Angiotensin-converting enzyme gene polymorphism is associated with type 2 diabetes: A meta-analysis

Molecular Biology Reports

Volumn 37, Issue 1, 2010, Pages 67-73

  Zhou, Jian Bo ^a   Yang, Jin Kui ^a   Lu, Jing Kai ^a   An, Yan Hua ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

ACE polymorphism; Diabetes mellitus; Ethnic variation

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ARTICLE; ASIAN; CAUCASIAN; CELL HETEROGENEITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DNA POLYMORPHISM; EGGERTHELLA; ETHNIC DIFFERENCE; ETHNICITY; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; RISK ASSESSMENT; TURKEY (REPUBLIC);

CASE-CONTROL STUDIES; CONFIDENCE INTERVALS; DIABETES MELLITUS, TYPE 2; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INDEL MUTATION; ODDS RATIO; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, SINGLE NUCLEOTIDE; PUBLICATION BIAS;

EID: 77949267137     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-009-9648-6     Document Type: Article

References (55)

1. EG Erdös 1990 Angiotensin I converting enzyme and the changes in our concepts through the years. Lewis K. Dahl memorial lecture Hypertension 16 363 370 2170273
2. B Rigat C Hubert F Alhenc-Gelas F Cambien P Corvol F Soubrier 1990 An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels J Clin Invest 86 1343 1346 10.1172/JCI114844 10.1172/JCI114844 1:CAS:528:DyaK3cXmt1Gmt7s%3D 1976655
3. AH Danser MA Schalekamp WA Bax AM van den Brink PR Saxena GA Riegger H Schunkert 1995 Angiotensin-converting enzyme in the human heart: effect of the deletion/insertion polymorphism Circulation 92 1387 1388 1:CAS:528: DyaK2MXot1yitrw%3D 7664416
4. XH Huang V Rantalaiho O Wirta, et al. 1998 Relationship of the angiotensin-converting enzyme gene polymorphism to glucose intolerance, insulin resistance, and hypertension in NIDDM Hum Genet 102 372 378 10.1007/ s004390050707 10.1007/s004390050707 1:CAS:528:DyaK1cXhsFOgsrY%3D 9544854 (Pubitemid 28185230)
5. JW Stephens SS Dhamrait JA Cooper, et al. 2005 The D allele of the ACE I/D common gene variant is associated with Type 2 diabetes mellitus in Caucasian subjects Mol Genet Metab 84 83 89 10.1016/j.ymgme.2004.09.002 10.1016/j.ymgme.2004.09.002 1:CAS:528:DC%2BD2MXis1WjtA%3D%3D 15639198 (Pubitemid 40082608)
6. DJ Freeman J Norrie MJ Caslake, et al. 2002 West of Scotland Coronary Prevention Study. C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study Diabetes 51 1596 1600 10.2337/diabetes.51.5.1596 10.2337/diabetes.51.5.1596 1:CAS:528:DC%2BD38XjtlGmur8%3D 11978661
7. H Abuissa PG Jones SP Marso JH O'Keefe Jr 2005 Angiotensin-converting enzyme inhibitors or angiotensin receptor blockers for prevention of type 2 diabetes: a meta-analysis of randomized clinical trials J Am Coll Cardiol 46 821 826 10.1016/j.jacc.2005.05.051 10.1016/j.jacc.2005.05.051 1:CAS:528: DC%2BD2MXpslygs7c%3D 16139131 (Pubitemid 41224805)
8. M Egger SG Davey M Schneider C Minder 1997 Bias in meta-analysis detected by a simple, graphical test BMJ 315 629 634 1:STN:280:DyaK2svls1KjtA%3D%3D 9310563
9. SG Davey M Egger 1997 Meta-analyses of randomised controlled trials Lancet 350 1182
10. R DerSimonian N Laird 1986 Meta-analysis in clinical trials Control Clin Trials 7 177 188 10.1016/0197-2456(86)90046-2 10.1016/0197-2456(86)90046-2 1:STN:280:DyaL2s7gsVamtA%3D%3D 3802833 (Pubitemid 17189972)
