Molecular surveillance of Plasmodium vivax dhfr and dhps mutations in isolates from Afghanistan

Malaria Journal

Volumn 9, Issue 1, 2010, Pages

  Zakeri, Sedigheh ^a   Afsharpad, Mandana ^a   Ghasemi, Faezeh ^a   Raeisi, Ahmad ^b   Safi, Najibullah ^c   Butt, Waqar ^d   Atta, Hoda ^e   Djadid, Navid D ^a  

^a PASTEUR INSTITUTE OF IRAN   (Iran)

^b MINISTRY OF HEALTH AND MEDICAL EDUCATION   (Iran)

^c Ministry of Public Health   (Afghanistan)

^d Office of the WHO Representative   (Afghanistan)

^e WHO/EMRO   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; DIHYDROPTEROATE SYNTHASE; FANSIDAR; GENOMIC DNA; ANTIMALARIAL AGENT; PYRIMETHAMINE; SULFADOXINE; SULFADOXINE-PYRIMETHAMINE;

AFGHANISTAN; ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; DISEASE SURVEILLANCE; DNA POLYMORPHISM; DRUG RESISTANCE; ENDEMIC DISEASE; GENE MUTATION; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALARIA; NONHUMAN; PARASITE ISOLATION; PLASMODIUM VIVAX; SINGLE NUCLEOTIDE POLYMORPHISM; ANIMAL; DNA SEQUENCE; DRUG COMBINATION; FEMALE; GENETICS; ISOLATION AND PURIFICATION; MALE; MOLECULAR GENETICS; MUTATION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

AFGHANISTAN; ANIMALS; ANTIMALARIALS; DIHYDROPTEROATE SYNTHASE; DRUG COMBINATIONS; FEMALE; HAPLOTYPES; HUMANS; MALE; MOLECULAR SEQUENCE DATA; MUTATION; PLASMODIUM VIVAX; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; PYRIMETHAMINE; SEQUENCE ANALYSIS, DNA; SULFADOXINE; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 77949439959     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-9-75     Document Type: Article

References (35)

