Some aspects of protozoan infections in immunocompromised patients - A review

Memorias do Instituto Oswaldo Cruz

Volumn 97, Issue 4, 2002, Pages 443-457

  Ferreira, Marcelo Simão ^a   Borges, Aércio Sebastião ^a  

^a FEDERAL UNIVERSITY OF UBERLÂNDIA   (Brazil)

Author keywords

Acquired immunodeficiency syndrome Aids; Opportunistic infections; Protozoa

Indexed keywords

AIDS RELATED COMPLEX; ANIMAL; CHAGAS DISEASE; CRYPTOSPORIDIOSIS; HUMAN; IMMUNE DEFICIENCY; IMMUNOLOGY; LEISHMANIASIS; PARASITOLOGY; PROTOZOAL INFECTION; REVIEW; TOXOPLASMOSIS;

AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANIMALS; CHAGAS DISEASE; CRYPTOSPORIDIOSIS; HUMANS; IMMUNOCOMPROMISED HOST; LEISHMANIASIS; PROTOZOAN INFECTIONS; TOXOPLASMOSIS;

EID: 0036599005     PISSN: 00740276     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0074-02762002000400001     Document Type: Article

References (161)

1. Actor JK, Shiarai M, Kullberg MC, Buller RM, Sher A, Berzojsky JA 1993. Helminth infection results in decreased virus-specific CD8 + cytotoxic T cell and ThI cytokine responses as well as delayed virus clearence. Proc Natl Acad Sci USA 90: 948-952
2. Albrecht H 1998. Leishmaniasis: new perspectives on an underappreciated opportunistic infection. AIDS 12: 2225-2226
3. Almeida, EA Engelman, DES, Metze, K Teixeira, MAB, Tostes JR, Lopes ER 1974. Encefalopatia chagásica em immunodeprimido por tratamento quimioterápico em portador de leucose crônica: apresentação de caso com necrópsia. Rev Soc Bras Med Trop 24 (Supl. I): 33.
4. Alvar J 1994. Leishmaniasis and AIDS co-infection, the Spanish example. Parasitol Today 10: 160-163.
5. Alvar J, Canavate C, Gutierrez-Solar B, Jimenez M, Laguna F, Lopez-Velez R, Molina R, Moreno J 1997. Leishmania and human immunonodeficiency virus confection: the first 10 years. Clin Microbiol Rev 10: 298-319.
6. Amato Neto V 1970. Aspectos dermatologicos da toxoplasmose. Rev Soc Bras Med Trop 5: 345-348.
7. Amato Neto V, Doles J, Rassi A, Borges AP, Rezende JM, Gomes COM 1968. Relato de novos casos de transmissão da doença de Chagas por transfusão de sangue. Rev Inst Med Trop São Paulo 10: 46-51.
8. Ambroise-Thomas P, Pelloux A 1993. Toxoplasmosis - congenital and in immunocompromised patients: a parallel. Parasitol Today 9: 61-63.
9. Amendoeira MRR 1995. Mecanismos de transmissào da toxoplasmose, Anais Acad Nac Med 155: 224-225.
10. Anonymous 1996. Pautas para la prevención de infecciones oportunistas en personas com VIH o Sida em America Latina Yel Caribe. Bol Oficina Sanit Panam 121: 377-403.
11. Araujo FG 1991 Depletion of L3T4(CD4) T lymphocytes prevents development of resistence to Toxoplasma gondii in mice. Inject Immun 45: 122-126.
12. Araujo FG, Remington JS 1980. Antigenemia in recently acquired acute toxoplasmosis. J Infect Dis 141: 144-150.
13. Bertoli F, Espino M, Arosemena JR, Fishback JL, Frenkel JK 1995. A spectrum in the pathology of toxoplasmosis in patients with acquired immunodeficiency syndrome. Arch Pathol Laborat Med 119: 214-224.
14. Bocchi EA, Bellotti G, Uip L, Kalil J, Higushi ML, Fiorelli A, Stolf N, Janete A, Pillegi F 1993. Long term follow-up after heart transplantation in Chagas disease. Transplantation 25: 1329-1330.
15. Bonacini M 1992. Hepatobiliary complications in patients with human immunodeficiency virus infection. Am J Med 92: 404-411.
16. Borges AS, Ferreira MS, Nishioka AS, Silvestre MTA. Silva AM, Rocha A 1997. Agreement between premortem and postmortem diagnoses in patients with acquired immunodeficiency syndrome observed at a Brazilian Teaching Hospital. Rev Inst Med Trop SP 39: 217-221.
17. Borges AS, Figueiredo JFC 2000a. Pesquisa de anticorpos de classe IgG, IgM e IgA, anti-T gondii, no soro, liquor e saliva de pacientes com sindrome da imunodeficiência adquirida e neurotoxoplasmose. Rev Soc Brasil Med Trop 33 (S-1): 353.
