Bisbenzamidine derivative, pentamidine represses DNA damage response through inhibition of histone H2A acetylation

Molecular Cancer

Volumn 9, Issue , 2010, Pages

  Kobayashi, Junya ^a   Kato, Akihiro ^a   Ota, Yosuke ^a   Ohba, Reiko ^a,b   Komatsu, Kenshi ^a  

^a KYOTO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF GENETICS   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ATM PROTEIN; BENZAMIDINE DERIVATIVE; DNA; EXONUCLEASE; HISTONE ACETYLTRANSFERASE; HISTONE H2A; HISTONE H2AX; MRE11 PROTEIN; NIBRIN; PENTAMIDINE; SMALL INTERFERING RNA; ATR PROTEIN, HUMAN; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; DNA DEPENDENT PROTEIN KINASE; ENZYME INHIBITOR; GREEN FLUORESCENT PROTEIN; HISTONE; HTATIP PROTEIN, HUMAN; MRE11A PROTEIN, HUMAN; NUCLEAR PROTEIN; PRKDC PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; TUMOR SUPPRESSOR PROTEIN;

ACETYLATION; ARTICLE; CELL LINE; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; DRUG MECHANISM; ENZYME ACTIVITY; FIBROBLAST; HELA CELL; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; INHIBITION KINETICS; RADIOSENSITIVITY; WESTERN BLOTTING; DNA REPAIR; DOUBLE STRANDED DNA BREAK; DRUG ANTAGONISM; DRUG EFFECT; GAMMA RADIATION; GENE SILENCING; GENETIC RECOMBINATION; GENETICS; IONIZING RADIATION; METABOLISM; RADIATION EXPOSURE; TUMOR CELL LINE;

ACETYLATION; BENZAMIDINES; CELL CYCLE PROTEINS; CELL LINE, TUMOR; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; DNA REPAIR; DNA-ACTIVATED PROTEIN KINASE; DNA-BINDING PROTEINS; ENZYME INHIBITORS; GAMMA RAYS; GENE KNOCKDOWN TECHNIQUES; GREEN FLUORESCENT PROTEINS; HISTONE ACETYLTRANSFERASES; HISTONES; HUMANS; NUCLEAR PROTEINS; PENTAMIDINE; PROTEIN-SERINE-THREONINE KINASES; RADIATION, IONIZING; RECOMBINATION, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 77949534654     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-9-34     Document Type: Article

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