Effects of selective alpha 2-adrenoreceptor stimulation on capsaicin-evoked substance P release from primary cultured dorsal root ganglion neurons

Pharmazie

Volumn 65, Issue 3, 2010, Pages 202-205

  Gong, Huicui ^a   Liu, Qian ^b   Yang, Xiangdong ^c   Liu, Zhen ^a   Liu, Guixiang ^d   Li, Zhenzhong ^a  

^a SHANDONG UNIVERSITY   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

^c SHANDONG UNIVERSITY   (China)

^d BINZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; CAPSAICIN; CLONIDINE; MESSENGER RNA; SUBSTANCE P; VANILLOID RECEPTOR 1; YOHIMBINE;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CONTROLLED STUDY; EMBRYO; EMBRYO CELL; NEUROGENIC INFLAMMATION; NOCICEPTIVE RECEPTOR; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SECRETION; RADIOIMMUNOASSAY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSORY NERVE CELL; SPINAL GANGLION;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; CAPSAICIN; CELLS, CULTURED; CLONIDINE; GANGLIA, SPINAL; NEURONS; RADIOIMMUNOASSAY; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUBSTANCE P; TRPV CATION CHANNELS; YOHIMBINE;

EID: 77949387536     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2010.9697     Document Type: Article

References (20)

1. Banik RK, Sato J, Yajima H, Mizumura K (2001) Differences between the Lewis and Sprague-Dawley rats in chronic inflammation induced norepinephrine sensitivity of cutaneous C-fiber nociceptors. Neurosci Lett 299: 21-24.
2. Birder LA, Perl ER (1999) Expression of alpha2-adrenergic receptors in rat primary afferent neurones after peripheral nerve injury or inflammation. J Physiol 515: 533-542.
3. Dogrul A, Uzbay IT (2004) Topical clonidine antinociception. Pain 111: 385-391.
4. Gold MS, Dastmalchi S, Levine JD (1997) Alpha 2-adrenergic receptor subtypes in rat dorsal root and superior cervical ganglion neurons. Pain 69: 179-190.
5. Hingtgen CM, Waite KJ, Vasko MR (1995) Prostaglandins facilitate peptide release from rat sensory neurons by activating the adenosine 3′,5′-cyclic monophosphate transduction cascade. J Neurosci 15: 5411-5419.
6. Jänig W, Levine JD, Michaelis M (1996) Interactions of sympathetic and primary afferent neurons following nerve injury and tissue trauma. Prog Brain Res 113: 161-184.
7. Kingery WS, Guo TZ, Davies MF, Limbird L, Maze M (2000) The alpha(2A) adrenoceptor and the sympathetic postganglionic neuron contribute to the development of neuropathic heat hyperalgesia in mice. Pain 85: 345-358.
8. Lavand'homme PM, Ma W, De Kock M, Eisenach JC (2002) Perineural alpha (2A)-adrenoceptor inhibits spinal cord neuroplasticity and tactile allodynia after nerve injury. Anesthesiology 97: 972-980.
9. Lee Y, Lee CH, Oh U (2005) Painful channels in sensory neurons. Mol Cells 20: 315-324.
10. Ma W, Zhang Y, Bantel C, Eisenach JC (2005) Medium and large injured dorsal root ganglion cells increase TRPV-1, accompanied by increased alpha2C-adrenoceptor co-expression and functional inhibition by clonidine. Pain 113: 386-394.
11. Oh U, Hwang SW, Kim D (1996) Capsaicin activates a nonselective cation channel in cultured neonatal rat dorsal root ganglion neurons. J Neurosci 16: 1659-1667.
12. Pertovaara A (2006) Noradrenergic pain modulation. Prog Neurobiol 80: 53-83.
13. Ribeiro-da-Silva A, Hökfelt T (2000) Neuroanatomical localisation of substance P in the CNS and sensory neurons. Neuropeptides 34: 256-271.
14. Safieh-Garabedian B, Poole S, Haddad JJ, Massaad CA, Jabbur SJ, Saadé NE (2002) The role of the sympathetic efferents in endotoxin-induced localized inflammatory hyperalgesia and cytokine upregulation. Neuropharmacology 42: 864-872.
15. Shi TS, Winzer-Serhan U, Leslie F, Hokfelt T (2000) Distribution and regulation of alpha(2)-adrenoceptors in rat dorsal root ganglia. Pain 84: 319-330.
16. Tominaga M, Tominaga T (2005) Structure and function of TRPV1. Pflugers Arch 451: 143-150.
17. Trevisani M, Campi B, Gatti R, Andre E, Materazzi S, Nicoletti P, Gazzieri D, Geppetti P (2007) The influence of alpha(1)-adrenoreceptors on neuropeptide release from primary sensory neurons of the lower urinary tract. Eur Urol 52: 901-908.
18. Wei H, Jyvasjarvi E, Niissalo S, Hukkanen M, Waris E, Konttinen YT, Pertovaara A (2002) The influence of chemical sympathectomy on pain responsivity and alpha 2-adrenergic antinociception in neuropathic animals. Neuroscience 114: 655-668.
19. Winston J, Toma H, Shenoy M, Pasricha PJ (2001) Nerve growth factor regulates VR-1 mRNA levels in cultures of adult dorsal root ganglion neurons. Pain 89: 181-186.
20. Xing Y, Liu Z, Wang LH, Huang F, Wang HJ, Li ZZ (2006) Butyrate sensitizes the release of substance P and calcitonin gene-related peptide evoked by capsaicin from primary cultured rat dorsal root ganglion neurons. Neuroendocrinol Lett 27: 695-701.