Particulate matter inhalation exacerbates cardiopulmonary injury in a rat model of isoproterenol-induced cardiomyopathy

Inhalation Toxicology

Volumn 22, Issue 5, 2010, Pages 355-368

  Carll, Alex P ^a   Haykal Coates, Najwa ^b   Winsett, Darrell W ^b   Rowan III, William H ^c   Hazari, Mehdi S ^b   Ledbetter, Allen D ^b   Nyska, Abraham ^d   Cascio, Wayne E ^e   Watkinson, William P ^b   Costa, Daniel L ^b   Farraj, Aimen K ^b  

^a IL   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c ITT CORPORATION   (United States)

^d TEL AVIV UNIVERSITY   (Israel)

^e EAST CAROLINA UNIVERSITY   (United States)

Author keywords

Air pollution; Arrhythmia; Cardiomyopathy; Heart failure; Heart rate variability; Isoproterenol

Indexed keywords

BIOLOGICAL MARKER; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; ISOPRENALINE; LACTATE DEHYDROGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY MASS; BODY TEMPERATURE; BRADYCARDIA; CARDIOMYOPATHY; CARDIOPULMONARY FUNCTION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE EXACERBATION; ELECTROCARDIOGRAPHY; HEART HEMODYNAMICS; HEART MUSCLE CONTRACTILITY; HEART RATE; HEART RATE VARIABILITY; HISTOPATHOLOGY; HYPOTENSION; INHALATION; LUNG INJURY; LUNG LAVAGE; LUNG VENTILATION; MALE; NONHUMAN; PARASYMPATHETIC TONE; PARTICULATE MATTER; PRIORITY JOURNAL; PULSE PRESSURE; RAT; SYSTOLIC BLOOD PRESSURE; TACHYCARDIA;

ADRENERGIC BETA-AGONISTS; AIR POLLUTANTS; ANIMALS; CARDIOMYOPATHIES; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; HEART; HEART FAILURE; HEMODYNAMICS; INHALATION EXPOSURE; INJECTIONS, SUBCUTANEOUS; ISOPROTERENOL; L-LACTATE DEHYDROGENASE; LIPOPROTEINS, HDL; LUNG; MALE; MYOCARDIUM; ORGAN SIZE; PARTICULATE MATTER; RATS; RATS, INBRED SHR; TELEMETRY;

RATTUS;

EID: 77949543732     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.3109/08958370903365692     Document Type: Article

References (65)