11. J Lau EM Antman J Jimenez-Silva B Kupelnick F Mosteller TC Chalmers 1992 Cumulative meta-analysis of therapeutic trials for myocardial infarction N Engl J Med 327 248 254 1:STN:280:DyaK38zhtVCqsg%3D%3D 1614465
12. J Ioannidis J Lau 2001 Evolution of treatment effects over time: empirical insight from recursive cumulative meta analyses Proc Natl Acad Sci USA 98 831 836 10.1073/pnas.021529998 10.1073/pnas.021529998 1:CAS:528: DC%2BD3MXht1Snu74%3D 11158556 (Pubitemid 32121147)
13. CB Begg M Mazumdar 1994 Operating characteristics of a rank correlation test for publication bias Biometrics 50 1088 1101 10.2307/2533446 10.2307/2533446 1:STN:280:DyaK2Mzgs1GrtQ%3D%3D 7786990
14. E Zintzaras GM Hadjigeorgiou 2004 Association of paraoxonase 1 gene polymorphisms with risk of Parkinson's disease: a meta-analysis J Hum Genet 49 474 481 10.1007/s10038-004-0176-x 10.1007/s10038-004-0176-x 15368102 (Pubitemid 39314366)
15. DK Nagi MW Mansfield MH Stickland PJ Grant 1995 Angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism, and diabetic retinopathy in subjects with IDDM and NIDDM Diabet Med 12 997 1001 10.1111/j.1464-5491.1995. tb00412.x 1:STN:280:DyaK287ksFyitw%3D%3D 8582133
16. S Mizuiri H Hemmi A Inoue, et al. 1995 Angiotensin-converting enzyme polymorphism and development of diabetic nephropathy in non-insulin-dependent diabetes mellitus Nephron 70 455 459 10.1159/000188645 10.1159/000188645 1:CAS:528:DyaK2MXnsVeqtbc%3D 7477652
17. Y Doi H Yoshizumi M Yoshinari, et al. 1996 Association between a polymorphism in the angiotensin-converting enzyme gene and microvascular complications in Japanese patients with NIDDM Diabetologia 39 97 102 1:CAS:528:DyaK28Xhtlymsrk%3D 8720609
18. C Gutiérrez J Vendrell R Pastor, et al. 1997 Angiotensin I-converting enzyme and angiotensinogen gene polymorphisms in non-insulin-dependent diabetes mellitus. Lack of relationship with diabetic nephropathy and retinopathy in a Caucasian Mediterranean population Metabolism 46 976 980 10.1016/S0026-0495(97)90090-1 10.1016/S0026-0495(97)90090-1 9258285 (Pubitemid 27339927)
19. LM Chuang KC Chiu FT Chiang, et al. 1997 Insertion/deletion polymorphism of the angiotensin I-converting enzyme gene in patients with hypertension, non-insulin-dependent diabetes mellitus, and coronary heart disease in Taiwan Metabolism 46 1211 1214 10.1016/S0026-0495(97)90219-5 10.1016/S0026-0495(97) 90219-5 1:CAS:528:DyaK2sXmslOgtLc%3D 9322809 (Pubitemid 27418514)
20. S Wu K Xiang Q Weng, et al. 1998 Relationship between angiotensin I converting enzyme gene polymorphism and diabetic nephropathy Chin Med J (Engl) 111 478 479 1:CAS:528:DyaK1cXjvVCjsLo%3D
21. RP Young JC Chan JA Critchley E Poon G Nicholls CS Cockram 1998 Angiotensinogen T235 and ACE insertion/deletion polymorphisms associated with albuminuria in Chinese type 2 diabetic patients Diabetes Care 21 431 437 10.2337/diacare.21.3.431 10.2337/diacare.21.3.431 1:STN:280:DyaK1c3gtVynuw%3D%3D 9540028 (Pubitemid 28101081)
22. MC Hsieh SR Lin TJ Hsieh, et al. 2000 Increased frequency of angiotensin-converting enzyme DD genotype in patients with type 2 diabetes in Taiwan Nephrol Dial Transplant 15 1008 1013 10.1093/ndt/15.7.1008 10.1093/ndt/15.7.1008 1:CAS:528:DC%2BD3cXltFOlurs%3D 10862639