18. Borges AS, Figueiredo JFC 2000b. Determinação da produção de anticorpos anti-T. gondii a nivel de sistema nervoso central como subsidio para o diagnóstico da neurotoxoplasmose em pacientes com sindrome da imunodeficiência adquirida. Rev Soc Brasil Med Trop 33 (S-1): 354.
19. Borges AS, Machado, Ferreira MS, Figueiredo JFC, Silva GF, Cimerman S, Bacha H, Teixeira MCL 1999. Concomitância de leishmanioses e infecção pelos virus da imunodeficiência humana (HIV): estudo de quatro casos. Rev Soc Bras Med Trop 32: 713-719.
20. Brenner Z, Chiari E 1971. The effects of some immunosupressive agents in experimental chronic Chagas' disease. Trans R Soc Trop Med Hyg 65: 729-636.
21. Cantarovich F, Vazquez M, Duro Garcia W, Abbud Filho M, Herrera C, Villegas Hernandez A 1992. Special Infections in organ transplantation in South América. Transplantation 24: 1902-1908.
22. Cardell RL, Addiss DG 1994. Cryptosporidiosis in child care settings: a review of the literature and recomendations for prevention and control. Pediat Infect Dis J 13: 310-317.
23. Carey RM, Kimball AC, Armstrong D, Lieberman PH 1973. Toxoplasmosis. Clinical experiences in a cancer hospital. Am J Med 54: 30-38.
24. Cello JP, Grendell JH, Basuk P 1991. Effect of octreotide on refractory AIDS associated diarrhea - a prospective multicenter clinical trial. Ann Intern Med 115: 705-710.
25. Cesbron-Delauw MF 1994. Dense-granule organelles of Toxoplasma gondii: their role in the host-parasite relationship. Parasitol Today 10: 296.
26. Chocair PR, Sabbaga E, Amato Neto V, Shiroma M, Goes GM 1981. Transplante de rim: nova modalidade de transmissào da doença de Chagas. Rev Inst Med Trop São Paulo 18: 43-45.
27. Clezy K, Gold J, Blaze J, Jones P 1991. Paramomycin for the treatment of cryptosporidial diarrhea in AIDS patients. AIDS 5: 1146-1147.
28. Cohn JA, McMeeking A, Cohen W, Jacobs J, Holtzman RS 1989. Evaluation of the policy of empiric treatment of suspected toxoplasma encephalitis in patients with the acquired immunodeficiency syndrome. Am J Med 86: 521-527.
29. Conley FK, Jenkins KA 1981. Immunohistological study of the anatomic relationship of toxoplasma antigens to the inflamatory response in the brains of mice chronically infected with Toxoplasma gondii. Infect Immun 31: 1184-1192.
30. Corona S, Amanales C, Avaria MLA, Colin E, Donoso S, Advis P, Apt W 1988. Granuloma chagásico del cerebro en um paciente com leucemia linfoblástica. Rev Med Chile 116: 676-80.
31. Costa-Cruz JM, Ferreira MS 1996. Intestinal parasites in AIDS and + HIV patients in Uberlândia, Minas Gerais, Brazil. Mem Inst Oswalde Cruz 91: 685-686.
32. Coura JR, Galvão Castro B, Grimaldi G 1987. Disseminated american cutaneous leishmaniasis in a patient with AIDS. Mem Inst Oswaldo Cruz 82: 581-582.
33. Dannemann BR, Israelski DM, Leoung GS, McGraw T, Mills J, Remington JS 1991. Toxoplasma serology, parasitemia and antigenemia in patients at risk for toxoplasmic encephalitis. AIDS 5: 1363-1365.
34. Danneman BR, McCutchan JA, Israelski DM, Antoniskis D, Leport C, Luft B, Nussbaujm J, Clumeck N, Morlat P, Chiu J, Vildé JL, Orellana M, Feigal D, Bartok A, Heseltin P, Leedom J, Remington J 1992. Treatment of toxoplasmic encephalitis in patients with AIDS: a randomized trial comparing pyrimethamine plus clindamycin to pyrimethamine plus sulfonamides. Ann Int Med 116: 33-43.
35. Darcy F, Santoro F 1994. Toxoplasmosis. In F Kierszenbaum, Parasitic Infect Imm System, Academic Press, Inc., New York, P. 163-201.
36. Darcy F, Foudrinier F, Mougeot G, Decoster A, Caron A, MarxChemla C, Capron A, Pinon JM 1991. Diagnostic value of specific IgA antibodies in AIDS patients with Toxoplasma infection: a bicentric evaluation. Immunol Let 30: 345-348.
