Suppression of CCR5- but not CXCR4-tropic HIV-1 in lymphoid tissue by human herpesvirus 6

Nature Medicine

Volumn 7, Issue 11, 2001, Pages 1232-1235

  Grivel, Jean Charles ^a   Ito, Yoshinori ^a   Fagà, Giovanni ^c   Santoro, Fabio ^c   Shaheen, Farida ^c   Malnati, Mauro S ^d   Fitzgerald, Wendy ^b   Lusso, Paolo ^c,d   Margolis, Leonid ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; RANTES;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; DISEASE COURSE; HUMAN; HUMAN HERPESVIRUS 6; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; LYMPHOID TISSUE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SYNTHESIS; TISSUE DISTRIBUTION; VIRUS PATHOGENESIS; VIRUS REPLICATION;

CULTURE TECHNIQUES; HERPESVIRUS 6, HUMAN; HIV INFECTIONS; HIV-1; HUMANS; LYMPHOID TISSUE; RANTES; RECEPTORS, CCR5; RECEPTORS, CXCR4; ROSEOLOVIRUS INFECTIONS; VIRUS REPLICATION;

HERPESVIRIDAE; HUMAN HERPESVIRUS 6; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0035168719     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm1101-1232     Document Type: Article

References (31)

1. Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism and disease
2. Distinct replicative and cytopathic characteristics of human immunodeficiency virus isolates
3. Association between biological properties of human immunodeficiency virus variants and risk for AIDS and AIDS mortality
4. Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: Progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population
5. Viral phenotype and severity of HIV-1 infection: Are children different from adults?
6. + cell depletion and progression to AIDS
7. Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype
8. In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression
9. Change in coreceptor use coreceptor use correlates with disease progression in HIV-1-infected individuals
10. + T cell decline in viva
11. Conversion rate towards a syncytium-inducing (SI) phenotype during different stages of human immunodeficiency virus type 1 infection and prognostic value of SI phenotype for survival after AIDS diagnosis
12. Human herpesvirus 6 in AIDS
13. Infection of human tonsil histocultures: A model for HIV pathogenesis
14. + T cell depletion and virus syncytium-inducing/non-syncytium-inducing phenotype in histoculture inoculated with laboratory strains and patient isolates of HIV type 1
15. CCR5- and CXCR4-tropic HIV-1 are equally cytopathic for their T-cell targets in human lymphoid tissue
16. + T cells
17. Isolation of a new virus HBLV in patients with lymphoproliferative disorders
18. Real-time quantitative PCR for human herpesvirus 6 DNA
19. Determinants of entry cofactor utilization and tropism in a dualtropic human immunodeficiency virus type 1 primary isolate
20. Preferential coreceptor utilization and cytopathicity by dualtropic HIV-1 in human lymphoid tissue ex vivo
21. + T cells of HIV-infected individuals is regulated by a balance between the viral suppressive effects of endogenous β-chemokines and the viral inductive effects of other endogenous cytokines
22. Blockade of CC chemokine receptor 5 (CCRS)-tropic human immunodeficiency virus-1 replication in human lymphoid tissue by CC chemokines
23. Enhancement of human immunodeficiency virus type 1 infection by the CC-chemokine RANTES is independent of the mechanism of virus-cell fusion
24. + T cells: Role of signal transduction
25. Dichotomous effects of β-chemokines on HIV replication in monocytes and monocyte-derived macrophages
26. Increased replication of T-cell-tropic HIV strains and CXC-chemokine receptor-4 induction in T cells treated with macrophage inflammatory protein (MIP)-1α, MIP-1β and RANTES β-chemokines
27. Utilization of chemokine receptors, orphan receptors, and herpesvirus-encoded receptors by diverse human and simian immunodeficiency viruses
28. Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation
29. RANTES binding and down-regulation by a novel human herpesvirus-6 β chemokine receptor
30. Effect of co-infection with GB virus C on survival among patients with HIV infection
31. HIV-1 suppression during acute scrub-typhus infection