Disease-modifying Effects of Glucosamine on Interleukin-1β-treated Chondrosarcoma Cells (SW1353) Under Normoxic and Hypoxic Conditions

Journal of Experimental and Clinical Medicine

Volumn 2, Issue 1, 2010, Pages 17-28

  Chen, Ta Liang ^a   Sheu, Ming Thau ^a   Liang, Yu Chih ^a   Lin, Yu Ju ^a   Hsieh, Ming Shium ^a   Chen, Chien Ho ^a  

^a TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

chondrosarcoma cells; glucosamine; glucose transporter 1; hypoxia induced factor 1 ; interleukin 1 ; matrix metalloproteinases; osteoarthritis

Indexed keywords

GLUCOSAMINE; GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 1BETA; MATRIX METALLOPROTEINASE; MESSENGER RNA; OXYGEN;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CARTILAGE; CELL HYPOXIA; CELL LEVEL; CHONDROSARCOMA; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG PROTEIN BINDING; HUMAN; HUMAN CELL; OXYGEN CONCENTRATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARCOMA CELL; UPREGULATION; WESTERN BLOTTING;

EID: 77949279422     PISSN: 18783317     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1878-3317(10)60004-6     Document Type: Article

References (43)

1. Coimbra I.B., Jimenez S.A., Hawkins D.F., Piera-Velazquez S., and Stokes D.G. Hypoxia inducible factor-1 alpha expression in human normal and osteoarthritic chondrocytes. Osteoarthr Cartil 12 (2004) 336-345
2. Shapiro I.M., Tokuoka T., and Silverton S.F. Energy metabolism in cartilage. In: Hall B.K., and Newman S. (Eds). Cartilage: Molecular Aspects (1991), CRC Press, Boston 97-130
3. 2 and blood flow in the rabbit knee joint due to stimulation of the posterior articular nerve. J Physiol 449 (1992) 607-617
4. Lewis J.S., Lee J.A., Underwood J.C., Harris A.L., and Lewis C.E. Macrophage responses to hypoxia: relevance to disease mechanisms. J Leukoc Biol 66 (1999) 889-900
5. Schipani E., Ryan H.E., Didrickson S., Kobayashi T., Knight M., and Johnson R.S. Hypoxia in cartilage: HIF-1a is essential for chondrocyte growth arrest and survival. Genes Dev 15 (2001) 2865-2876
6. Wang G.L., and Semenza G.L. General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci USA 9 (1993) 4304-4308
7. 2 tension. Proc Natl Acad Sci USA 92 (1995) 5510-5514
8. Ysart G.E., and Mason R.M. Responses of articular cartilage explant cultures to different oxygen tensions. Biochim Biophys Acta 1221 (1994) 15-20
9. Grimshaw M.J., and Mason R.M. Bovine articular chondrocyte function in vitro depends upon oxygen tension. Osteoarthr Cartil 8 (2000) 386-392
10. Grimshaw M.J., and Mason R.M. Modulation of bovine articular chondrocyte gene expression in vitro by oxygen tension. Osteoarthr Cartil 9 (2001) 357-364
11. Murphy C.L., and Sambanis A. Effect of oxygen tension on chondrocyte extracellular matrix accumulation. Connect Tissue Res 42 (2001) 87-96
12. Cernanec J., Guilak F., Weinberg J.B., Pisetsky D.S., and Fermor B. Influence of hypoxia and reoxygenation on cytokine-induced production of proinflammatory mediators in articular cartilage. Arthritis Rheum 46 (2002) 968-975
13. Martin G., Andriamanalijaona R., Grässel S., Dreier R., Mathy-Hartert M., Bogdanowicz P., Boumédiene K., et al. Effect of hypoxia and reoxygenation on gene expression and response to interleukin-1 in cultured articular chondrocytes. Arthritis Rheum 50 (2004) 3549-3560
14. Abramson S.B., and Amin A. Blocking the effects of IL-1 in rheumatoid arthritis protects bone and cartilage. Rheumatology 41 (2002) 972-980
15. McAlindon T. Glucosamine for osteoarthritis: dawn of a new era?. Lancet 357 (2001) 247-248
16. Reginster J.Y., Deroisy R., Rovati L.C., Lee R.L., Lejeune E., Bruyere O., Giacovelli G., et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial. Lancet 357 (2001) 251-256
17. Gouze J.N., Bordji K., Gulberti S., Terlain B., Netter P., Magdalou J., Fournel-Gigleux S., et al. Interleukin-1β down-regulates the expression of glucuronosyltransferase I, a key enzyme priming glycosaminoglycan biosynthesis: influence of glucosamine on interleukin-1β-mediated effects in rat chondrocytes. Arthritis Rheum 44 (2001) 351-360
18. Gouze J.N., Bianchi A., Bécuwe P., Dauça M., Netter P., Magdalou J., Terlain B., et al. Glucosamine modulates IL-1-induced activation of rat chondrocytes at a receptor level, and by inhibiting the NF-?B pathway. FEBS Lett 510 (2002) 166-170
