Inhibition of HIV-1 replication in human monocyte-derived macrophages by parasite Trypanosoma cruzi

PLoS ONE

Volumn 4, Issue 12, 2009, Pages

  Andreani, Guadalupe ^a   Celentano, Ana M ^a   Solana, María E ^a   Cazorla, Silvia I ^a   Malchiodi, Emilio L ^a   Martínez Peralta, Liliana A ^a   Dolcini, Guillermina L ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; CRUZIPAIN; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; LUCIFERASE;

ANTIGEN PRESENTATION; ARTICLE; CELL SURFACE; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MACROPHAGE; MONOCYTE; NONHUMAN; ORGANISMAL INTERACTION; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; PSEUDOTYPING; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; TRYPANOSOMA CRUZI; TRYPOMASTIGOTE; VIRUS CELL INTERACTION; VIRUS DNA CELL DNA INTERACTION; VIRUS INHIBITION; VIRUS REPLICATION; WILD TYPE;

ANIMALS; ANTIGENS, CD4; ANTIGENS, PROTOZOAN; CYSTEINE ENDOPEPTIDASES; HIV-1; HUMANS; MACROPHAGES; MICE; MONOCYTES; ORGAN SPECIFICITY; PARASITES; RECEPTORS, CCR5; SOLUBILITY; TRYPANOSOMA CRUZI; VIRUS ASSEMBLY; VIRUS INTEGRATION; VIRUS INTERNALIZATION; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1; PROTOZOA; TRYPANOSOMA CRUZI; VESICULAR STOMATITIS VIRUS;

EID: 77949515734     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008246     Document Type: Article

References (63)