23. A Matsumoto Y Iwashima A Abiko, et al. 2000 Detection of the association between a deletion polymorphism in the gene encoding angiotensin I-converting enzyme and advanced diabetic retinopathy Diabetes Res Clin Pract 50 195 202 10.1016/S0168-8227(00)00194-7 10.1016/S0168-8227(00)00194-7 1:CAS:528: DC%2BD3cXosFeqs7c%3D 11106834
24. M Araz N Yilmaz K Güngör V Okan Y Kepekci A Sükrü Aynacioglu 2001 Angiotensin-converting enzyme gene polymorphism and microvascular complications in Turkish type 2 diabetic patients Diabetes Res Clin Pract 54 95 104 10.1016/S0168-8227(01)00257-1 10.1016/S0168-8227(01)00257-1 1:CAS:528:DC%2BD3MXnsF2htLk%3D 11640993 (Pubitemid 32964680)
25. GN Thomas B Tomlinson JC Chan JE Sanderson CS Cockram JA Critchley 2001 Renin-angiotensin system gene polymorphisms, blood pressure, dyslipidemia, and diabetes in Hong Kong Chinese: a significant association of tne ACE insertion/deletion polymorphism with type 2 diabetes Diabetes Care 24 356 361 10.2337/diacare.24.2.356 10.2337/diacare.24.2.356 1:CAS:528:DC%2BD3MXhtlKgsrg%3D 11213892
26. YJ Lee JC Tsai 2002 ACE gene insertion/deletion polymorphism associated with 1998 World Health Organization definition of metabolic syndrome in Chinese type 2 diabetic patients Diabetes Care 25 1002 1008 10.2337/diacare.25.6.1002 10.2337/diacare.25.6.1002 1:CAS:528:DC%2BD38XkslSksLo%3D 12032106 (Pubitemid 41110485)
27. Y Feng T Niu X Xu, et al. 2002 Insertion/deletion polymorphism of the ACE gene is associated with type 2 diabetes Diabetes 51 1986 1988 10.2337/diabetes.51.6.1986 10.2337/diabetes.51.6.1986 1:CAS:528: DC%2BD38XktlSkurs%3D 12031990
28. M Daimon T Oizumi T Saitoh, et al. 2003 The D allele of the angiotensin-converting enzyme insertion/deletion (I/D) polymorphism is a risk factor for type 2 diabetes in a population-based Japanese sample Endocr J 50 393 398 10.1507/endocrj.50.393 10.1507/endocrj.50.393 1:CAS:528: DC%2BD3sXovFGgs70%3D 14599112 (Pubitemid 37129031)
29. H Arzu Ergen H Hatemi B Agachan H Camlica T Isbir 2004 Angiotensin-I converting enzyme gene polymorphism in Turkish type 2 diabetic patients Exp Mol Med 36 345 350 1:STN:280:DC%2BD2cvnvVSgsw%3D%3D 15365253
30. AH Danser WW Batenburg AH van den Meiracker SM Danilov 2007 ACE phenotyping as a first step toward personalized medicine for ACE inhibitors. Why does ACE genotyping not predict the therapeutic efficacy of ACE inhibition? Pharmacol Ther 113 607 618 10.1016/j.pharmthera.2006.12.001 1:CAS:528: DC%2BD2sXislKjsbw%3D 17257685 (Pubitemid 46365959)
31. I Degirmenci N Kebapci A Basaran, et al. 2005 Frequency of angiotensin-converting enzyme gene polymorphism in Turkish type 2 diabetic patients Int J Clin Pract 59 1137 1142 10.1111/j.1368-5031.2005.00586.x 10.1111/j.1368-5031.2005.00586.x 1:CAS:528:DC%2BD2MXhtFGitbfO 16178979 (Pubitemid 43904518)
32. M Yang CC Qiu Q Xu HD Xiang 2006 Association of angiotensin converting enzyme gene I/D polymorphism with type 2 diabetes mellitus Biomed Environ Sci 19 323 327 1:CAS:528:DC%2BD28XhtF2gs77O 17044652
33. TB Grammer W Renner S von Karger BO Boehm BR Winkelmann W Maerz 2006 The angiotensin-I converting enzyme I/D polymorphism is not associated with type 2 diabetes in individuals undergoing coronary angiography. (The Ludwigshafen Risk and Cardiovascular Health Study) Mol Genet Metab 88 378 383 10.1016/j.ymgme. 2006.01.008 10.1016/j.ymgme.2006.01.008 1:CAS:528:DC%2BD28Xns1Kjs7k%3D 16765625 (Pubitemid 44107763)