37. Davidson RN, Russo R 1994. Relapse of visceral leishmaniasis in patients who were coinfected with human immnodeficiency virus and who received treatment with liposomal amphotericin B. Clin Infect Dis 16: 397-395.
38. De Artega J, Massari PV, Galli B, Garzon Maceda F, Zlocowsky JC 1992. Renal transplantation and Chagas' disease. Transplantation 24: 1900-1901.
39. De Gorgolas M, Castrill JM. Fernandez Guereiro ML 1993. Visceral leishmaniasis in patients with AIDS: report of three cases treated with pentavalent antimony and interferon. Clin Infect Dis 17: 56-58.
40. Dedet JP, Lambert M, Pratlong F 1995. Leishmanioses et infection par le virus de immunodeficience humaine. Presse Medicale 24: 1036-1040.
41. Derouin F, Mazeron MC, Garin YJD 1997. Comparative study of tissue culture and mouse inoculation methods for demonstration of Toxoplasma gondii. J Clin Microbiol 25: 1597-1600.
42. Dupouy-Camet J, Souza SL, Maslo C, Paugam A, Saimot AG, Benarous R, Tourte-Schaefer C, Derouin F 1993. Detection of Toxoplasma gondii in venous blood from AIDS patients by polymerase chain reaction. J Clin Microb 31: 1866-1869.
43. Eisemberg JNS, Priest JW, Lammie PJ, Colford JM 2001. The serologic response to Cryptospiridium in HIV-infected persons: implications for epidemiologia research. Emerging Infect Dis 7: 1004-1009.
44. Fachado A, Fonte L, Alberti E, Hadad P, Fonseca L, Machin R, Finlay C 1994. Usefulness of the detection of Toxoplasma gondii antigens in AIDS patients. Rev Inst Med Trop São Paulo 36: 525-529.
45. Fauci AS 1984. Immunologic abnormalities in the acquired immunodeficiency syndrome. Clin Res 32: 491-499.
46. Faycr R Ungar BLP 1986. Cryptosporidium spp. and cryptospridiosis. Microbiol Rev 50: 458-483.
47. Feldman HA 1968. Toxoplasmosis. N Eng J Med 279: 1370-1375.
48. Felgenhauer K 1982. Differentiation of the humoral immune response in inflammatory disease of the central nervous system. J Neural 228: 223-237.
49. Fernandez Guerrero ML, Aguado JM, Buzin L, Barros C, Montalban C, Martin T, Souza E 1987. Visceral leishmaniasis in immnocompromised hosts. Am J Med 83: 1098-1102.
50. Ferreira MS 1999. Chagas disease and immunossupression. Mem Inst Oswaldo Cruz 94: 325-327.
51. Ferreira MS, Nishioka AS, Rocha A, Silva AM, Ferreira RG, Olivier W, Tostes Jr S 1991. Acute fatal Trypanosoma cruzi meningoencefalitis in a hemophiliac patient. Am J Trop Med Hyg 45: 723-727.
52. Ferreira MS, Nishioka SA, Silvestre MT, Borges AS, Nunes Araújo FR, Rocha A 1997. Reactivation of Chagas disease in patients with AIDS: review of the literature. Clin Infect Dis 25: 1397-1400.
53. Fichtenbanm CJ, Ritchie DJ, Powderly WG 1993. Use of paramomycin for treatment of cryptosporidiosis in patients with AIDS. Clin Infect Dis 16: 298-300.
54. Figueiredo, JFC, Martinez R, Costa JC, Moysés Neto M, Suaid HJ Ferraz AS 1990. Transmission of Chagas' disease through renal transplantation: report a case. Trans R Soc Trop Med Hyg 84: 61-62.
55. Figueiredo JFC, Neto MM, Gomes VA, Suaid H, Ferraz AS, Martins ACP, Fiorillo AM 1983. Antibody titers to Toxoplasma gondii in renal transplant patients. Braz J Med Biol Res 16: 235-239.
56. Flanigan T, Whalen C, Turner J 1992. Cryptosporidiosis infection and CD4 counts. Ann Intern Med 116: 840-842.
57. França LCM, Fleury R N, Ramos Jr HÁ, Lemos S, Melaragno Filho R, Pasternak J 1969. Moléstia de Chagas crônica associada à leucemia linfática: ocorrência de encefalite aguda como alteração do estado imunitário. Arg Neuropsiquiatr (São Paulo) 27: 59-66.
58. Frenkel JC, Nelson BM, Arias-Stella J 1975. Immunossupression and toxoplasmic encephalitis. Clinical and experimental aspects. Hum Pathol 6: 97-111.
59. Frenkel JK 1957. Effects of cortisone, total body irradiation and nitrogen mustard on chronic latent toxoplasmosis. Am J Pathol 33: 618.
