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Volumn 86, Issue 1, 2010, Pages 131-140

The Rho protein exchange factor Vav3 regulates vascular smooth muscle cell proliferation and migration

Author keywords

Exchange factors; Rac1; Rho proteins; Signal transduction; Smooth muscle

Indexed keywords

2,3 DIHYDRO 2 OXO 3 (4,5,6,7 TETRAHYDRO 1H INDOL 2 YLMETHYLENE) 1H INDOLE 5 SULFONIC ACID DIMETHYLAMIDE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN TYROSINE KINASE INHIBITOR; RAC1 PROTEIN; RHO FACTOR; SMALL INTERFERING RNA; VAV PROTEIN;

EID: 77949356972     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvp387     Document Type: Article
Times cited : (28)

References (28)
  • 1
    • 33745684577 scopus 로고    scopus 로고
    • Regulation of Rho proteins by phosphorylation in the cardiovascular system
    • Loirand G, Guilluy C, Pacaud P. Regulation of Rho proteins by phosphorylation in the cardiovascular system. Trends Cardiovasc Med 2006;16:199-204.
    • (2006) Trends Cardiovasc Med , vol.16 , pp. 199-204
    • Loirand, G.1    Guilluy, C.2    Pacaud, P.3
  • 2
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: Biochemistry and biology
    • Jaffe AB, Hall A. Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol 2005;21:247-269.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 3
    • 0037213689 scopus 로고    scopus 로고
    • Rho GTPase-activating proteins in cell regulation
    • Moon SY, Zheng Y. Rho GTPase-activating proteins in cell regulation. Trends Cell Biol 2003;13:13-22.
    • (2003) Trends Cell Biol , vol.13 , pp. 13-22
    • Moon, S.Y.1    Zheng, Y.2
  • 4
    • 34249018367 scopus 로고    scopus 로고
    • GEFs and GAPs: Critical elements in the control of small G proteins
    • Bos JL, Rehmann H, Wittinghofer A. GEFs and GAPs: critical elements in the control of small G proteins. Cell 2007;129:865-877.
    • (2007) Cell , vol.129 , pp. 865-877
    • Bos, J.L.1    Rehmann, H.2    Wittinghofer, A.3
  • 5
    • 0942279704 scopus 로고    scopus 로고
    • Structural elements, mechanism, and evolutionary convergence of Rho protein-guanine nucleotide exchange factor complexes
    • Erickson JW, Cerione RA. Structural elements, mechanism, and evolutionary convergence of Rho protein-guanine nucleotide exchange factor complexes. Biochemistry 2004;43:837-842.
    • (2004) Biochemistry , vol.43 , pp. 837-842
    • Erickson, J.W.1    Cerione, R.A.2
  • 6
    • 13444252631 scopus 로고    scopus 로고
    • GEF means go: Turning on RHO GTPases with guanine nucleotide-exchange factors
    • Rossman KL, Der CJ, Sondek J. GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat Rev Mol Cell Biol 2005;6:167-180.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 167-180
    • Rossman, K.L.1    CJ, D.2    Sondek, J.3
  • 7
    • 34447318332 scopus 로고    scopus 로고
    • Increased PDZ-RhoGEF/RhoA/Rho kinase signaling in small mesenteric arteries of angiotensin II-induced hypertensive rats
    • Hilgers RH, Todd J Jr, Webb RC. Increased PDZ-RhoGEF/RhoA/Rho kinase signaling in small mesenteric arteries of angiotensin II-induced hypertensive rats. J Hypertens 2007;25:1687-1697.
    • (2007) J Hypertens , vol.25 , pp. 1687-1697
    • Hilgers, R.H.1    Todd Jr, J.2    Webb, R.C.3
  • 8
    • 33644836601 scopus 로고    scopus 로고
    • Angiotensin II up-regulates the leukemia-associated Rho guanine nucleotide exchange factor (RhoGEF), a regulator of G protein signaling domain-containing RhoGEF, in vascular smooth muscle cells
    • Ying Z, Jin L, Palmer T, Webb RC. Angiotensin II up-regulates the leukemia-associated Rho guanine nucleotide exchange factor (RhoGEF), a regulator of G protein signaling domain-containing RhoGEF, in vascular smooth muscle cells. Mol Pharmacol 2006;69: 932-940.
    • (2006) Mol Pharmacol , vol.69 , pp. 932-940
    • Ying, Z.1    Jin, L.2    Palmer, T.3    Webb, R.C.4
  • 9
    • 5444222639 scopus 로고    scopus 로고
    • Increased expression of mRNA for regulator of G protein signaling domain-containing Rho guanine nucleotide exchange factors in aorta from stroke-prone spontaneously hypertensive rats
