Basophil sensitivity through CD63 or CD203c is a functional measure for specific immunotherapy

Clinical and Molecular Allergy

Volumn 8, Issue , 2010, Pages

  Mikkelsen, Susan ^a   Bibby, Bo M ^b   Dolberg, Mette K B ^a   Dahl, Ronald ^a   Hoffmann, Hans J ^a,b  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALUTARD; CD203C ANTIGEN; CD63 ANTIGEN; LYMPHOCYTE ANTIGEN; UNCLASSIFIED DRUG;

ADULT; ANTIGEN EXPRESSION; ARTICLE; BASOPHIL; CLINICAL ARTICLE; CONTACT SENSITIZATION; CONTROLLED STUDY; EDEMA; FATIGUE; FEMALE; HEART BEAT; HUMAN; HUMORAL IMMUNITY; HYPERVENTILATION; IMMUNOTHERAPY; INSECT ALLERGY; LEUKOCYTE ACTIVATION; MAINTENANCE DRUG DOSE; MALE; NERVOUSNESS; PROTECTION; PRURITUS; SIDE EFFECT; URTICARIA; WASP;

EID: 77949437253     PISSN: None     EISSN: 14767961     Source Type: Journal    
DOI: 10.1186/1476-7961-8-2     Document Type: Article

References (30)