60. Frenkel JK 1973. Toxoplasma in and around us. Bio Sci 23: 343-352.
61. Frenkel JK 1988. Pathophysiology of toxoplasmosis. Parasitol Today 4: 273-278.
62. Fuccillo EA, Madden EE, Tzan N, Sever JL 1987. Difficulties associated with serological diagnosis of Toxoplasma gondii infections. Diag Clin Imm 5: 8-13.
63. Garly M, Eskild P, Petersen C, Lundgren JD, Gerstoft J 1997. Toxoplasmosis in Danish AIDS patients. Scand J Infect Dis 29: 597-600.
64. Gazzinelli RT, Eltowm I, Wynn TA, Sher A 1993. Acute cerebral toxoplasmosis is induzed by "in vivo" neutralization of TNF-α and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation. J Immunol 151: 3672-3681.
65. Gazzinelli RT, Hakim FT, Hieny S, Shearer GM, Sher A 1991. Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-γ production and protective immunity induced by an attenuated Toxoplasma gondii vaccine. J Immunol 146: 286-292.
66. Gazzinelli RT, Wysocka M, Hayashi S, Denkers EY, Hieny S, Caspar P, Trinchieri G, Sher A 1994. Parasite-induced IL-12 stimulates early INF-γ synthesis and resistance during acute infection with Toxoplasma gondii. J Immunol 153: 2533-2542.
67. Gazzinelli RT, Xu Y, Hieny S, Cheever A, Sher A 1992. Simultaneous depletion of CD4+ and CD8+ T lymphocytes is required to reactivate chronic infection with Toxoplasma gondii. J Immunol 149: 175-180.
68. Geiseler PJ, Ito JL, Tegtmeir BR, Kerndt PR, Kranee R 1987. Fulminant Chagas disease in bone morrow transplantation (BMT). In Program and Abstracts of the 27 th Interscience Conference on Antimicrobial Agents and Chemotherapy, New York, Washington DC, p. 169.
69. Gilks CF 1993. The clinical challenge of the HIV epidemic in the developing world. Lancet 342: 1037-1039.
70. Gluckstein D, Ciferri F, Ruskin J 1992. Chagas' disease another cause of cerebral mass in the acquired immunodeficiency syndrome. Am J Med 92: 429-432.
71. Goldstein ST, Jurane KDD, Ravenholt O 1996. Cryptosporidiosis: an outbreak associated with drinking water despite state-of-art water treatment. Ann Intern Med 124: 459-468.
72. Gradoni L, Scalone A, Gramiccia M, Troiani M 1996. Epidemiological surveillance of leishmaniasis in HIV-1 infected individuals in Italy. AIDS 10: 785-791.
73. Grant IH, Gold JWM, Rosenblum M, Niedzwiecki D, Armstrong D 1990. Toxoplasma gondii serology in HIV-infected patients: the development of central nervous system toxoplasmosis in AIDS. AIDS 4: 519-521.
74. Grant IH, Gold JWM, Wittner M, Tamowitz HB, Nathan C, Mayer K, Reich L, Wollner N, Steinherz L, Ghavini F, O' Reilly RJ, Armstrong D 1989. Transfusion associted acute Chagas' disease acquired in the United States. Ann Int Med 111: 849-851.
75. Gray GF, Gherarde R, Wingate E, Wingate J, Fenelon G, Gaston A, Sobel A, Poiner J 1989. Diffuse encephalic cerebral toxoplasmosis in AIDS: report of 4 cases. J Neurol 236: 273-277.
76. Griffiths JK 1998. Human cryptosporidiosis: epidemiology, transmission, clinical disease, treatment and diagnosis. Adv Parasitol 40: 37-85.
77. Gross U, Roos T, Appoldt D, Heesemann J 1992. Improved serological diagnosis of Toxoplasma gondii infection by detection of immunoglobulin A (IgA) and IgM antibodies against P30 by using immunoblot technique. J Clin Microbiol 30: 1436-1441.
78. Guerrant RL 1997. Cryptosporidiosis: an emerging, highly infectios threat. Emerging Infect Dis 3: 51-55.
79. Hafid J, Tranmanh SR, Raberin H, Akono ZY, Pozzetto B, Jana M 1995. Detection of circulating antigens of Toxoplasma gondii in human infection. Am J Trop Med Hyg 52: 336-339.
80. Hakes TB, Armstrong D 1983. Toxoplasmosis. Problems in diagnosis and treatment. Cancer 52: 1535-1540.
81. Herwaldt BL, Juranok DD 1993. Laboratory acquired malaria, leishmaniasis, trypanosomiasis and toxoplasmosis. Am Soc Trop Hyg 48: 313-323.