1. Stevenson M, Gendelman HE (1994) Cellular and viral determinants that regulate HIV-1 infection in macrophages. J Leukoc Biol 56: 278-288.
2. Karp CL, Auwaerter PG (2007) Coinfection with HIV and tropical infectious diseases. II. Helminthic, fungal, bacterial, and viral pathogens. Clin Infect Dis 45: 1214-1220.
3. Karp CL, Auwaerter PG (2007) Coinfection with HIV and tropical infectious diseases. I. Protozoal pathogens. Clin Infect Dis 45: 1208-1213.
4. Aquaro S, Balestra E, Cenci A, Francesconi M, Calio R, et al. (1997) HIV infection in macrophage: role of long-lived cells and related therapeutical strategies. J Biol Regul Homeost Agents 11: 69-73.
5. Gendelman HE, Orenstein JM, Baca LM, Weiser B, Burger H, et al. (1989) The macrophage in the persistence and pathogenesis of HIV infection. Aids 3: 475-495.
6. Meltzer MS, Skillman DR, Gomatos PJ, Kalter DC, Gendelman HE (1990) Role of mononuclear phagocytes in the pathogenesis of human immunod eficiency virus infection. Annu Rev Immunol 8: 169-194.
7. Goletti D, Carrara S, Vincenti D, Giacomini E, Fattorini L, et al. (2004) Inhibition of HIV-1 replication in monocyte-derived macrophages by Mycobacterium tuberculosis. J Infect Dis 189: 624-633.
8. Zhao C, Papadopoulou B, Tremblay MJ (2004) Leishmania infantum enhances human immunodeficiency virus type-1 replication in primary human macrophages through a complex cytokine network. Clin Immunol 113: 81-88.
9. Zhao C, Papadopoulou B, Tremblay MJ (2004) Leishmania infantum promotes replication of HIV type 1 in human lymphoid tissue cultured ex vivo by inducing secretion of the proinflammatory cytokines TNF-alpha and IL-1 alpha. J Immunol 172: 3086-3093.
10. Barrett MP, Burchmore RJ, Stich A, Lazzari JO, Frasch AC, et al. (2003) The trypanosomiases. Lancet 362: 1469-1480.
11. Morel CM, Lazdins J (2003) Chagas disease. Nat Rev Microbiol 1: 14-15.
12. PAHO (September 2003) American trypanosomiasis (Chagas' disease). Epidemiological Bulletin. Available at http://www.paho.org/english/dd/ais/be_v24n3-amer_trypa.htm.
13. Vaidian AK, Weiss LM, Tanowitz HB (2004) Chagas' disease and AIDS. Kinetoplastid Biol Dis 3: 2.
14. Guarner J, Bartlett J, Zaki SR, Colley DG, Grijalva MJ, et al. (2001) Mouse model for Chagas disease: immunohistochemical distribution of different stages of Trypanosoma cruzi in tissues throughout infection. Am J Trop Med Hyg 65: 152-158.
15. Marin-Neto JA, Cunha-Neto E, Maciel BC, Simoes MV (2007) Pathogenesis of chronic Chagas heart disease. Circulation 115: 1109-1123.
16. Ferreira MS, Borges AS (2002) Some aspects of protozoan infections in immunocompromised patientsa review. Mem Inst Oswaldo Cruz 97: 443-457.
17. Harms G, Feldmeier H (2002) HIV infection and tropical parasitic diseases - deleterious interactions in both directions? Trop Med Int Health 7: 479-488.
18. Sartori AM, Ibrahim KY, Nunes Westphalen EV, Braz LM, Oliveira OC, Jr., et al. (2007) Manifestations of Chagas disease (American trypanosomiasis) in patients with HIV/AIDS. Ann Trop Med Parasitol 101: 31-50.
19. Carruthers VB, Blackman MJ (2005) A new release on life: emerging concepts in proteolysis and parasite invasion. Mol Microbiol 55: 1617-1630.
20. Denkers EY, Butcher BA (2005) Sabotage and exploitation in macrophages parasitized by intracellular protozoans. Trends Parasitol 21: 35-41.
21. Luder CG, Gross U, Lopes MF (2001) Intracellular protozoan parasites and apoptosis: diverse strategies to modulate parasite-host interactions. Trends Parasitol 17: 480-486.
22. Sibley LD (2004) Intracellular parasite invasion strategies. Science 304: 248-253.
23. Gruppi A, Cerban FM, Vottero-Cima E (1997) Exoantigens from Trypanosoma cruzi contain cruzipain. Acta Trop 63: 141-149.
24. Frank FM, Petray PB, Cazorla SI, Munoz MC, Corral RS, et al. (2003) Use of a purified Trypanosoma cruzi antigen and CpG oligodeoxynucleotides for immuno-protection against a lethal challenge with trypomastigotes. Vaccine 22: 77-86.
25. Burleigh BA, Woolsey AM (2002) Cell signalling and Trypanosoma cruzi invasion. Cell Microbiol 4: 701-711.
26. Dolcini GL, Solana ME, Andreani G, Celentano AM, Parodi LM, et al. (2008) Trypanosoma cruzi (Chagas' disease agent) reduces HIV-1 replication in human placenta. Retrovirology 5: 53.
27. Celentano AM, Gonzalez Cappa SM (1992) Induction of macrophage activation and opsonizing antibodies by Trypanosoma cruzi subpopulations. Parasite Immunol 14: 155-167.
28. Risso MG, Garbarino GB, Mocetti E, Campetella O, Gonzalez Cappa SM, et al. (2004) Differential expression of a virulence factor, the trans-sialidase, by the main Trypanosoma cruzi phylogenetic lineages. J Infect Dis 189: 2250-2259.
29. David A, Saez-Cirion A, Versmisse P, Malbec O, Iannascoli B, et al. (2006) The engagement of activating FcgammaRs inhibits primate lentivirus replication in human macrophages. J Immunol 177: 6291-6300.
30. Scharfstein J, Schechter M, Senna M, Peralta JM, Mendonca-Previato L, et al. (1986) Trypanosoma cruzi: characterization and isolation of a 57/51,000 m.w. surface glycoprotein (GP57/51) expressed by epimastigotes and bloodstream trypomastigotes. J Immunol 137: 1336-1341.
31. Sajid M, McKerrow JH (2002) Cysteine proteases of parasitic organisms. Mol Biochem Parasitol 120: 1-21.
32. Sartori AM, Caiaffa-Filho HH, Bezerra RC, do SGC, Lopes MH, et al. (2002) Exacerbation of HIV viral load simultaneous with asymptomatic reactivation of chronic Chagas' disease. Am J Trop Med Hyg 67: 521-523.
33. Tarleton RL (2007) Immune system recognition of Trypanosoma cruzi. Curr Opin Immunol 19: 430-434.
34. Koenig S, Gendelman HE, Orenstein JM, Dal Canto MC, Pezeshkpour GH, et al. (1986) Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science 233: 1089-1093.