1. The neglected burden of Plasmodium vivax malaria. K Mendis BJ Sina P Marchesini R Carter, Am J Trop Med Hyg 2001 64 1-2 Suppl 97 106 11425182
2. Drug resistance among malaria and other parasites. LM Barat PB Bloland, Infect Dis Clin North Am 1997 11 969 987 10.1016/S0891-5520(05)70400-1 9421710
3. Evidence for different mechanisms of chloroquine resistance in 2 Plasmodium species that cause human malaria. T Nomura JM Carlton JK Baird HA Del Portillo DJ Fryauff D Rathore DA Fidock X Su WE Collins TF McCutchan JC Wootton TE Wellems, J Infect Dis 2001 183 1653 1661 10.1086/320707 11343215
4. Multidrug-resistant Plasmodium vivax Associated with severe and fatal malaria: A prospective study in Papua, Indonesia. E Tjitra NM Anstey P Sugiarto N Warikar E Kenangalem M Karyana DA Lampah RN Price, PLoS Med 2008 5 128 10.1371/journal.pmed.0050128 18563962
5. Demographic risk factors for severe and fatal vivax and falciparum malaria among hospital admissions in northeastern Indonesian Papua. MJ Barcus H Basri H Picarima C Manyakori Sekartuti I Elyazar MJ Bangs JD Maguire JK Baird, Am J Trop Med Hyg 2007 77 984 991 17984364
6. Genetic diversity of Plasmodium vivax pvcsp and pvmsp1 in Guyana, South America. JA Bonilla L Validum R Cummings CJ Palmer, Am J Trop Med Hyg 2006 75 830 835 17123973
7. Mechanisms of resistance of malaria parasites to antifolates. A Gregson CV Plowe, Pharmacol Rev 2005 57 117 145 10.1124/pr.57.1.4 15734729
8. Novel point mutations in the dihydrofolate reductase gene of Plasmodium vivax: evidence for sequential selection by drug pressure. M Imwong S Pukrittayakamee L Rénia F Letourneur JP Charlieu U Leartsakulpanich S Looareesuwan NJ White G Snounou, Antimicrob Agents Chemother 2003 47 1514 1521 10.1128/AAC.47.5.1514-1521.2003 12709316
9. The mode of action and the mechanism of resistance to antimalarial drugs. SJ Foote AF Cowman, Acta Trop 1994 56 157 171 10.1016/0001-706X(94)90061-2 8203302
10. Association of genetic mutations in Plasmodium vivax dhfr with resistance to sulfadoxine-pyrimethamine: geographical and clinical correlates. M Imwong S Pukrittakayamee S Looareesuwan G Pasvol J Poirreiz NJ White G Snounou, Antimicrob Agents Chemother 2001 45 3122 3127 10.1128/AAC.45.11.3122-3127.2001 11600366
11. Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum. T Triglia JG Menting C Wilson AF Cowman, Proc Natl Acad Sci USA 1997 94 13944 13949 10.1073/pnas.94.25.13944 9391132
12. Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance. CV Plowe JF Cortese A Djimde OC Nwanyanwu WM Watkins PA Winstanley JG Estrada-Franco RE Mollinedo JC Avila JL Cespedes D Carter OK Doumbo, J Infect Dis 1997 176 1590 1596 10.1086/514159 9395372
13. Therapeutic efficacies of artesunate-sulfadoxine-pyrimethamine and chloroquine-sulfadoxine-pyrimethamine in vivax malaria pilot studies: relationship to Plasmodium vivax dhfr mutations. E Tjitra J Baker S Suprianto Q Cheng NM Anstey, Antimicrob Agents Chemother 2002 46 3947 3953 10.1128/AAC.46.12.3947-3953.2002 12435700
14. Sequence variations in the Plasmodium vivax dihydrofolate reductase-thymidylate synthase gene and their relationship with pyrimethamine resistance. PE de Pécoulas R Tahar T Ouatas A Mazabraud LK Basco, Mol Biochem Parasitol 1998 92 265 273 10.1016/S0166-6851(97)00247-8 9657331
15. Antifolates can have a role in the treatment of Plasmodium vivax. VN Hawkins H Joshi K Rungsihirunrat K Na-Bangchang CH Sibley, Trends Parasitol 2007 23 213 222 10.1016/j.pt.2007.03.002 17368986
16. Plasmodium vivax dhfr and dhps mutations in isolates from Madagascar and therapeutic response to sulphadoxine-pyrimethamine. C Barnadas M Tichit C Bouchier A Ratsimbasoa L Randrianasolo R Raherinjafy M Jahevitra S Picot D Ménard, Malar J 2008 7 35 10.1186/1475-2875-7-35 18302746
17. Ministry of Health Afghanistan. http://htpp://www.emro.who.int/ afghanistan/pdf/nmsp-08-013
18. Detection of high prevalence of mixed Plasmodium falciparum and P. vivax infections by nested-PCR in Pakistan and Iran but not in Afghanistan. S Zakeri Q Kakar F Ghasemi A Raeisi W Butt N Safi M Afsharpad MS Memon S Gholizadeh M Salehi H Atta G Zamani ND Djadid, Indian Journal of Medical Research 2010