82. Hewitt RG, Yiannoutsos CT, Higgs ES, Carey JT, Geiseler PJ, Soave R, Rosemberg R, Vazquez GJ, Wheat LJ, Fass RJ, Antoninevic Z, Walawander AL, Flanigan TP, Bender JH 2000. Paramomycin: no more effective than placebo for tratment of cryptosporidiosis in patients with advanced human immunodeficiency virus infection. Clin Infect Dis 31: 1084-1092.
83. Hofflin JM, Remington JS 1985. Tissue culture isolation of Toxoplasma from blood of a patient with AIDS. Arch Int Med 145: 925-926.
84. Hoxie NJ, Davis JP, Vergeront JM, Nashold R, Blair KA 1997. Cryptosporidiosis-associated mortality following a massive waterborne outbreak in Milwaukee, Wisconsin. Am J Publ Health 87: 2032-2035.
85. Huskinson J, Thulliez P, Remington JS 1990. Toxoplasma antigens recognized by human immunoglobulin A antibodies. J Clin Microb 28: 2632-2636.
86. Israelski DM, Remington JS 1993. Toxoplasmosis in the nonAIDS immunocompromised host. In J Remington, M Swartz (eds), Current Clinical Topics in Infectious Diseases, Vol. 13, Blacwell Scientific, London, p. 322-356.
87. Jautzke G, Sell M, Thai Mann V, Janitschke K, Gottscha LK, Schurmann D, Ruf B 1993. Extracerebral toxoplasmosis in AIDS: histological and immunohistological findings based on 80 autopsy cases. Pathol Res Pract 189: 428-436.
88. Johnson WD 1981. Chronological development of cellular immunity in human toxoplasmosis. Infect Immun 33: 948-949.
89. Jost L, Turin M, E Tchegoyen F, Leiguarda R, Torcuato A, Iotti R 1977. Meningoencefalite chagasica em paciente com tratamento inmunosupresor por transplante renal. Rev Neurol Arg 3: 425-428.
90. Karp CL, Neva FA 1999. Tropical infections diaseases in human imumunodeficient virus-infected pacients. Clin Infect Dis 28: 947-965.
91. Katlama C, De Witt S, O'Doherty E 1996. Pyrimethamine-clindamycin vs. Pyrimethamine-sulladiazine as acute and long-term therapy for toxoplamic encephalitis in patients with AIDS. Clin Infect Dis 22: 268.
92. Kaufmann SHE 1995. Immunity to intracellular microbial pathogens. Immunol Today 16: 338-342.
93. Khalifa KS, Roth A, Roth B, Arasteh KN, Janitschke K 1994. Value of PCR for evaluating occurrence of parasitemia in immunocompromised patients with cerebral and extracerebral toxoplasmosis. J Clin Microbiol 32: 2813-2819.
94. Kirchoff LV 1993 American trypanosomiasis (Chagas' disease) - A tropical disease now in the United States. N Engl J Med 329: 639-644.
95. Kohl S, Pickering L K, Frankel LS, Yalger RG 1982. Reactivation of Chagas disease during therapy of acute lymphocytic leukemia. Cancer 50: 827-828.
96. Kovacs JA 1992. Efficacy of atovaquone in treatment of toxoplasmosis in patients with AIDS. Lancet 340: 637.
97. Krick JA, Remington JS 1978. Toxoplasmosis in adult - An overview. N Engl J Med 298: 550-553.
98. La Rosa R, Pineda JA , Delgado J, Macias J, Morillas F, Martin Sanchez J, Leal M, Sanchez Quijano A, Lissen E 2001. Influence of highly active antiretroviral therapy on the outcome of subclinical visceral leishmaniasis in human immunodeficiency virus infected patients. Clin Infect Dis 32: 633-635.
99. Letillois MF, Laigle V, Santoro F, Micoud M, Chumpitazi BFF 1995. Toxoplasma gondii surface antigen-1 in sera of HIV-infected patients as an indicator of reactivated toxoplasmosis. Eur J Clin Microb Infect Dis 14: 899-903.
100. Liarte DB, Mendonça IL, Luz FCO, Abreu EAS, Mello GWS, Farias TJC, Ferreira AFB, Willington MA, Costa CHN 2001. QBC® for the diagnosis of human and canine American visceral leishmaniasis: preliminary data. Rev Soc Bras Med Trop 34: 577-581.
101. Lopez-Blanco AO, Cavalli NH, Jasovich A, Gotlieb D, Gonzalez Cappa S 1992. Chagas' disease and kidney transplantation - follow-up of nine patentes for 11 years Transplantation 24: 3089-3090.
102. Lopez-Velez R, Perez Molina JA, Guerrero A, Baquero F, Villarrubia J, Escribano L, Bellas C, Perez-Carrol F, Alvar J 1998. Clinicoepidemiologic caracteristics, prognostic factors and survival analysis of patients coinfected with human immunodeficiency virus and Leishmania in an area of Madrid, Spain. Am J Trop Med Hyg 58: 436-443.
