Evidence that vitamin D3 promotes mast cell-dependent reduction of chronic UVB-induced skin pathology in mice

Journal of Experimental Medicine

Volumn 207, Issue 3, 2010, Pages 455-463

  Biggs, Lisa ^a   Yu, Chunping ^a,b   Fedoric, Boris ^a   Lopez, Angel F ^a,b   Galli, Stephen J ^c   Grimbaldeston, Michele A ^a,b  

^a CENTRE FOR CANCER BIOLOGY   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLECALCIFEROL; IMMUNOMODULATING AGENT; INTERLEUKIN 10; MESSENGER RNA; VITAMIN D RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; EPIDERMIS HYPERPLASIA; FEMALE; HISTOPATHOLOGY; MAST CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION INJURY; SKIN DISEASE; SKIN INFLAMMATION; SKIN TRANSPLANTATION; SKIN ULCER; ULTRAVIOLET B RADIATION; UPREGULATION;

ANIMALS; BONE MARROW CELLS; CALCITRIOL; CELL CULTURE TECHNIQUES; CELLS, CULTURED; CHOLECALCIFEROL; CYTOKINES; INFLAMMATION; INTERLEUKIN-10; MAST CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PIGMENTATION; RECEPTORS, CALCITRIOL; SKIN; SKIN TRANSPLANTATION; ULTRAVIOLET RAYS;

EID: 77949508194     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20091725     Document Type: Article

References (31)