    • Ying Z, Jin L, Dorrance AM, Webb RC. Increased expression of mRNA for regulator of G protein signaling domain-containing Rho guanine nucleotide exchange factors in aorta from stroke-prone spontaneously hypertensive rats. Am J Hypertens 2004;17: 981-985.
    • (2004) Am J Hypertens , vol.17 , pp. 981-985
    • Ying, Z.1    Jin, L.2    Dorrance, A.M.3    Webb, R.C.4
  • 10
    • 2342580708 scopus 로고    scopus 로고
    • RhoA activation in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats
    • Moriki N, Ito M, Seko T, Kureishi Y, Okamoto R, Nakakuki T et al. RhoA activation in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats. Hypertens Res 2004;27:263-270.
    • (2004) Hypertens Res , vol.27 , pp. 263-270
    • Moriki, N.1    Ito, M.2    Seko, T.3    Kureishi, Y.4    Okamoto, R.5    Nakakuki, T.6
  • 11
    • 24144470454 scopus 로고    scopus 로고
    • Signal-crosstalk between Rho/ROCK and c-Jun NH2-terminal kinase mediates migration of vascular smooth muscle cells stimulated by angiotensin II
    • Ohtsu H, Mifune M, Frank GD, Saito S, Inagami T, Kim-Mitsuyama S et al. Signal-crosstalk between Rho/ROCK and c-Jun NH2-terminal kinase mediates migration of vascular smooth muscle cells stimulated by angiotensin II. Arterioscler Thromb Vasc Biol 2005;25:1831-1836.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1831-1836
    • Ohtsu, H.1    Mifune, M.2    Frank, G.D.3    Saito, S.4    Inagami, T.5    Kim-Mitsuyama, S.6
  • 12
    • 13144266902 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma ligands inhibit Rho/Rho kinase pathway by inducing protein tyrosine phosphatase SHP-2
    • Wakino S, Hayashi K, Kanda T, Tatematsu S, Homma K, Yoshioka K et al. Peroxisome proliferator-activated receptor gamma ligands inhibit Rho/Rho kinase pathway by inducing protein tyrosine phosphatase SHP-2. Circ Res 2004;95:e45-e55.
    • (2004) Circ Res , vol.95
    • Wakino, S.1    Hayashi, K.2    Kanda, T.3    Tatematsu, S.4    Homma, K.5    Yoshioka, K.6
  • 13
    • 0033974061 scopus 로고    scopus 로고
    • Regulatory and signaling properties of the Vav family
    • Bustelo XR. Regulatory and signaling properties of the Vav family. Mol Cell Biol 2000;20:1461-1477.
    • (2000) Mol Cell Biol , vol.20 , pp. 1461-1477
    • Bustelo, X.R.1
  • 14
    • 38049017120 scopus 로고    scopus 로고
    • G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension
    • Wirth A, Benyo Z, Lukasova M, Leutgeb B, Wettschureck N, Gorbey S et al. G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension. Nat Med 2008;14:64-68.
    • (2008) Nat Med , vol.14 , pp. 64-68
    • Wirth, A.1    Benyo, Z.2    Lukasova, M.3    Leutgeb, B.4    Wettschureck, N.5    Gorbey, S.6
  • 16
    • 35648995843 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in human varicose veins: Involvement of matrix gla protein in extracellular matrix remodeling
    • Cario-Toumaniantz C, Boularan C, Schurgers LJ, Heymann MF, Le Cunff M, Leger J et al. Identification of differentially expressed genes in human varicose veins: involvement of matrix gla protein in extracellular matrix remodeling. J Vasc Res 2007;44: 444-459.
    • (2007) J Vasc Res , vol.44 , pp. 444-459
    • Cario-Toumaniantz, C.1    Boularan, C.2    Schurgers, L.J.3    Heymann, M.F.4    Le Cunff, M.5    Leger, J.6
  • 17
    • 17644425743 scopus 로고    scopus 로고
    • Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76
    • Charvet C, Canonigo AJ, Billadeau DD, Altman A. Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76. J Biol Chem 2005;280:15289-15299.
    • (2005) J Biol Chem , vol.280 , pp. 15289-15299
    • Charvet, C.1    Canonigo, A.J.2    Billadeau, D.D.3    Altman, A.4
  • 18
    • 33749647713 scopus 로고    scopus 로고
    • Hyaluronan induces vascular smooth muscle cell migration through RHAMM-mediated PI3K-dependent Rac activation
    • Goueffic Y, Guilluy C, Guerin P, Patra P, Pacaud P, Loirand G. Hyaluronan induces vascular smooth muscle cell migration through RHAMM-mediated PI3K-dependent Rac activation. Cardiovasc Res 2006;72:339-348.
