Enhancement of glucagon secretion in mouse and human pancreatic alpha cells by protein kinase C (PKC) involves intracellular trafficking of PKCα and PKCδ

Diabetologia

Volumn 53, Issue 4, 2010, Pages 717-729

  De Marinis, Y Z ^a   Zhang, E ^a   Amisten, S ^b   Taneera, J ^a   Renstrom E ^a   Rorsman, P ^b   Eliasson, L ^a  

^a LUND UNIVERSITY   (Sweden)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

BIM; Ca2+; Exocytosis; Glucagon; Pancreatic alpha cell; PKC; PKC ; PKC ; PMA; Translocation

Indexed keywords

BISINDOLYLMALEIMIDE; CALCIUM CHANNEL; GLUCAGON; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C ALPHA; PROTEIN KINASE C DELTA; TISSUE CULTURE MEDIUM;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL MIGRATION; CONFOCAL MICROSCOPY; ENZYME ACTIVATION; EXOCYTOSIS; GENE EXPRESSION; GLUCAGON RELEASE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOUSE; NONHUMAN; PANCREAS ISLET ALPHA CELL; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; REAL TIME POLYMERASE CHAIN REACTION;

ADULT; AGED; ANIMALS; EXOCYTOSIS; GLUCAGON; GLUCAGON-SECRETING CELLS; HUMANS; MICE; MIDDLE AGED; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; PROTEIN KINASE C-DELTA; PROTEIN TRANSPORT; TETRADECANOYLPHORBOL ACETATE;

EID: 77949268993     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-009-1635-x     Document Type: Article

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