Ionic flow enhances low-affinity binding: a revised mechanistic view into Mg2+ block of NMDA receptors

Journal of Physiology

Volumn 588, Issue 4, 2010, Pages 633-650

  Yang, Ya Chin ^a   Lee, Chia Hsueh ^b   Kuo, Chung Chin ^c  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

MAGNESIUM ION; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; CALCIUM ION; SODIUM ION;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BINDING KINETICS; BINDING SITE; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; DEPOLARIZATION; DISSOCIATION CONSTANT; ELECTRIC FIELD; FEMALE; HIPPOCAMPUS; ION CURRENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; ANIMAL TISSUE; APPARENT DISSOCIATION CONSTANT; BRAIN NERVE CELL; CALCIUM TRANSPORT; CHANNEL GATING; EXTRACELLULAR SPACE; INTRACELLULAR SPACE; LIGAND BINDING; MEMBRANE PERMEABILITY; NERVE CELL MEMBRANE STEADY POTENTIAL; RECEPTOR BLOCKING; SODIUM TRANSPORT;

ANIMALS; BINDING SITES; CA1 REGION, HIPPOCAMPAL; ION CHANNEL GATING; MAGNESIUM; NEURONS; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; VOLTAGE-DEPENDENT ANION CHANNELS;

EID: 77949525645     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2009.178913     Document Type: Article

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