103. Luders C, Caetano MA, Ianhez LE, Fonseca JA, Sabbaga E 1992. Renal transplantation in patients with Chagas' disease: a long-term follow-up. Transplantation 24: 1878-1879.
104. Luft BJ, Remington JS 1988. Toxoplasmosis encephalitis. J Infect Dis 157: 1-6.
105. Luft BJ, Brooks RG, Conley FK, McCabe RE, Remington JS 1984. Toxoplasmic encephalitis in patients with acquired immunodeficiency syndrome. JAMA 252: 913-917.
106. Luft BJ, Conley F, Remington JS, Laverdiere M, Levine JF, Strandberg DA, Wagner KF, Craven PC, File T, Tice N, Carpentier FM 1983. Outbreak of central-nervous-system toxoplasmosis in western Europe and North America. N Eng J Med 1: 781-783.
107. Luft BJ, Hafner R, Korzun AH, Leport C, Antoniskis D, Bosler E, Bourland D, Uttamchandani R, Fuhrer J, Jacobson J, Morlat P, Vilde JL, Remington JS 1993. Toxoplasmic encephalitis in patients with the acquired immunodeficiency syndrome. N Eng J Med 329: 995-1000.
108. Machado ES, Braga MP, Da Cruz AM, Coutinho SG, Vieira ARM, Rutowitsch MS, Cussi-Maya T, Grimaldi G, Menezes JÁ 1992. Disseminated american mucocutaneaus leishmaniasis caused by Leishmania braziliensis braziliensis in a patient with AIDS: a case report. Mem Inst Oswaldo Cruz 87: 481-492.
109. Manabe YC, Clark DP, Moore RD, Lumadue JA, Dahlman HR, Belitsos PC 1998. Cryptospondiosis in patientes with AIDS: correlates of disease and survival. Clin Infect Dis 27: 536-542.
110. McCabe RE, Remington JS, Araujo FG 1985. "In vivo" and "in vitro" effects of cyclosporin A on Tiypamosoma cruzi. Am J Trop Med Hyg 34: 861-865.
111. Mechert PMC, Chambo JG, Langrens RP 1988. Modification of the pattern of infection and evolution of cardyopatology in experimental Chagas' disease after treatment with immunosupressive trypanocidal drugs. Medicina (Buenos Aires) 48: 7-11.
112. Medrano FJ, Hernandez Quero J, Jimenez E, Pineda J, Rivero A, Sanchez Quijano A, LissenE 1993. Visceral leishmaniasis in HIV-1 infected individuals: a common opportunistic infection in Spain? AIDS 6: 1499-1503.
113. Monteverde DA, Taratuto AL, Lucatelli N 1976. Meningoencefalitc chagásica aguda em pacientes imunossuprimidos. Rev Neurol Arg 2: 260- 266.
114. Moore AC, Herwauldt BL, Craun GF 1993. Surveillance for waterborne disease outbreaks, United States, 1991-1992. MMWR 42 (Suppl. 55-5): 1-22.
115. Moos DM, Bennett SN, Arrowood MJ, Wahlquist SP, Lammie PJ 1998. Enzyme-linked immunoelectrotransfer blot analysis of a cryptosporidiosis outbreak on a United States Coast Guard cutter. Am J Trop Med Hyg 58: 110-118.
116. Morgado MG, Barcellos C, Pina MF, Bastos FI 2000. Human immunodeficiency virus/acquired immnodefaiciency syndrome and tropical diseases: a Brazilian perspective. Mem Inst Oswaldo Cruz 95: 145-151.
117. Morrow RH, Colebunders RL, Chin V 1989. Interactions of HIV infection with endemic tropical diseases. AIDS 3: 579-587.
118. Moura H, Fernandes O, Viola JPB 1989. Enteric parasites and HIV infection: ocurrence in AIDS patients in Rio de Janeiro, Brazil. Mem Inst Oswaldo Cruz 84: 527-533.
119. Müller F, Moskophidis M 1983. Estimation of the local production of antibodies to Treponema pallidum in the central nervous system of patients with neurosyphils. Brit J Vener Dis 59: 80-84.
120. Navin TR, Roberto RR, Juranela DD, Lempakarnjanrat K, Mortenson EW, Clower JR, Yercott JR, Taclindo C, Steurer F, Allain D 1985. Human and sylvatic Trypanosoma cruzi infection in California. Am J Publ Health 75: 366-369.
121. Nickerson P, Orr P, Schroeder ML, Sekla L, Johnston JB 1989 Transfusion associated Trypanosoma cruzi infection in a non-endemic area. Ann Intern Med 111: 851-853.