19. Largo R., Alvarez-Soria M.A., Díez-Ortego I., Calvo E., Sánchez-Pernaute O., Egido J., and Herrero-Beaumont G. Glucosamine inhibits IL-1β-induced NF-?B activation in human osteoarthritic chondrocytes. Osteoarthr Cartil 11 (2003) 290-298
20. Dodge G.R., and Jimenez S.A. Glucosamine sulfate modulates the levels of aggrecan and matrix metalloproteinase-3 synthesized by cultured human osteoarthritis articular chondrocytes. Osteoarthr Cartil 11 (2003) 424-432
21. 2 in articular cartilage explants. Osteoarthr Cartil 13 (2005) 387-394
22. Ren X., Dorrington K.L., Maxwell P.H., and Robbins P.A. Effects of desferrioxamine on serum erythropoietin and ventilatory sensitivity to hypoxia in humans. J Appl Physiol 89 (2000) 680-686
23. Chomczynski P., and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162 (1987) 156-159
24. 2, nitric oxide and metalloproteases by chondrocytes and synoviocytes in osteoarthritis. Clin Exp Rheumatol 22 (2004) 293-299
25. de Mattei M., Pellati A., Pasello M., de Terlizzi F., Massari L., Gemmati D., and Caruso A. High doses of glucosamine-HCl have detrimental effects on bovine articular cartilage explants cultured in vitro. Osteoarthr Cartil 10 (2002) 816-825
26. Laverty S., Sandy J.D., Celeste C., Vachon P., Marier J.F., and Plaas A.H. Synovial fluid levels and serum pharmacokinetics in a large animal model following treatment with oral glucosamine at clinically relevant doses. Arthritis Rheum 52 (2005) 181-191
27. Lefebvre V., Peeters-Joris C., and Vaes G. Modulation by interleukin 1 and tumor necrosis factor alpha of production of collagenase, tissue inhibitor of metalloproteinases and collagen types in differentiated and dedifferentiated articular chondrocytes. Biochim Biophys Acta 1052 (1990) 366-378
28. Goodstone N.J., and Hardingham T.E. Tumour necrosis factor alpha stimulates nitric oxide production more potently than interleukin-1beta in porcine articular chondrocytes. Rheumatology (Oxford) 41 (2002) 883-891
29. Gouze J.N., Gouze E., Popp M.P., Bush M.L., Dacanay E.A., Kay J.D., Levings P.P., et al. Exogenous glucosamine globally protects chondrocytes from the arthritogenic effects of IL-1β. Arthritis Res Ther 8 (2006) R173
30. Silver I.A. Measurement of pH and ionic composition of pericellular sites. Philos Trans R Soc Lond B Biol Sci 271 (1975) 261-272
31. Lehninger A.L., Cox M.M., and Nelson D.L. Principles of Biochemistry. 2nd ed. (1993), Worth Publishers, New York
32. Stryer L. Biochemistry. 4th ed. (1995), W.H. Freeman, New York
33. Hernvann A., Jaffray P., Hilliquin P., Cazalet C., Menkes C.J., and Ekindjian O.G. Interleukin-1-mediated glucose uptake by chondrocytes: inhibition by cortisol. Osteoarthr Cartil 4 (1996) 139-142
34. Shikhman A.R., Brinson D.C., Valbracht J., and Lotz M.K. Cytokine regulation of facilitated glucose transport in human articular chondrocytes. J Immunol 167 (2001) 7001-7008
35. Pfander D., Cramer T., and Swoboda B. Hypoxia and HIF-1alpha in osteoarthritis. Int Orthop 29 (2005) 6-9
36. Otte P. Basic cell metabolism of articular cartilage. Manometric studies. Z Rheumatol 50 (1991) 304-312
37. Lee R.B., and Urban J.P. Evidence for a negative Pasteur effect in articular cartilage. Biochem J 321 (1997) 95-102
38. Kim J.J., and Conrad H.E. Kinetics of mucopolysaccharide and glycoprotein synthesis by chick embryo chondrocytes. Effect of D-glucose concentration in the culture medium. J Biol Chem 251 (1976) 6210-6217
39. Sweeney C., Mackintosh D., and Mason R.M. UDP-sugar metabolism in Swarm rat chondrosarcoma chondrocytes. Biochem J 290 (1993) 563-570
40. Mobasheri A., Vannucci S.J., Bondy C.A., Carter S.D., Innes J.F., Arteaga M.F., Trujillo E., et al. Glucose transport and metabolism in chondrocytes: a key to understanding chondrogenesis, skeletal development and cartilage degradation in osteoarthritis. Histol Histopathol 17 (2002) 1239-1267
41. Mason R.M., Kimura J.H., and Hascall V.C. Biosynthesis of hyaluronic acid in cultures of chondrocytes from the Swarm rat chondrosarcoma. J Biol Chem 257 (1982) 2236-2245
42. Rauchman M.I., Wasserman J.C., Cohen D.M., Perkins D.L., Hebert S.C., Milford E., and Gullans S.R. Expression of GLUT-2 cDNA in human B lymphocytes: analysis of glucose transport using flow cytometry. Biochim Biophys Acta 1111 (1992) 231-238
43. Cloherty E.K., Sultzman L.A., Zottola R.J., and Carruthers A. Net sugar transport is a multistep process. Evidence for cytosolic sugar binding sites in erythrocytes. Biochemistry 34 (1995) 15395-15406