    • (2006) Cardiovasc Res , vol.72 , pp. 339-348
    • Goueffic, Y.1    Guilluy, C.2    Guerin, P.3    Patra, P.4    Pacaud, P.5    Loirand, G.6
  • 19
    • 0034461581 scopus 로고    scopus 로고
    • Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation
    • Zeng L, Sachdev P, Yan L, Chan JL, Trenkle T, McClelland M et al. Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation. Mol Cell Biol 2000;20:9212-9224.
    • (2000) Mol Cell Biol , vol.20 , pp. 9212-9224
    • Zeng, L.1    Sachdev, P.2    Yan, L.3    Chan, J.L.4    Trenkle, T.5    McClelland, M.6
  • 20
    • 54149099613 scopus 로고    scopus 로고
    • Rho GTPase, Rac1, regulates Skp2 levels, vascular smooth muscle cell proliferation, and intima formation in vitro and in vivo
    • Bond M, Wu YJ, Sala-Newby GB, Newby AC. Rho GTPase, Rac1, regulates Skp2 levels, vascular smooth muscle cell proliferation, and intima formation in vitro and in vivo. Cardiovasc Res 2008;80:290-298.
    • (2008) Cardiovasc Res , vol.80 , pp. 290-298
    • Bond, M.1    Wu, Y.J.2    Sala-Newby, G.B.3    Newby, A.C.4
  • 21
    • 0033604638 scopus 로고    scopus 로고
    • Signaling to Rho GTPases
    • Kjoller L, Hall A. Signaling to Rho GTPases. Exp Cell Res 1999;253:166-179.
    • (1999) Exp Cell Res , vol.253 , pp. 166-179
    • Kjoller, L.1    Hall, A.2
  • 22
    • 0033594123 scopus 로고    scopus 로고
    • Rho GTPases control polarity, protrusion, and adhesion during cell movement
    • Nobes CD, Hall A. Rho GTPases control polarity, protrusion, and adhesion during cell movement. J Cell Biol 1999;144:1235-1244.
    • (1999) J Cell Biol , vol.144 , pp. 1235-1244
    • Nobes, C.D.1    Hall, A.2
  • 23
    • 0035093056 scopus 로고    scopus 로고
    • Cytoskeletal effects of rho-like small guanine nucleotide-binding proteins in the vascular system
    • van Nieuw Amerongen GP, van Hinsbergh VW. Cytoskeletal effects of rho-like small guanine nucleotide-binding proteins in the vascular system. Arterioscler Thromb Vasc Biol 2001;21:300-311.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 300-311
    • van Nieuw Amerongen, G.P.1    van Hinsbergh, V.W.2
  • 24
    • 33645285957 scopus 로고    scopus 로고
    • Regulation of NADPH oxidases: The role of Rac proteins
    • Hordijk PL. Regulation of NADPH oxidases: the role of Rac proteins. Circ Res 2006;98:453-462.
    • (2006) Circ Res , vol.98 , pp. 453-462
    • Hordijk, P.L.1
  • 25
    • 0031026132 scopus 로고    scopus 로고
    • Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways
    • Westwick JK, Lambert QT, Clark GJ, Symons M, Van Aelst L, Pestell RG et al. Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways. Mol Cell Biol 1997;17:1324-1335.
    • (1997) Mol Cell Biol , vol.17 , pp. 1324-1335
    • Westwick, J.K.1    Lambert, Q.T.2    Clark, G.J.3    Symons, M.4    Van Aelst, L.5    Pestell, R.G.6
  • 26
    • 0032696592 scopus 로고    scopus 로고
    • Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins
    • Movilla N, Bustelo XR. Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins. Mol Cell Biol 1999;19:7870-7885.
    • (1999) Mol Cell Biol , vol.19 , pp. 7870-7885
    • Movilla, N.1    Bustelo, X.R.2
  • 27
    • 33845608726 scopus 로고    scopus 로고
    • Regulation of cell-matrix adhesion dynamics and Rac-1 by integrin linked kinase
    • Boulter E, Grall D, Cagnol S, Van Obberghen-Schilling E. Regulation of cell-matrix adhesion dynamics and Rac-1 by integrin linked kinase. FASEB J 2006;20:1489-1491.
    • (2006) FASEB J , vol.20 , pp. 1489-1491
    • Boulter, E.1    Grall, D.2    Cagnol, S.3    Van Obberghen-Schilling, E.4
  • 28
    • 0029278739 scopus 로고
    • PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase
    • Hawkins PT, Eguinoa A, Qiu RG, Stokoe D, Cooke FT, Walters R et al. PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase. Curr Biol 1995;5:393-403.
    • (1995) Curr Biol , vol.5 , pp. 393-403
    • Hawkins, P.T.1    Eguinoa, A.2    Qiu, R.G.3    Stokoe, D.4    Cooke, F.T.5    Walters, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.