Extending the transposable payload limit of Sleeping Beauty (SB) using the Herpes Simplex Virus (HSV)/SB amplicon-vector platform

Gene Therapy

Volumn 17, Issue 3, 2010, Pages 424-431

  De Silva, S ^a,b   Mastrangelo, M A ^b   Lotta, L T ^b   Burris, C A ^b   Federoff, H J ^c   Bowers, W J ^a,b  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

HSV 1 amplicon; Integration capacity; Sleeping Beauty

Indexed keywords

DNA; HERPESVIRUS VECTOR; SLEEPING BEAUTY TRANSPOSASE; TRANSPOSASE; UNCLASSIFIED DRUG;

AMPLICON; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; DNA TRANSPOSITION; EPISOME; GENE EXPRESSION; GENE TARGETING; HERPES SIMPLEX VIRUS 1; HOST CELL; HUMAN; HUMAN CELL; HUMAN GENOME; IN VIVO STUDY; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; REPORTER GENE; TRANSGENE; TRANSPOSON;

DNA TRANSPOSABLE ELEMENTS; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HELA CELLS; HERPESVIRUS 1, HUMAN; HUMANS; TRANSGENES; TRANSPOSASES; VIRUS INTEGRATION;

HUMAN HERPESVIRUS 1; SIMPLEXVIRUS;

EID: 77949424446     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2009.144     Document Type: Article

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