The effects of neurokinin B upon gonadotrophin release in male rodents

Journal of Neuroendocrinology

Volumn 22, Issue 3, 2010, Pages 181-187

  Corander, M P ^a   Challis, B G ^a   Thompson, E L ^b   Jovanovic, Z ^a   Loraine Tung, Y C ^a   Rimmington, D ^a   Huhtaniemi, I T ^c   Murphy, K G ^b   Topaloglu, A K ^d   Yeo, G S H ^a   O'Rahilly, S ^a   Dhillo, W S ^b   Semple, R K ^a   Coll, A P ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d CUKUROVA UNIVERSITY   (Turkey)

Author keywords

Gonadotrophin; Kisspeptin; NKB; Rodent

Indexed keywords

G PROTEIN COUPLED RECEPTOR 54; GONADORELIN; KISSPEPTIN; LUTEINIZING HORMONE; NEUROKININ B; TACHYKININ; TACHYKININ RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EX VIVO STUDY; GENE EXPRESSION; GONADORELIN RELEASE; HORMONE DETERMINATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; REPRODUCTION;

ANIMALS; ARCUATE NUCLEUS; FASTING; GONADOTROPIN-RELEASING HORMONE; LUTEINIZING HORMONE; MALE; MICE; MICE, INBRED C57BL; NEUROKININ B; PROTEIN PRECURSORS; PROTEINS; RATS; RATS, WISTAR; RECEPTORS, TACHYKININ; TACHYKININS;

EID: 77949303387     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/j.1365-2826.2009.01951.x     Document Type: Article

References (33)