34. PP Singh I Naz A Gilmour M Singh S Mastana 2006 Association of APOE (Hha1) and ACE (I/D) gene polymorphisms with type 2 diabetes mellitus in North West India Diabetes Res Clin Pract 74 95 102 10.1016/j.diabres.2006.03.013 10.1016/j.diabres.2006.03.013 1:CAS:528:DC%2BD28XptlyksLg%3D 16621107
35. S Movva RV Alluri S Komandur, et al. 2007 Relationship of angiotensin-converting enzyme gene polymorphism with nephropathy associated with Type 2 diabetes mellitus in Asian Indians J Diabetes Complications 21 237 241 10.1016/j.jdiacomp.2006.07.001 10.1016/j.jdiacomp.2006.07.001 17616353 (Pubitemid 47002317)
36. A Nikzamir M Nakhjavani T Golmohamadi L Dibai 2008 Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with metabolic syndrome in Iranians with type 2 diabetes mellitus Arch Iran Med 11 3 9 1:CAS:528:DC%2BD1cXjt12ktr4%3D 18154415
37. I Arfa A Abid S Nouira, et al. 2008 Lack of association between the angiotensin-converting enzyme gene (I/D) polymorphism and diabetic nephropathy in Tunisian type 2 diabetic patients J Renin Angiotensin Aldosterone Syst 9 32 36 10.3317/jraas.2008.002 10.3317/jraas.2008.002 1:CAS:528:DC%2BD1cXlsFSmur8%3D 18404607 (Pubitemid 351546632)
38. GA Hitman MI McCarthy 1991 Genetics of non-insulin dependent diabetes mellitus Baillieres Clin Endocrinol Metab 5 455 476 10.1016/S0950-351X(05)80142- 9 10.1016/S0950-351X(05)80142-9 1:STN:280:DyaK3MzmvFemtw%3D%3D 1892472
39. P Poulsen KO Kyvik A Vaag H Beck-Nielsen 1999 Heritability of type II (non-insulin-dependent) diabetes mellitus and abnormal glucose tolerance-a population-based twin study Diabetologia 42 139 145 10.1007/s001250051131 10.1007/s001250051131 1:CAS:528:DyaK1MXhtFajsbk%3D 10064092 (Pubitemid 29064234)
40. L Feuk AR Carson SW Scherer 2006 Structural variation in the human genome Nat Rev Genet 7 85 97 10.1038/nrg1767 10.1038/nrg1767 1:CAS:528: DC%2BD28XkvFOjuw%3D%3D 16418744 (Pubitemid 43128895)
41. X Zhu N Bouzekri L Southam, et al. 2001 Linkage and association analysis of angiotensin I-converting enzyme (ACE)-gene polymorphisms with ACE concentration and blood pressure Am J Hum Genet 68 1139 1148 10.1086/320104 10.1086/320104 1:CAS:528:DC%2BD3MXkvF2nur8%3D 11283791 (Pubitemid 32424413)
42. CA McKenzie GR Abecasis B Keavney, et al. 2001 Trans-ethnic fine mapping of a quantitative trait locus for circulating angiotensin I-converting enzyme (ACE) Hum Mol Genet 10 1077 1084 10.1093/hmg/10.10.1077 10.1093/hmg/10.10.1077 1:CAS:528:DC%2BD3MXjslyqtb4%3D 11331618
43. LA Velloso F Folli XJ Sun MF White MJ Saad CR Kahn 1996 Cross-talk between the insulin and angiotensin signaling systems Proc Natl Acad Sci USA 93 12490 12495 10.1073/pnas.93.22.12490 10.1073/pnas.93.22.12490 1:CAS:528:DyaK28Xms1Gisbo%3D 8901609 (Pubitemid 26367171)
44. F Bonnet S Patel M Laville, et al. 2008 European group for the study of insulin resistance relationship between insulin sensitivity and cardiovascular disease risk study group. Influence of the ACE gene insertion/deletion polymorphism on insulin sensitivity and impaired glucose tolerance in healthy subjects Diabetes Care 31 789 794 10.2337/dc07-1788 10.2337/dc07-1788 1:CAS:528:DC%2BD1cXltVKhur4%3D 18235053