122. Nishioka SA, Ferreira MS, Rocha A, Borges AS 1993. Reactivation of Chagas' disease successfully treated with benznidazole in a patients with acquired immunodeficiency syndrome. Mem Inst Oswaldo Cruz 88: 493-496.
123. Oddo' D, Casanova M, Acuna G, Ballesteros J, Morales B 1992. Acute Chagas' disease (typanosomiasis americana) in acquired immunodeficiency: report two cases. Hum Pathol 23: 42-44.
124. Drefice G, Carried PB, De Marinis T, Troisi E, Farace A, Noice S, Buscaino GA 1990. Use of the intrathecal synthesis of antitoxoplasma antibodies in the diagnostic assessment and in the follow-up of AIDS patients with cerebral toxoplasmosis. Acta Neurol 12: 79-81.
125. Pan American Health Organization 1990. Health conditions in the Americas, Scientific Publication 524, Vol. 1, Washington, DC, p. 160.
126. Parker SJ, Roberts CW, Alexander J 1991. CD8+ T cells are the major lymphocyte subpopulation envolved in the protective immune response to Toxoplasma gondii in mice. Clin Exp Immunol 84: 207-212.
127. Parmley SF, Goebel FD, Remington JS 1992. Detection of Toxoplasma gondii in cerebrospinal fluid from AIDS patients by polymerase chain reaction. J Clin Microbiol 30: 3000-3002.
128. Pedersen C, Danner S, Lazzarin A 1996. Incidence of cryptosporidiosis among European AIDS patients. Genitourin Med 72: 128-131.
129. Piarroux R, Gambarelli F, Dumon H, Fontes M, Fontes M, Dunan S, Mary C, Toga B, Quilici N 1994. Comparison of PCR with direct examination of bone marrow, myeloculture and serology for diagnosis of visceral leishmaniasis in immunocompromised patients. J Clin Microbiol 33: 746-749.
130. Pinon JM, Thoannes H, Pouletty PH, Poirriez H, Damiens J, Pelletier P 1986. Detection of IgA specific for toxoplasmosis in serum and cerebrospinal fluid using a non-enzymatic IgA-capture assay. Diag Immunol 4: 223-227.
131. Pizzi T, De Croizet VA, Smoky G, Diaz M 1982. Enfermedad de Chagas en um paciente com transplante renal y tratamento imunosupresor. Rev Med Chile 110: 1207-211.
132. Porter SB, Sande MA 1992. Toxoplasmosis of the central nervous system in the acquired immunodeficiency syndrome. New Eng J Med 327: 1643-1648.
133. Potasman I, Resnick L, Luft BJ, Remington J 1988. Intrathecal production of antibodies against Toxoplasma gondii in patients with toxoplasmic encephalitis and the acquired immunodeficiency syndrome (AIDS). Ann Inter Med 108: 49-51.
134. Pozio E, Rezza G, Boschini A, Boschini A, Pezzotti P, Tamburrini A, Rossi P 1997. Clinical cryptosporidiosis and human immunodeficiency virus (HIV) - induced immunossupression: findings from a longitudinal study of HIV - positive and HIV-negative former infection drug users. J Infect Dis 176: 969-975.
135. Queiroz AC 1973. Tumorlike lesion of the brain caused by Trypanosoma cruzi. Am J Trop Med Hyg 22: 473-476.
136. Rabelo A, Andrade MO, Disch J 1998. Coinfecção Leishmania/HIV. Rev Soc Bras Med Trop 31: 81-91.
137. Reiber H 1980. The discrimination between different blood-CSF barrier dysfunctions and inflammatory reactions of the CNS by a recent evaluation graph for the protein profile of cerebrospinal fluid. J Neurol 224: 89-99.
138. Ribera E, Ocana I, Otero J, Cortes E, Gasser I, Pahissa A 1996. Prophylaxis of visceral leishmaniasis in human immunodeficiency virus infected patients. Am J Med 100: 496-501.
139. Richardson AJ, Frankenberg RA, Buck AC 1991. An outbreak of waterborne cryptosporidiosis in Swinton and Oxfordshire. Epidemiol Infect 107: 485-495.
140. Rivero I, Moravenik M, Morales J, Gomez M, De Rosas JM 1974. Chagas disease - another hazard in acute leukemia. N Engl J Med 290: 285.
141. Rocha A, Ferreira MS, Nishioka SA, Silva M, Burgarelli MKN, Silva AM, Moura LP, Ugrinovich R, Raffin C 1993. Trypanosoma cruzi meningoencephalitis in a patient with acquired immunodeficiency syndrome. Rev Inst Med Trop São Paulo 35: 205-208.