1. Anderson KM, Eckhart AD, Willette RN, Koch WJ. 1999. The myocardial beta- adrenergic system in spontaneously hypertensive heart failure (SHHF) rats. Hypertension 33:402-407.
2. Badenhorst D, Veliotes D, Maseko M, Tsotetsi O, Brooksbank R, Naidoo A, Woodiwiss A, Norton G. 2003. β-Adrenergic activation initiates chamber dilatation in concentric hypertrophy. Hypertension 41:499-504.
3. Barold S. 2001. 2:1 atrioventricular block: Order from chaos. Am. J. Emerg. Med 19:214-217.
4. Brook R, Brook J, Rajagopalan S. 2003. Air pollution: The "heart" of the problem. Curr. Hypertens. Rep 5:32-39.
5. Cambridge D, Whiting M. 1986. Evaluation of the QA interval as an index of cardiac contractility in anaesthetized dogs: responses to changes in cardiac loading and heart rate. Cardiovasc. Res 20: 444-450.
6. Campen MJ, Nolan JP, Schladweiler MCJ, Kodavanti UP, Evansky PA, Costa DL, et al. 2001. Cardiovascular and thermoregulatory effects of inhaled PM-associated transition metals: a potential interaction between nickel and vanadium sulfate. Toxicol. Sci 64:243-252.
7. Carll A, Haykal-Coates N, Winsett D, Hazari M, Ledbetter A, Callaway J, Richards J, Costa D, Farraj A. 2009. Acute exposure to particulate matter PM alters physiologic and toxicologic endpoints in a rat model of heart failure. Am. J. Respir. Crit. Care Med 179:A3145.
8. Cavallari J, Fang S, Eisen E, Schwartz J, Hauser R, Herrick R, Christiani D. 2008. Time course of heart rate variability decline following particulate matter exposures in an occupational cohort. Inhal. Toxicol 20:415-422
9. Chen C, Chow D, Chiamvimonvat N, Glatter K, Li N, He Y, Pinkerton K, Bonham A. 2008. Short-term secondhand smoke exposure decreases heart rate variability and increases arrhythmia susceptibility in mice. Am. J. Physiol. Heart Circ. Physiol 295:H632-H639.
10. Chung EK. 1983. Atrioventricular conduction disturbances. In: Principles of Cardiac Arrhythmias. 3rd ed. Baltimore: Williams & Wilkins, 267-338.
11. Cooklin M, Wallis W, Sheridan D, Fry C. 1997. Changes in cell-to-cell electrical coupling associated with left ventricular hypertrophy. Circ Res 80:765-771.
12. Costa D, Lehmann J, Winsett D, Richards J, Ledbetter A, Dreher K. 2006. Comparative pulmonary toxicological assessment of oil combustion particles following inhalation or instillation exposure. Toxicol. Sci 911:237-246.
13. Diwan A, Dorn G. 2006 Decompensation of cardiac hypertrophy: Cellular mechanisms and novel therapeutic targets. Physiology 22:56-64.
14. Dominici F, Peng R, Bell M, Pham L, McDermott A, Zeger S, Samet J. 2006. Fine particulate air pollution and hospital admission for cardiovascular and respiratory diseases. JAMA 295:1127-1134.
15. Dreher K, Jaskot R, Lehmann J, Richards J, McGee J, Ghio A, Costa D. 1997. Soluble transition metals mediate residual oil fly ash induced acute lung injury. J. Toxicol Environ Health 50:285-305.
16. 2-adrenergic- receptor subtypes on heart rate variability. Am. J. of Physiol. Heart Circ. Physiol 290:H192-H199.
17. Farraj A, Haykal-Coates N, Winsett D, Hazari M, Carll A, Rowan W, Ledbetter, A, Cascio W, Costa D. 2009. Increased non-conducted P-wave arrhythmias after a single oil fly ash inhalation exposure in hypertensive rats. Environ. Health Perspect 117(5):709-715.
18. Gardner S, McGee J, Kodavanti U, Ledbetter A, Everitt J, Winsett D, Doerfler D, Costa D. 2004. Emission-particle-induced ventilatory abnormalities in a rat model of pulmonary hypertension. Environ. Health Perspect 112(8):872-878.
19. Germano G, Angotti S, Muscolo M, D'Auria F, Giordano M. 1998. The dP/ dtmax derived from arterial pulse waveforms during 24 h blood pressure oscillometric recording. Blood Press. Monit 3:213-216.
20. Gilmour P, Schladweiler M, Richards J, Ledbetter A, Kodavanti U. 2004 Hypertensive rats are susceptible to TLR4-mediated signaling following exposure to combustion source particulate matter. Inhal. Toxicol 16(Suppl 1):5-18.
21. Goldberg M, Bailar J, Burnett R, Brook J, Tamblyn R, Bonvalot Y, Ernst P, Flegel K, Singh R, Valois M. 2000. Identifying subgroups of the general population that may be susceptible to short-term increases in particulate air pollution: A time-series study in Montreal, Quebec. Research Report, Health Effects Institute 97:7-120.