35. Akkina RK, Walton RM, Chen ML, Li QX, Planelles V, et al. (1996) High-efficiency gene transfer into CD34+ cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G. J Virol 70: 2581-2585.
36. Lin YL, Mettling C, Portales P, Reynes J, Clot J, et al. (2002) Cell surface CCR5 density determines the postentry efficiency of R5 HIV-1 infection. Proc Natl Acad Sci U S A 99: 15590-15595.
37. Marechal V, Prevost MC, Petit C, Perret E, Heard JM, et al. (2001) Human immunodeficiency virus type 1 entry into macrophages mediated by macropinocytosis. J Virol 75: 11166-11177.
38. Miller MD, Farnet CM, Bushman FD (1997) Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition. J Virol 71: 5382-5390.
39. Gurer C, Hoglund A, Hoglund S, Luban J (2005) ATP gamma S disrupts human immunodeficiency virus type 1 virion core integrity. J Virol 79: 5557-5567.
40. Rosestolato CT, Dutra Jda M, De Souza W, de Carvalho TM (2002) Participation of host cell actin filaments during interaction of trypomastigote forms of Trypanosoma cruzi with host cells. Cell Struct Funct 27: 91-98.
41. Woolsey AM, Burleigh BA (2004) Host cell actin polymerization is required for cellular retention of Trypanosoma cruzi and early association with endosomal/ lysosomal compartments. Cell Microbiol 6: 829-838.
42. Warrilow D, Harrich D (2007) HIV-1 replication from after cell entry to the nuclear periphery. Curr HIV Res 5: 293-299.
43. Grivel JC, Ito Y, Faga G, Santoro F, Shaheen F, et al. (2001) Suppression of CCR5-but not CXCR4-tropic HIV-1 in lymphoid tissue by human herpesvirus 6. Nat Med 7: 1232-1235.
44. Grivel JC, Garcia M, Moss WJ, Margolis LB (2005) Inhibition of HIV-1 replication in human lymphoid tissues ex vivo by measles virus. J Infect Dis 192: 71-78.
45. Xiang J, McLinden JH, Chang Q, Kaufman TM, Stapleton JT (2006) An 85-aa segment of the GB virus type C NS5A phosphoprotein inhibits HIV-1 replication in CD4+ Jurkat T cells. Proc Natl Acad Sci U S A 103: 15570-15575.
46. Garcia M, Yu XF, Griffin DE, Moss WJ (2008) Measles virus inhibits human immunodeficiency virus type 1 reverse transcription and replication by blocking cell-cycle progression of CD4+ T lymphocytes. J Gen Virol 89: 984-993.
47. Xiang J, McLinden JH, Chang Q, Jordan EL, Stapleton JT (2008) Characterization of a peptide domain within the GB virus C NS5A phosphoprotein that inhibits HIV replication. PLoS ONE 3: e2580.
48. Golding H, Khurana S, Yarovinsky F, King LR, Abdoulaeva G, et al. (2005) CCR5 N-terminal region plays a critical role in HIV-1 inhibition by Toxoplasma gondii-derived cyclophilin-18. J Biol Chem 280: 29570-29577.
49. Alfano M, Rizzi C, Corti D, Adduce L, Poli G (2005) Bacterial toxins: potential weapons against HIV infection. Curr Pharm Des 11: 2909-2926.
50. Brodskyn C, Patricio J, Oliveira R, Lobo L, Arnholdt A, et al. (2002) Glycoinositolphospholipids from Trypanosoma cruzi interfere with macrophages and dendritic cell responses. Infect Immun 70: 3736-3743.
51. de Diego J, Punzon C, Duarte M, Fresno M (1997) Alteration of macrophage function by a Trypanosoma cruzi membrane mucin. J Immunol 159: 4983-4989.
52. Rubin-de-Celis SS, Uemura H, Yoshida N, Schenkman S (2006) Expression of trypomastigote trans-sialidase in metacyclic forms of Trypanosoma cruzi increases parasite escape from its parasitophorous vacuole. Cell Microbiol 8: 1888-1898.
53. Souto-Padron T, Campetella OE, Cazzulo JJ, de Souza W (1990) Cysteine proteinase in Trypanosoma cruzi: immunocytochemical localization and involvement in parasite-host cell interaction. J Cell Sci 96(Pt 3): 485-490.
54. Cazorla SI, Becker PD, Frank FM, Ebensen T, Sartori MJ, et al. (2008) Oral vaccination with Salmonella enterica as a cruzipain-DNA delivery system confers protective immunity against Trypanosoma cruzi. Infect Immun 76: 324-333.
55. Cazorla SI, Frank FM, Becker PD, Corral RS, Guzman CA, et al. (2008) Prime-boost immunization with cruzipain co-administered with MALP-2 triggers a protective immune response able to decrease parasite burden and tissue injury in an experimental Trypanosoma cruzi infection model. Vaccine 26: 1999-2009.
56. Kedzierska K, Crowe SM, Turville S, Cunningham AL (2003) The influence of cytokines, chemokines and their receptors on HIV-1 replication in monocytes and macrophages. Rev Med Virol 13: 39-56.
57. Perez-Ramirez L, Barnabe C, Sartori AM, Ferreira MS, Tolezano JE, et al. (1999) Clinical analysis and parasite genetic diversity in human immunodeficiency virus/Chagas' disease coinfections in Brazil. Am J Trop Med Hyg 61: 198-206.
58. Sartori AM, Lopes MH, Caramelli B, Duarte MI, Pinto PL, et al. (1995) Simultaneous occurrence of acute myocarditis and reactivated Chagas' disease in a patient with AIDS. Clin Infect Dis 21: 1297-1299.
59. Sartori AM, Shikanai-Yasuda MA, Amato Neto V, Lopes MH (1998) Follow-up of 18 patients with human immunodeficiency virus infection and chronic Chagas' disease, with reactivation of Chagas' disease causing cardiac disease in three patients. Clin Infect Dis 26: 177-179.
60. Sorice M, Garofalo T, Misasi R, Longo A, Mattei V, et al. (2001) Evidence for cell surface association between CXCR4 and ganglioside GM3 after gp120 binding in SupT1 lymphoblastoid cells. FEBS Lett 506: 55-60.
61. Dolcini G, Derrien M, Chaouat G, Barre-Sinoussi F, Menu E (2003) Cell-free HIV type 1 infection is restricted in the human trophoblast choriocarcinoma BeWo cell line, even with expression of CD4, CXCR4 and CCR5. AIDS Res Hum Retroviruses 19: 857-864.
62. Connor RI, Chen BK, Choe S, Landau NR (1995) Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes. Virology 206: 935-944.
63. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.