142. Rocha, A. Menezes ACO, Silva AM, Ferreira MS, Nishioka AS, Burgarelli MKN, Almeida E, Turcato JR G, Metz K, Lopes ER 1994. Pathology of patients with Chagas disease and acquired immunodeficiency syndrome. Rev Inst Med Trop São Paulo 35: 205-208.
143. Rosenthal E, Marty P, Faraut-Gambarelli F 1999. Epidemiologie de la coinfection Leishmania/VIH dans le sud de la France entre 1986 et 1997. Rev Med Interne 20: 73.
144. Rosenthal E, Marty P, Guidice P, Pradier P, Ceppi C. Gastant JA, Fichoux Y, Cassuto JP 2000. HIV and Leishmania coinfection: a review of 91 cases with focus on atypical locations of Leishmania Clin Infect Dis 3: 1093-1095.
145. Rosenthal E, Marty P, Poizot Martin I, Reynnes J, Pratlong F, Lafeuilla de A, Jaubert D, Boulat O, Dereure J, Gambaretli F, Gastant JA, Dujardin P, Dellamonica P, Cassuto JP 1995 Visceral leishmaniases and HIV-1 coinfection in southern France. Trans R Soc Trop Med Hyg 89: 159-162.
146. Ruskin J, Remington JS 1976. Toxoplasmosis in the compromised host. Ann Int Med 84: 193-199.
147. Saba J, MorlaT P, Raffi F 1993. Pyrimetamineplusazithromycin for treatment of acute toxoplasmic encephalitis in patients with AIDS. Eur J Clin Microbiol Infect Dis 12: 853.
148. Sartori AMC, Shikanai Yasuda MA, Amato NetoV, Lopes MH 1998. Follow up of 18 patients with human immunodeficient virus infection and chronic Chagas' disease, with reactivation of Chagas' disease causing cardiac disease in three patients. Clin Infect Dis 26: 177-179.
149. Sims TA, Talbot IC 1989. An electron microscope and immunohistochemical study of intracellular location of Toxoplasma gondii cysts within the brains of mice with congenital toxoplasmosis. Braz J Exper Pathol 70: 317-325.
150. Sinagra A, Riarte A, Lauricella M, Segurra EL, 1993. Reactivation of experimental chronic T. cruzi infection after immunosupressive treatment by cyclosporive A and betanetasone. Transplantation 55: 1431-1434.
151. Sorvillo F, Beall G, Turner PA, Beer VL, Kovacs AA, Kraus P 1998. Seasonality and factors associated with cryptosporidiosis among individuals with HIV infection. Epidemol Infect 121: 197-204.
152. Stolf NAG, Higushi L, Bochi E, Bellotti G, Auler JOC, Uip D, Amato Neto V, Pillegi F, Jatene A D 1987. Heart transplantation in patents with Chagas disease cardiomyopathy. J Heart Transpl 6: 307-312.
153. Tirard V, Niel G, Rosenheim M, Katlama C, Ciceron L, Ogunkolade W, Danis M, Genrilini M 1991. Diagnosis of toxoplasmosis in patients with AIDS by isolation of the parasite from the blood. New Eng J Meet 324: 634.
154. Tschirhart D, Klatt EC 1988. Disseminated toxoplasmosis in the acquired immnunodeficiency syndrome. Arc Path Labor Med 112: 1237-1241.
155. Van Thiel PH 1966. The parasitology of toxoplasmosis in the central nervous system. Psych Neurol Neuroch 60: 7-13.
156. Wanderley DMV, Camargo LMA, Carvalho ME 1988. Doença de Chagas: registro de caso agudo transfusional. Rev Inst Med Trop São Paulo 30: 437-440.
157. Wanke C, Tuazon CU, Kovacs A, Dona T, Davis D, Barton N, Katz D, Lunde M, Levy C, Conleu FK, Lane HC, Fauci AS, Masur H 1987. Toxoplasma encephalitis in patients with acquired immune deficiency syndrome: diagnosis and response to therapy. Am J Trop Med Hyg 36: 509-516.
158. Weiss LM, Udem AS, Tanowitz H, Wittner M 1988. Western Blot analysis of the antibody response of patients with AIDS and Toxoplasma encephalitis: antigenic diversity among Toxoplasma strains. J Infect Dis 157: 7-13.
159. Wong B, Gold JWM, Brown AE, Lange M, Fried R, Grieco M, Mildvan D, Giron J, Tapper ML, Lerner CW, Armstrong D 1984. Central-nervous-system toxoplasmosis in homossexual men and parenteral drug abusers. Ann Int Med 100: 36-42.
160. Young LS 1981. Infection in the compromised host. Hosp Pract 16: 73-84.
161. Zangerle R, Allerberger F, Pohl P, Fritsch P, Dierich MP 1991. High risk of developing toxoplasmic encephalitis in AIDS patients seropositive to Toxoplasma gondii. Med Microb Immunol 180: 59-66.