1. Pennefather JN, Lecci A, Candenas ML, Patak E, Pinto FM, Maggi CA. Tachykinins and tachykinin receptors: a growing family. Life Sci 2004, 74:1445-1463.
2. Severini C, Improta G, Falconieri-Erspamer G, Salvadori S, Erspamer V. The tachykinin peptide family. Pharmacol Rev 2002, 54:285-322.
3. Arisawa M, De Palatis L, Ho R, Snyder GD, Yu WH, Pan G, McCann SM. Stimulatory role of substance P on gonadotropin release in ovariectomized rats. Neuroendocrinology 1990, 51:523-529.
4. Kalra PS, Sahu A, Bonavera JJ, Kalra SP. Diverse effects of tachykinins on luteinizing hormone release in male rats: mechanism of action. Endocrinology 1992, 131:1195-1201.
5. Krajewski SJ, Anderson MJ, Iles-Shih L, Chen KJ, Urbanski HF, Rance NE. Morphologic evidence that neurokinin B modulates gonadotropin-releasing hormone secretion via neurokinin 3 receptors in the rat median eminence. J Comp Neurol 2005, 489:372-386.
6. Sandoval-Guzman T, Rance NE. Central injection of senktide, an NK3 receptor agonist, or neuropeptide Y inhibits LH secretion and induces different patterns of Fos expression in the rat hypothalamus. Brain Res 2004, 1026:307-312.
7. McManus CJ, Valent M, Connors JM, Lehman MN, Goodman R. A neurokinin - B Agonist Stimulates LT Secretion in Follicular, but not Luteal, Phase Ewes 2005, Abstract Viewer/Itinerary Planner, Washington, DC, Society for Neuroscience
8. Guran T, Tolhurst G, Bereket A, Rocha N, Porter K, Turan S, Gribble FM, Kotan LD, Akcay T, Atay Z, Canan H, Serin A, O'Rahilly S, Reimann F, Semple RK, Topaloglu AK. Hypogonadotropic hypogonadism due to a novel missense mutation in the first extracellular loop of the neurokinin B receptor. J Clin Endocrinol Metab 2009, 94:3633-3639.
9. Topaloglu AK, Reimann F, Guclu M, Yalin AS, Kotan LD, Porter KM, Serin A, Mungan NO, Cook JR, Ozbek MN, Imamoglu S, Akalin NS, Yuksel B, O'Rahilly S, Semple RK. TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for neurokinin B in the central control of reproduction. Nat Genet 2009, 41:354-358.
10. Dhillo WS. Kisspeptin: a novel regulator of reproductive function. J Neuroendocrinol 2008, 20:963-970.
11. Seminara SB, Crowley WF. Kisspeptin and GPR54: discovery of a novel pathway in reproduction. J Neuroendocrinol 2008, 20:727-731.
12. Goodman RL, Lehman MN, Smith JT, Coolen LM, De Oliveira CV, Jafarzadehshirazi MR, Pereira A, Iqbal J, Caraty A, Ciofi P, Clarke IJ. Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B. Endocrinology 2007, 148:5752-5760.
13. Rometo AM, Krajewski SJ, Voytko ML, Rance NE. Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular nucleus of postmenopausal women and ovariectomized monkeys. J Clin Endocrinol Metab 2007, 92:2744-2750.
14. Kauffman AS, Navarro VM, Kim J, Clifton D, Steiner RA. Sex differences in the regulation of Kiss1/NKB neurons in juvenile mice: implications for the timing of puberty. Am J Physiol Endocrinol Metab 2009, 297:E1212-E1221.
15. Thompson EL, Patterson M, Murphy KG, Smith KL, Dhillo WS, Todd JF, Ghatei MA, Bloom SR. Central and peripheral administration of kisspeptin-10 stimulates the hypothalamic-pituitary-gonadal axis. J Neuroendocrinol 2004, 16:850-858.
16. Haavisto AM, Pettersson K, Bergendahl M, Perheentupa A, Roser JF, Huhtaniemi I. A supersensitive immunofluorometric assay for rat luteinizing hormone. Endocrinology 1993, 132:1687-1691.
17. Prieur X, Tung YC, Griffin JL, Farooqi IS, O'Rahilly S, Coll AP. Leptin regulates peripheral lipid metabolism primarily through central effects on food intake. Endocrinology 2008, 149:5432-5439.
18. Stanley SA, Small CJ, Kim MS, Heath MM, Seal LJ, Russell SH, Ghatei MA, Bloom SR. Agouti related peptide (Agrp) stimulates the hypothalamo pituitary gonadal axis in vivo & in vitro in male rats. Endocrinology 1999, 140:5459-5462.
19. Beak SA, Heath MM, Small CJ, Morgan DG, Ghatei MA, Taylor AD, Buckingham JC, Bloom SR, Smith DM. Glucagon-like peptide-1 stimulates luteinizing hormone-releasing hormone secretion in a rodent hypothalamic neuronal cell line. J Clin Invest 1998, 101:1334-1341.
20. Tung YC, Ma M, Piper S, Coll A, O'Rahilly S, Yeo GS. Novel leptin-regulated genes revealed by transcriptional profiling of the hypothalamic paraventricular nucleus. J Neurosci 2008, 28:12419-12426.
21. Sahu A, Kalra SP. Effects of tachykinins on luteinizing hormone release in female rats: potent inhibitory action of neuropeptide K. Endocrinology 1992, 130:1571-1577.
22. Pillon D, Caraty A, Fabre-Nys C, Bruneau G. Short-term effect of oestradiol on neurokinin B mRNA expression in the infundibular nucleus of ewes. J Neuroendocrinol 2003, 15:749-753.
23. Gottsch ML, Cunningham MJ, Smith JT, Popa SM, Acohido BV, Crowley WF, Seminara S, Clifton DK, Steiner RA. A role for kisspeptins in the regulation of gonadotropin secretion in the mouse. Endocrinology 2004, 145:4073-4077.
24. Matsui H, Takatsu Y, Kumano S, Matsumoto H, Ohtaki T. Peripheral administration of metastin induces marked gonadotropin release and ovulation in the rat. Biochem Biophys Res Commun 2004, 320:383-388.
25. Smith JT, Acohido BV, Clifton DK, Steiner RA. KiSS-1 neurones are direct targets for leptin in the ob/ob mouse. J Neuroendocrinol 2006, 18:298-303.
26. Nagatani S, Guthikonda P, Thompson RC, Tsukamura H, Maeda KI, Foster DL. Evidence for GnRH regulation by leptin: leptin administration prevents reduced pulsatile LH secretion during fasting. Neuroendocrinology 1998, 67:370-376.
27. Danzer SC, Price RO, McMullen NT, Rance NE. Sex steroid modulation of neurokinin B gene expression in the arcuate nucleus of adult male rats. Brain Res Mol Brain Res 1999, 2:200-204.
28. Forbes S, Li XF, Kinsey-Jones J, O'Byrne K. Effects of ghrelin on Kisspeptin mRNA expression in the hypothalamic medial preoptic area and pulsatile luteinising hormone secretion in the female rat. Neurosci Lett 2009, 460:143-147.
29. Castellano JM, Navarro VM, Fernandez-Fernandez R, Nogueiras R, Tovar S, Roa J, Vazquez MJ, Vigo E, Casanueva FF, Aguilar E, Pinilla L, Dieguez C, Tena-Sempere M. Changes in hypothalamic KiSS-1 system and restoration of pubertal activation of the reproductive axis by kisspeptin in undernutrition. Endocrinology 2005, 146:3917-3925.
30. Luque RM, Kineman RD, Tena-Sempere M. Regulation of hypothalamic expression of KiSS-1 and GPR54 genes by metabolic factors: analyses using mouse models and a cell line. Endocrinology 2007, 148:4601-4611.
31. Donato J, Silva RJ, Sita LV, Lee S, Lee C, Lacchini S, Bittencourt JC, Franci CR, Canteras NS, Elias CF. The ventral premammillary nucleus links fasting-induced changes in leptin levels and coordinated luteinizing hormone secretion. J Neurosci 2009, 29:5240-5250.
32. Leshan RL, Louis GW, Jo YH, Rhodes CJ, Munzberg H, Myers MG. Direct innervation of GnRH neurons by metabolic- and sexual odorant-sensing leptin receptor neurons in the hypothalamic ventral premammillary nucleus. J Neurosci 2009, 29:3138-3147.
33. Kung TT, Crawley Y, Jones H, Luo B, Gilchrest H, Greenfeder S, Anthes JC, Lira S, Wiekowski M, Cook DN, Hey JA, Egan RW, Chapman RW. Tachykinin NK3-receptor deficiency does not inhibit pulmonary eosinophilia in allergic mice. Pharmacol Res 2004, 50:611-615.