22. Hauser R, Elreedy S, Hoppin J, Christiani D. 1995. Airway obstruction in boilermakers exposed to fuel oil ash. A prospective investigation. Am. J. Respir. Crit. Care Med 152(5 Pt 1):1478-1484.
23. Heyen J, Blasi E, Nikula K, Rocha R, Daust H, Frierdich G, Van Vleet J, De Ciechi P, McMahon E, Rudolph A. 2002. Structural, functional, molecular characterization of the SHHF model of heart failure. Am J Physiol Heart Circ Physiol 283:H1775-H1784.
24. Jokinen M, Lieuallen W, Johnson C, Dunnick J, Nyska A. 2005. Characterization of spontaneous and chemically induced cardiac lesions in rodent model systems: The national toxicology program experience. Cardiovasc. Toxicol 5:227-244.
25. Kodavanti U, Hauser R, Christiani D, Meng Z, McGee J, Ledbetter A, Richards J, Costa D. 1998. Pulmonary responses to oil fly ash particles in the rat differ by virtue of their specific soluble metals. Toxicol. Sci 43:204-212.
26. Kodavanti U, Schladweiler M, Ledbetter A, Watkinson W, Campen M, Winsett D, Richards J, Crissman K, Hatch G, Costa D. 2000. The Spontaneously Hypertensive Rat as a model of human cardiovascular disease: Evidence of exacerbated cardiopulmonary injury and oxidative stress from inhaled emission particulate matter. Toxicol. and Appl. Pharmacol 164:250-263.
27. Ledbetter A, Killough P, Hudson G. 1998. A low-sample-consumption dryparticulate aerosol generator for use in nose-only inhalation exposures. Inhal. Toxicol 10:239-251.
28. Massin M, Derkenne B, von Bernuth G. 1999. Correlations between indices of heart rate variability in healthy children and children with congenital heart disease. Cardiology 91:109-113.
29. Milei J, Bolomo N. 1983. A routine method for diagnosis of early myocardial infarction. Int. J. of Cardiol 4:319-321.
30. Murray D, Prabhu S, Chandrasekar B. 2000. Chronic β-adrenergic stimulation induces myocardial proinflammatory cytokine expression. Circulation 101:2338-2341.
31. Nadziejko C, Chen L, Nadas A, Hwang J. 2004. The 'Fishing License' method for analysing the time course of effects in repeated measurements. Stat. Med 23:1399-1411.
32. Nerme V, Abrahamsson T, Vauquelin G. 1990. Chronic isoproterenol administration causes altered beta adrenoreceptor-Gs-coupling in guinea pig lung. J. Pharmacol Exp. Ther 252:1341-1346.
33. 2- adrenoreceptor messenger RNA with prolonged in vivo infusion of isoprenaline. Eur. J. Pharmacol. Mol. Pharmacol 247:131-138.
34. Notarius C, Floras J. 2001. Limitations of the use of spectral analysis of heart rate variability for the estimation of cardiac sympathetic activity in heart failure. Europace 3:29-38.
35. O'Grady M, O'Sullivan M. 2008. Clinical cardiology concepts for the dog and cat: Electrocardiology. VetGo Available at http://www.vetgo.com/cardio. Accessed 6 November 2008.
36. Ostro B, Feng W-Y, Broadwin R, Green S, Lipsett M. 2007. The effects of components of fine particulate air pollution on mortality in California: Results from CALFINE. Environ Health Perspect 114:13-19.
37. Pope C, Verrier R, Lovett E, Larson A, Raizenne M, Kanner R, Schwartz J, Villegas G, Gold D, Dockery D. 1999. Heart rate variability associated with particulate air pollution. Am. Heart J 138 5 Pt 1:890-899.
38. Pope C, Renlund D, Kfoury A, May H, Horne B. 2008. Relation of heart failure hospitalization to exposure to fine particulate air pollution. Am. J. Cardiol 102:1230-1234.
39. Rader D. 2007. Illuminating HDL-Is it still a viable therapeutic target N Engl J Med 2007, 35721:2180-2183.
40. Radin M, Holycross B, Hoepf T, McCune S. 2003. Increased salt sensitivity secondary to leptin resistance in SHHF rats is mediated by endothelin. Mol. Cell. Biochem 242:57-63.
41. Rhoden C, Wellenius G, Ghelfi E, Lawrence J, Gonzalez-Flecha B. 2005. PM-induced cardiac oxidative stress and dysfunction are mediated by autonomic stimulation. Biochim. Biophys. Acta 1725:305-313.
42. Riediker M, Devlin R, Griggs T, Herbst M, Bromberg P, Williams R, Cascio W. 2002. Cardiovascular effects in patrol officers is associated with fine particulate matter from break wear and engine emissions. Part. Fibre Toxicol 12:1-10.