19. High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reaction. G Snounou S Viriyakosol XP Zhu W Jarra L Pinheiro VE do Rosario S Thaithong KN Brown, Mol Biochem Parasitol 1993 61 315 320 10.1016/0166-6851(93)90077-B 8264734
20. Limited polymorphism in the dihydropteroate synthetase gene (dhps) of Plasmodium vivax isolates from Thailand. M Imwong S Pukrittayakamee Q Cheng C Moore S Looareesuwan G Snounou NJ White NP Day, Antimicrob Agents Chemother 2005 49 4393 4395 10.1128/AAC.49.10.4393-4395.2005 16189131
21. Molecular characterization of antifolates resistance-associated genes, (dhfr and dhps) in Plasmodium vivax isolates from the Middle East. S Zakeri SR Motmaen M Afsharpad ND Djadid, Malar J 2009 8 20 10.1186/1475-2875-8-20 19175936
22. Prevalence of antimalarial drug resistance mutations in Plasmodium vivax and P. falciparum from a malaria-endemic area of Pakistan. L Khatoon FN Baliraine M Bonizzoni SA Malik G Yan, Am J Trop Med Hyg 2009 81 525 528 19706926
23. Sensitivity to antifolates and genetic analysis of Plasmodium vivax isolates from Thailand. K Rungsihirunrat K Na-Bangchang VN Hawkins M Mungthin CH Sibley, Am J Trop Med Hyg 2007 76 1057 1065 17556611
24. Plasmodium vivax dihydrofolate reductase point mutations from the Indian subcontinent. S Kaur SK Prajapati K Kalyanaraman A Mohmmed H Joshi VS Chauhan, Acta Trop 2006 97 174 180 10.1016/j.actatropica.2005.10.003 16310156 (Pubitemid 43087751)
25. Amino acid mutations in Plasmodium vivax DHFR and DHPS from several geographical regions and susceptibility to antifolate drugs. A Auliff DW Wilson B Russell Q Gao N Chen N Anh le J Maguire D Bell MT O'Neil Q Cheng, Am J Trop Med Hyg 2006 75 617 621 17038682
26. Genetic variations of the dihydrofolate reductase gene of Plasmodium vivax in Mandalay Division, Myanmar. BK Na HW Lee SU Moon TS In K Lin M Maung GT Chung JK Lee TS Kim Y Kong, Parasitol Res 2005 96 321 325 10.1007/s00436-005- 1364-0 15924223
27. Real-time PCR for dihydrofolate reductase gene single-nucleotide polymorphisms in Plasmodium vivax isolates. S Brega F de Monbrison C Severini R Udomsangpetch I Sutanto P Ruckert F Peyron S Picot, Antimicrob Agents Chemother 2004 48 2581 2587 10.1128/AAC.48.7.2581-2587.2004 15215112
28. Evaluation of sensitivity of Plasmodium vivax to chloroquine. M Nateghpour SA Sayedzadeh GhH Edrissian A Raeisi A Jahantigh A Motevalli-Haghi Gh Mohseni A Rahimi, Iranian J Publ Health 2007 36 60 63
29. Dihydrofolate reductase mutations in Plasmodium vivax from Indonesia and therapeutic response to sulfadoxine plus pyrimethamine. MD Hastings KM Porter JD Maguire I Susanti W Kania MJ Bangs CH Sibley JK Baird, J Infect Dis 2004 189 744 750 10.1086/381397 14767830
30. Allelic polymorphism in the Plasmodium vivax dihydrofolate reductase gene among Indian field isolates. SK Prajapati H Joshi N Valecha AM Reetha A Eapen A Kumar MK Das RS Yadav MA Rizvi AP Dash, Clin Microbiol Infect 2007 13 331 334 10.1111/j.1469-0691.2006.01639.x 17391393
31. Kinetic properties of dihydrofolate reductase from wild-type and mutant Plasmodium vivax expressed in Escherichia coli. R Tahar PE de Pécoulas LK Basco M Chiadmi A Mazabraud, Mol Biochem Parasitol 2001 113 241 249 10.1016/S0166-6851(01)00230-4 11295178
32. Pyrimethamine and WR99210 exert opposing selection on dihydrofolate reductase from Plasmodium vivax. MD Hastings CH Sibley, Proc Natl Acad Sci USA 2002 99 13137 13141 10.1073/pnas.182295999 12198181
33. Molecular markers for failure of sulfadoxine-pyrimethamine and chlorproguanil-dapsone treatment of Plasmodium falciparum malaria. JG Kublin FK Dzinjalamala DD Kamwendo EM Malkin JF Cortese LM Martino RA Mukadam SJ Rogerson AG Lescano ME Molyneux PA Winstanley P Chimpeni TE Taylor CV Plowe, J Infect Dis 2002 185 380 388 10.1086/338566 11807721
34. Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in Plasmodium falciparum: genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites. AM Nzila EK Mberu J Sulo H Dayo PA Winstanley CH Sibley WM Watkins, Antimicrob Agents Chemother 2000 44 991 996 10.1128/AAC.44.4.991-996.2000 10722502
35. Chlorproguanil-dapsone for treatment of drug-resistant falciparum malaria in Tanzania. T Mutabingwa A Nzila E Mberu E Nduati P Winstanley E Hills W Watkins, Lancet 2001 358 1218 1223 10.1016/S0140-6736(01)06344-9 11675058 (Pubitemid 33010845)