1. Oude Elberink JN, De Monchy JG, Heide S, Guyatt GH, Dubois AE. Venom immunotherapy improves health-related quality of life in patients allergic to yellow jacket venom. J Allergy Clin Immunol 2002, 110:174-182. 10.1067/mai.2002.125827, 12110838.
2. Canonica GW, Baena-Cagnani CE, Bousquet J, Bousquet PJ, Lockey RF, Malling HJ, Passalacqua G, Potter P, Valovirta E. Recommendations for standardization of clinical trials with Allergen Specific Immunotherapy for respiratory allergy. A statement of a World Allergy Organization (WAO) taskforce. Allergy 2007, 62:317-324. 10.1111/j.1398-9995.2006.01312.x, 17298350.
3. Ross RN, Nelson HS, Finegold I. Effectiveness of specific immunotherapy in the treatment of hymenoptera venom hypersensitivity: a meta-analysis. Clin Ther 2000, 22:351-358. 10.1016/S0149-2918(00)80039-9, 10963289.
4. Francis JN, James LK, Paraskevopoulos G, Wong C, Calderon MA, Durham SR, Till SJ. Grass pollen immunotherapy: IL-10 induction and suppression of late responses precedes IgG4 inhibitory antibody activity. J Allergy Clin Immunol 2008, 121:1120-1125. 10.1016/j.jaci.2008.01.072, 18374405.
5. Nopp A, Cardell LO, Johansson SG, Oman H. CD-sens: a biological measure of immunological changes stimulated by ASIT. Allergy 2009, 64:811-814. 10.1111/j.1398-9995.2008.01900.x, 19220221.
6. Hoffmann HJ, Bogebjerg M, Nielsen LP, Dahl R. Lysis with Saponin improves detection of the response through CD203c and CD63 in the basophil activation test after crosslinking of the high affinity IgE receptor FcepsilonRI. Clin Mol Allergy 2005, 3:10. 10.1186/1476-7961-3-10, 1201566, 15996266.
7. Kosnik M, Silar M, Bajrovic N, Music E, Korosec P. High sensitivity of basophils predicts side-effects in venom immunotherapy. Allergy 2005, 60:1401-1406. 10.1111/j.1398-9995.2005.00894.x, 16197472.
8. Plewako H, Wosinska K, Arvidsson M, Bjorkander J, Skov PS, Hakansson L, Rak S. Basophil interleukin 4 and interleukin 13 production is suppressed during the early phase of rush immunotherapy. Int Arch Allergy Immunol 2006, 141:346-353. 10.1159/000095461, 16940746.
9. Nagao M, Hiraguchi Y, Hosoki K, Tokuda R, Usui T, Masuda S, Yamaguchi M, Fujisawa T. Allergen-induced basophil CD203c expression as a biomarker for rush immunotherapy in patients with Japanese cedar pollinosis. Int Arch Allergy Immunol 2008, 146(Suppl 1):47-53. 10.1159/000126061, 18504407.
10. Nopp A, Johansson SG, Ankerst J, Bylin G, Cardell LO, Gronneberg R, Irander K, Palmqvist M, Oman H. Basophil allergen threshold sensitivity: a useful approach to anti-IgE treatment efficacy evaluation. Allergy 2006, 61:298-302. 10.1111/j.1398-9995.2006.00987.x, 16436137.
11. Knol EF, Mul FP, Jansen H, Calafat J, Roos D. Monitoring human basophil activation via CD63 monoclonal antibody 435. J Allergy Clin Immunol 1991, 88:328-338. 10.1016/0091-6749(91)90094-5, 1716273.
12. Buhring HJ, Seiffert M, Giesert C, Marxer A, Kanz L, Valent P, Sano K. The basophil activation marker defined by antibody 97A6 is identical to the ectonucleotide pyrophosphatase/phosphodiesterase 3. Blood 2001, 97:3303-3305. 10.1182/blood.V97.10.3303, 11342463.
13. Nouri-Aria KT, Irani AM, Jacobson MR, O'Brien F, Varga EM, Till SJ, Durham SR, Schwartz LB. Basophil recruitment and IL-4 production during human allergen-induced late asthma. J Allergy Clin Immunol 2001, 108:205-211. 10.1067/mai.2001.117175, 11496235.
14. Hoffmann HJ, Skjold T, Raithel M, Adolf K, Hilberg O, Dahl R. Response of respiratory flour allergics in an ingested flour challenge may involve plasmacytoid dendritic cells, CD25+ and CD152+ T cells. Int Arch Allergy Immunol 2006, 140:252-260. 10.1159/000093251, 16691032.
15. Blumberga G, Groes L, Haugaard L, Dahl R. Steroid-sparing effect of subcutaneous SQ-standardised specific immunotherapy in moderate and severe house dust mite allergic asthmatics. Allergy 2006, 61:843-848. 10.1111/j.1398-9995.2006.01088.x, 16792582.
16. R: A Language and Environment for Statistical Computing. , http://www.R-project.org
17. Greiner M. Two-graph receiver operating characteristic (TG-ROC): a Microsoft-EXCEL template for the selection of cut-off values in diagnostic tests. J Immunol Methods 1995, 185:145-146. 10.1016/0022-1759(95)00078-O, 7665897.
18. ROC analysis: web-based calculator for ROC curves. Baltimore. , http://www.jrocfit.org
19. Glencross D, Scott LE, Jani IV, Barnett D, Janossy G. CD45-assisted PanLeucogating for accurate, cost-effective dual-platform CD4+ T-cell enumeration. Cytometry 2002, 50:69-77. 10.1002/cyto.10068, 12116348.
20. Hansen S, Dahl R, Hoffmann HJ. Determination of blood leukocyte concentration with constant volume acquisition on a flow cytometer is comparable to individualized single platform testing with beads as internal reference standard. J Immunol Methods 2008, 338:58-62. 10.1016/j.jim.2008.07.010, 18680746.
21. Brown SG. Clinical features and severity grading of anaphylaxis. J Allergy Clin Immunol 2004, 114:371-376. 10.1016/j.jaci.2004.04.029, 15316518.
22. Erdmann SM, Sachs B, Kwiecien R, Moll-Slodowy S, Sauer I, Merk HF. The basophil activation test in wasp venom allergy: sensitivity, specificity and monitoring specific immunotherapy. Allergy 2004, 59:1102-1109. 10.1111/j.1398-9995.2004.00624.x, 15355470.
23. Ebo DG, Hagendorens MM, Schuerwegh AJ, Beirens LM, Bridts CH, De Clerck LS, Stevens WJ. Flow-assisted quantification of in vitro activated basophils in the diagnosis of wasp venom allergy and follow-up of wasp venom immunotherapy. Cytometry B Clin Cytom 2007, 72:196-203.
24. Eberlein-Konig B, Varga R, Mempel M, Darsow U, Behrendt H, Ring J. Comparison of basophil activation tests using CD63 or CD203c expression in patients with insect venom allergy. Allergy 2006, 61:1084-1085. 10.1111/j.1398-9995.2006.01122.x, 16918511.
25. Johansson SG, Nopp A, van Hage M, Olofsson N, Lundahl J, Wehlin L, Soderstrom L, Stiller V, Oman H. Passive IgE-sensitization by blood transfusion. Allergy 2005, 60:1192-1199. 10.1111/j.1398-9995.2005.00870.x, 16076307.
26. Boumiza R, Monneret G, Forissier MF, Savoye J, Gutowski MC, Powell WS, Bienvenu J. Marked improvement of the basophil activation test by detecting CD203c instead of CD63. Clin Exp Allergy 2003, 33:259-265. 10.1046/j.1365-2222.2003.01594.x, 12580920.
27. Ocmant A, Peignois Y, Mulier S, Hanssens L, Michils A, Schandene L. Flow cytometry for basophil activation markers: the measurement of CD203c up-regulation is as reliable as CD63 expression in the diagnosis of cat allergy. J Immunol Methods 2007, 320:40-48. 10.1016/j.jim.2006.12.002, 17275019.
28. Abuaf N, Rostane H, Rajoely B, Gaouar H, Autegarden JE, Leynadier F, Girot R. Comparison of two basophil activation markers CD63 and CD203c in the diagnosis of amoxicillin allergy. Clin Exp Allergy 2008, 38:921-928. 10.1111/j.1365-2222.2008.02960.x, 18331364.
29. Ducrest S, Meier F, Tschopp C, Pavlovic R, Dahinden CA. Flowcytometric analysis of basophil counts in human blood and inaccuracy of hematology analyzers. Allergy 2005, 60:1446-1450. 10.1111/j.1398-9995.2005.00910.x, 16197480.
30. Ebo DG, Hagendorens MM, Bridts CH, De Clerck LS, Stevens WJ. Hymenoptera venom allergy: taking the sting out of difficult cases. J Investig Allergol Clin Immunol 2007, 17:357-360.