43. Rivero D, Soares S, Lorenzi-Filho G, Saiki M, Godleski J, Antonangelo L, Dolhnikoff M, Saldiva P. 2005. Acute cardiopulmonary alterations induced by fine particulate matter of Sao Paulo, Brazil. Toxicol. Sci 85: 898-905.
44. Rona G. 1985. Catecholamine cardiotoxicity. J. Mol. Cell. Cardiol 17:291-306.
45. Rockman HA, Koch WJ, Lefkowitz RJ. 2002. Seven-transmembrane-spanning receptors and heart function. Nature 415:206-212.
46. Routledge H, Manney S, Harrison R, Ayres J, Townsend J. 2006. Effect of inhaled sulphur dioxide and carbon particles on heart rate variability and markers of inflammation and coagulation in human subjects. Heart 92:220-227.
47. Rowan W, Campen M, Wichers L, Watkinson W. 2007. Heart rate variability in rodents: Uses and caveats in toxicological studies. Cardiovasc. Toxicol 7:28-51.
48. Sanchez V, Hernandez-Munoz R, Lopez-Barrera F, Yanez L, Vidrio S, Suarez J, Cota-Garza D, Aranda-Fraustro A, Cruz D. 1997. Sequential changes of energy metabolism and mitochondrial function in myocardial infarction induced by isoproterenol in rats: A long-term and integrative study. Can. J. Physiol. Pharmacol 75:1300-1311
49. Schulz H, Harder V, Ibald-Mulli A, Khandoga A, Koenig W, Krombach F, Radykewicz R, Stampfl A, Thorand B, Peters A. 2005. Cardiovascular effects of fine and ultrafine particles. J. Aerosol Med 18:1-22.
50. 2-Adrenergic receptor genotype and pulmonary function in patients with heart failure. Chest 130: 1527-1534.
51. Stone P, Godleski J. 1999. First steps toward understanding the pathophysiologic link between air pollution and cardiac mortality. Am. Heart J 138(5 Pt 1):804-807.
52. Takeshita, D, Shimizu, J, Kitagawa, Y, Yamashita, D, Tohne, K, Nakajima-Takenaka, C, Ito, H, Takaki, M. 2008. Isoproterenol-induced hypertrophied rat hearts: Does short-term treatment correspond to long-term treatment? J Physiol. Sci 58:179-188
53. Tamura T, Said S, Gerdes AM. 1999. Gender-related differences in myocyte remodeling in progression to heart failure. Hypertension 33:676-680.
54. Tankersley C, Campen M, Bierman A, Flanders S, Broman K, Rabold R. 2004. Particle effects on heart-rate regulation in senescent mice. Inhal. Toxicol 2004, 16:381-390.
55. Tartiere J, Tabet J, Logeart D, Tartiere-Kesri L, Beauvais F, Chavelas C, Cohen Solal A. 2008. Noninvasively determined radial dP/dt is a predictor of mortality in patients with heart failure. Am. Heart J 155: 758-763
56. Taubes G. 2008. What's cholesterol got to do with it? New York Times, January 27. Opinions. Available at http://www.nytimes.com/2008/01/27/ opinion/27taubes.html. Accessed 13 November 2008.
57. Tomao E, Tiziana P, Rosati V, Marcellini L, Tomei F. 2002. The effects of air pollution on the lipid balance of traffic police personnel. Ann Saudi Med 22:297-1290
58. Towbin JA, Bowles NE. 2002. The failing heart. Nature 415:227-233.
59. Van Hee V, Adar S, Szpiro A. Barr R, Bluemke D, Roux A, Gill E, Sheppard L, Kaufman J. 2009. Exposure to traffic and left ventricular mass and function. Am. J. Respir. Crit. Care Med 179:827-834.
60. Watkinson W, Campen M, Costa D. 1998. Cardiac arrhythmia induction after exposure to residual oil fly ash particles in a rodent model of pulmonary hypertension. Toxicol. Sci 41:209-216.
61. Wichers L, Nolan J, Winsett D, Ledbetter A, Kodavanti U, Schladweiler M, Costa D, Watkinson W. 2004a. Effects of instilled combustion-derived particles in spontaneously hypertensive rats. Part I: Cardiovascular responses. Inhal. Toxicol 16:391-405.
62. Wichers L, Nolan J, Winsett D, Ledbetter A, Kodavanti U, Schladweiler M, Costa D, Watkinson W. 2004b. Effects of instilled combustion-derived particles in spontaneously hypertensive rats. Part II: Pulmonary responses. Inhal. Toxicol 16:407-419.
63. Yeatts K, Svendsen E, Creason J, Alexis N, Herbst M, Scott J, Kupper L, Williams R, Nease L, Cascio W, Devlin R, Peden D. 2007. Coarse particulate matter PM2.5-10 affects heart rate variability, blood lipids, and circulating eosinophils in adults with asthma. Environ. Health Perspect 115:709-714.
64. Zanobetti A, Schwartz J. 2007. Particulate air pollution, progression, and survival after myocardial infarction. Environ. Health Perspect 1155: 769-777.
65. 3-adrenergic stimulation in failing rat heart. J. Pharmacol. Exp. Ther 13:1203-1211.