFE SCIENCES PVT LTD   (India)

^b EID Parry India Ltd   (India)

Author keywords

Inflammation; Lipopolysaccharide; Monocytes; NF B; TLR signalling; Tumour necrosis factor

Indexed keywords

4 O CHLOROACETYL 2,3 DI O ACETYL O LEVULINOYL BETA DEXTRO GLUCOPYRANOSYL (1 3) 1 O (4 METHOXYPHENYL) 2 DEOXY 2 N TRICHLOROACETYL 4,6 O BENZYLIDENE ALPHA DEXTRO GLUCOPYRANOSIDE; CYCLOOXYGENASE 2; GLUCOPYRANOSIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MESSENGER RNA; RSCL 0409; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DRUG STRUCTURE; FEMALE; HUMAN; HUMAN TISSUE; INFLAMMATION; MONOCYTE; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; DISACCHARIDES; FEMALE; HUMANS; INFLAMMATION; LEUKOCYTES, MONONUCLEAR; LIGANDS; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED BALB C; MODELS, BIOLOGICAL; NF-KAPPA B; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

MURINAE;

EID: 77949593228     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2010.07589.x     Document Type: Article

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