Androgen receptor mutations associated with androgen insensitivity syndrome: A high content analysis approach leading to personalized medicine

PLoS ONE

Volumn 4, Issue 12, 2009, Pages

  Szafran, Adam T ^a   Hartig, Sean ^a   Sun, Huiying ^a   Uray, Ivan P ^a   Szwarc, Maria ^a   Shen, Yuqing ^a   Mediwala, Sanjay N ^a   Bell, Jennifer ^a   Mcphaul, Michael J ^b   Mancini, Michael A ^a   Marcelli, Marco ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; GREEN FLUORESCENT PROTEIN; AR PROTEIN, HUMAN; MUTANT PROTEIN;

ANALYTIC METHOD; ANDROGEN INSENSITIVITY SYNDROME; ARTICLE; CHO CELL; CONTROLLED STUDY; GENE MUTATION; GENETIC ASSOCIATION; GENETIC TRANSFECTION; GENITAL SYSTEM; HELA CELL; HIGH CONTENT ANALYSIS; HUMAN; HUMAN CELL; MICROSCOPY; MUTATIONAL ANALYSIS; PATHOGENESIS; PROTEIN ANALYSIS; PROTEIN FUNCTION; SKIN FIBROBLAST; AMINO ACID SUBSTITUTION; CELL NUCLEUS; CHEMISTRY; DOSE RESPONSE; DRUG POTENTIATION; FIBROBLAST; GENETIC TRANSCRIPTION; GENETICS; HIGH THROUGHPUT SCREENING; MALE; METABOLISM; METHODOLOGY; MUTATION; PERSONALIZED MEDICINE; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT;

AMINO ACID SUBSTITUTION; ANDROGEN-INSENSITIVITY SYNDROME; CELL NUCLEUS; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; HELA CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INDIVIDUALIZED MEDICINE; MALE; MUTANT PROTEINS; MUTATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECEPTORS, ANDROGEN; TRANSCRIPTION, GENETIC;

EID: 77949520128     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008179     Document Type: Article

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