1. Alard, P., H. Niizeki, L. Hanninen, and J.W. Streilein. 1999. Local ultraviolet B irradiation impairs contact hypersensitivity induction by triggering release of tumor necrosis factor-alpha from mast cells. Involvement of mast cells and Langerhans cells in susceptibility to ultraviolet B. J. Invest. Dermatol. 113:983-990. doi:10.1046/j.1523-1747.1999.00772.x
2. Baroni, E., M. Biffi, F. Benigni, A. Monno, D. Carlucci, G. Carmeliet, R. Bouillon, and D. D'Ambrosio. 2007. VDR-dependent regulation of mast cell maturation mediated by 1,25-dihydroxyvitamin D3. J. Leukoc. Biol. 81:250-262. doi:10.1189/jlb.0506322
3. Beissert, S., A. Schwarz, and T. Schwarz. 2006. Regulatory T cells. J. Invest. Dermatol. 126:15-24. doi:10.1038/sj.jid.5700004
4. + T cells to enhance the development of Th2 cells. J. Immunol. 167:4974-4980.
5. Bouillon, R., G. Carmeliet, L. Verlinden, E. van Etten, A. Verstuyf, H.F. Luderer, L. Lieben, C. Mathieu, and M. Demay. 2008. Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr. Rev. 29:726-776. doi:10.1210/er.2008-0004
6. v. J. Cell. Physiol. 73:25-30. doi:10.1002/jcp.1040730104
7. Ellison, T.I., M.K. Smith, A.C. Gilliam, and P.N. MacDonald. 2008. Inactivation of the vitamin D receptor enhances susceptibility of murine skin to UV-induced tumorigenesis. J. Invest. Dermatol. 128:2508-2517. doi:10.1038/jid.2008.131
8. Galli, S.J., M. Grimbaldeston, and M. Tsai. 2008. Immunomodulatory mast cells: negative, as well as positive, regulators of immunity. Nat. Rev. Immunol. 8:478-486. doi:10.1038/nri2327
9. Galli, S.J., J. Kalesnikoff, M.A. Grimbaldeston, A.M. Piliponsky, C.M. Williams, and M. Tsai. 2005. Mast cells as "tunable" effector and immunoregulatory cells: recent advances. Annu. Rev. Immunol. 23:749-786. doi:10.1146/annurev.immunol.21.120601.141025
10. Gorman, S., L.A. Kuritzky, M.A. Judge, K.M. Dixon, J.P. McGlade, R.S. Mason, J.J. Finlay-Jones, and P.H. Hart. 2007. Topically applied 1,25-dihydroxyvitamin D3 enhances the suppressive activity of CD4+CD25+ cells in the draining lymph nodes. J. Immunol. 179:6273-6283.
11. Grimbaldeston, M.A., S. Nakae, J. Kalesnikoff, M. Tsai, and S.J. Galli. 2007. Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B. Nat. Immunol. 8:1095-1104.
12. Hart, P.H., M.A. Grimbaldeston, G.J. Swift, E.K. Hosszu, and J.J. Finlay-Jones. 1999. A critical role for dermal mast cells in cis-urocanic acidinduced systemic suppression of contact hypersensitivity responses in mice. Photochem. Photobiol. 70:807-812. doi:10.1111/j.1751-1097.1999.tb08286.x
13. Hart, P.H., M.A. Grimbaldeston, G.J. Swift, A. Jaksic, F.P. Noonan, and J.J. Finlay-Jones. 1998. Dermal mast cells determine susceptibility to ultraviolet B-induced systemic suppression of contact hypersensitivity responses in mice. J. Exp. Med. 187:2045-2053. doi:10.1084/jem.187.12.2045
14. Hart, P.H., S.L. Townley, M.A. Grimbaldeston, Z. Khalil, and J.J. Finlay-Jones. 2002. Mast cells, neuropeptides, histamine, and prostaglandins in UV-induced systemic immunosuppression. Methods. 28:79-89. doi:10.1016/S1046-2023(02)00201-3
15. Kato, S., M.S. Kim, K. Yamaoka, and R. Fujiki. 2007. Mechanisms of transcriptional repression by 1,25(OH)2 vitamin D. Curr. Opin. Nephrol. Hypertens. 16:297-304. doi:10.1097/MNH.0b013e3281c55f16
16. Khalil, Z., S.L. Townley, M.A. Grimbaldeston, J.J. Finlay-Jones, and P.H. Hart. 2001. cis-Urocanic acid stimulates neuropeptide release from peripheral sensory nerves. J. Invest. Dermatol. 117:886-891. doi:10.1046/j.0022-202x.2001.01466.x
17. Kirnbauer, R., A. Köck, P. Neuner, E. Förster, J. Krutmann, A. Urbanski, E. Schauer, J.C. Ansel, T. Schwarz, and T.A. Luger. 1991. Regulation of epidermal cell interleukin-6 production by UV light and corticosteroids. J. Invest. Dermatol. 96:484-489. doi:10.1111/1523-1747.ep12470181
18. Kligman, L.H. 1996. The hairless mouse model for photoaging. Clin. Dermatol. 14:183-195. doi:10.1016/0738-081X(95)00154-8
19. Lehmann, B. 2005. The vitamin D3 pathway in human skin and its role for regulation of biological processes. Photochem. Photobiol. 81:1246-1251. doi:10.1562/2005-02-02-IR-430
20. Lu, L.F., E.F. Lind, D.C. Gondek, K.A. Bennett, M.W. Gleeson, K. Pino-Lagos, Z.A. Scott, A.J. Coyle, J.L. Reed, J. Van Snick, et al. 2006. Mast cells are essential intermediaries in regulatory T-cell tolerance. Nature. 442:997-1002.
21. Melnikova, V.O., and H.N. Ananthaswamy. 2005. Cellular and molecular events leading to the development of skin cancer. Mutat. Res. 571:91-106.
22. Metz, M., V. Lammel, B.F. Gibbs, and M. Maurer. 2006. Inflammatory murine skin responses to UV-B light are partially dependent on endothelin-1 and mast cells. Am. J. Pathol. 169:815-822. doi:10.2353/ajpath.2006.060037
23. Moro, J.R., M. Iwata, and U.H. von Andriano. 2008. Vitamin effects on the immune system: vitamins A and D take centre stage. Nat. Rev. Immunol. 8:685-698. doi:10.1038/nri2378
24. sh) mice interrupts Corin and manifests as hematopoietic and cardiac aberrancy. Am. J. Pathol. 173:1693-1701. doi:10.2353/ajpath.2008.080407
25. Nishigori, C., D.B. Yarosh, S.E. Ullrich, A.A. Vink, C.D. Bucana, L. Roza, and M.L. Kripke. 1996. Evidence that DNA damage triggers interleukin 10 cytokine production in UV-irradiated murine keratinocytes. Proc. Natl. Acad. Sci. USA. 93:10354-10359. doi:10.1073/pnas.93.19.10354
26. Noonan, F.P., and E.C. De Fabo. 1992. Immunosuppression by ultraviolet B radiation: initiation by urocanic acid. Immunol. Today. 13:250-254. doi:10.1016/0167-5699(92)90005-R
27. W-sh/W-sh mice. Am. J. Pathol. 176:926-938. doi:10.2353/ajpath.2010.090342
28. Townley, S.L., M.A. Grimbaldeston, I. Ferguson, R.A. Rush, S.H. Zhang, X.F. Zhou, J.M. Conner, J.J. Finlay-Jones, and P.H. Hart. 2002. Nerve growth factor, neuropeptides, and mast cells in ultraviolet-B-induced systemic suppression of contact hypersensitivity responses in mice. J. Invest. Dermatol. 118:396-401. doi:10.1046/j.0022-202x.2001.01679.x
29. van Etten, E., and C. Mathieu. 2005. Immunoregulation by 1,25-dihydroxyvitamin D3: basic concepts. J. Steroid Biochem. Mol. Biol. 97:93-101.
30. Wolf, P., H. Maier, R.R. Müllegger, C.A. Chadwick, R. Hofmann-Wellenhof, H.P. Soyer, A. Hofer, J. Smolle, M. Horn, L. Cerroni, et al. 2000. Topical treatment with liposomes containing T4 endonuclease V protects human skin in vivo from ultraviolet-induced upregulation of interleukin-10 and tumor necrosis factor-alpha. J. Invest. Dermatol. 114:149-156. doi:10.1046/j.1523-1747.2000.00839.x
31. Yamazaki, F., H. Okamoto, H. Miyauchi-Hashimoto, Y. Matsumura, T. Itoh, K. Tanaka, T. Kunisada, and T. Horio. 2004. XPA gene-deficient, SCF-transgenic mice with epidermal melanin are resistant to UV-induced carcinogenesis. J. Invest. Dermatol. 123:220-228. doi:10.1111/j.0022-202X.2004.22710.x