Binding of azole antibiotics to Staphylococcus aureus flavohemoglobin increases intracellular oxidative stress

Journal of Bacteriology

Volumn 192, Issue 6, 2010, Pages 1527-1533

  Nobre, Lígia S ^a   Todorovic, Smilja ^a   Tavares, Ana Filipa N ^a   Oldfield, Eric ^b   Hildebrandt, Peter ^c   Teixeira, Miguel ^a   Saraiva, Lígia M ^a  

^a INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CLOTRIMAZOLE; FLAVOHEMOGLOBIN; FLUCONAZOLE; HEMOGLOBIN; IMIDAZOLE DERIVATIVE; ITRACONAZOLE; KETOCONAZOLE; MICONAZOLE; REACTIVE OXYGEN METABOLITE; SULCONAZOLE; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CELL; BACTERIAL VIABILITY; CONTROLLED STUDY; DRUG MECHANISM; GENE DELETION; INTERNALIZATION; MACROPHAGE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PLASMID; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; WILD TYPE;

ANIMALS; ANTI-BACTERIAL AGENTS; AZOLES; BACTERIAL PROTEINS; HEMEPROTEINS; MACROPHAGES; MICE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; STAPHYLOCOCCUS AUREUS;

MURINAE; STAPHYLOCOCCUS AUREUS;

EID: 77949410758     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.01378-09     Document Type: Article

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