45. E Kajantie A Rautanen J Kere, et al. 2004 The effects of the ACE gene insertion/deletion polymorphism on glucose tolerance and insulin secretion in elderly people are modified by birth weight J Clin Endocrinol Metab 89 5738 5741 10.1210/jc.2004-0492 10.1210/jc.2004-0492 1:CAS:528:DC%2BD2cXhtVSisbnP 15531537 (Pubitemid 39518467)
46. PO Carlsson C Berne L Jansson 1998 Angiotensin II and the endocrine pancreas: effects on islet blood flow and insulin secretion in rats Diabetologia 41 127 133 10.1007/s001250050880 10.1007/s001250050880 1:CAS:528: DyaK1cXosl2huw%3D%3D 9498644 (Pubitemid 28088387)
47. C Tikellis PJ Wookey R Candido S Andrikopoulos MC Thomas ME Cooper 2004 Improved islet morphology after blockade of the renin-angiotensin system in the ZDF rat Diabetes 53 989 997 10.2337/diabetes.53.4.989 10.2337/diabetes.53.4.989 1:CAS:528:DC%2BD2cXivFyqsLY%3D 15047614 (Pubitemid 38436611)
48. B Zhang N Shono P Fan, et al. 2005 Histochemical characteristics of soleus muscle in angiotensin-converting enzyme gene knockout mice Hypertens Res 28 681 688 10.1291/hypres.28.681 10.1291/hypres.28.681 1:CAS:528: DC%2BD2MXht12ltLzP 16392773 (Pubitemid 41601042)
49. JP Ioannidis DG Contopoulos-Ioannidis J Lau 1999 Recursive cumulative meta-analysis: a diagnostic for the evolution of total randomized evidence from group and individual patient data J Clin Epidemiol 52 281 291 10.1016/S0895-4356(98)00159-0 10.1016/S0895-4356(98)00159-0 1:STN:280: DyaK1M3kvFantQ%3D%3D 10235168 (Pubitemid 29305300)
50. MJ Rieder SL Taylor AG Clark DA Nickerson 1999 Sequence variation in the human angiotensin converting enzyme Nat Genet 22 59 62 10.1038/8760 10.1038/8760 1:CAS:528:DyaK1MXjtVags7g%3D 10319862 (Pubitemid 29214805)
51. B Keavney CA McKenzie JM Connell, et al. 1998 Measured haplotype analysis of the angiotensin-I converting enzyme gene Hum Mol Genet 7 1745 1751 10.1093/hmg/7.11.1745 10.1093/hmg/7.11.1745 1:CAS:528:DyaK1cXmsVOgtL4%3D 9736776 (Pubitemid 28464149)
52. DPK Ng G Placha S Choo KS Chia JH Warram AS Krolewski 2006 A disease haplotype for advanced nephropathy in type 2 diabetes at the ACE locus Diabetes 55 2660 2663 10.2337/db06-0496 10.2337/db06-0496 1:CAS:528:DC%2BD28XpsVOqs7Y%3D 16936219 (Pubitemid 44871171)
53. S Hadjadj L Tarnow C Forsblom, et al. 2007 The EURAGEDIC (European Rational Approach for Genetics of Diabetic Complications) Study Group: association between angiotensin-converting enzyme gene polymorphisms and diabetic nephropathy: case-control, haplotype, and family-based study in three European populations J Am Soc Nephrol 18 1284 1291 10.1681/ASN.2006101102 10.1681/ASN.2006101102 1:CAS:528:DC%2BD2sXkslSrsbg%3D 17376814 (Pubitemid 46536914)
54. CT Tsai JJ Hwang MD Ritchie, et al. 2007 Renin-angiotensin system gene polymorphisms and coronary artery disease in a large angiographic cohort: detection of high order gene-gene interaction Atherosclerosis 195 172 180 10.1016/j.atherosclerosis.2006.09.014 10.1016/j.atherosclerosis.2006.09.014 1:CAS:528:DC%2BD2sXhtF2hurzN 17118372 (Pubitemid 47561934)
55. S Ye S Dhillon R Seear, et al. 2003 Epistatic interaction between variations in the angiotensin I converting enzyme and angiotensin II type 1 receptor genes in relation to extent of coronary atherosclerosis Heart 89 1195 1199 10.1136/heart.89.10.1195 10.1136/heart.89.10.1195 1:CAS:528: DC%2BD3sXosFaltr0%3D 12975417