Insertion/deletion polymorphism of the angiotensin I-converting enzyme gene in patients with hypertension, non-insulin-dependent diabetes mellitus, and coronary heart disease in Taiwan

Metabolism: Clinical and Experimental

Volumn 46, Issue 10, 1997, Pages 1211-1214

  Chuang, L M ^a   Chiu, K C ^b   Chiang, R T ^b   Lee, K C ^b   Wu, H P ^b   Lin, B J ^b   Tai, T Y ^b  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ADULT; AGED; ALLELISM; ANGIOCARDIOGRAPHY; ARTICLE; CONTROLLED STUDY; GENE DELETION; GENE INSERTION; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; HYPERTENSION; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; TAIWAN;

EID: 0030876426     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(97)90219-5     Document Type: Article

References (30)

1. Ehlers MRW, Riordan JF: Angiotensin-converting enzyme: New concepts concerning its biological role. Biochemistry 28:5311-5318, 1989
2. Tiret L, Rigat B, Visvikis S, et al: Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels. Am J Hum Genet 51:197-205, 1992
3. Villard E, Tiret L, Visvikis S, et al: Identification of new polymorphisms of the angiotensin I - converting enzyme (ACE) gene, and study of their relationship to plasma ACE levels by two-QTL segregation-linkage analysis. Am J Hum Genet 58:1268-1278, 1996
4. Lieberman J, Sastre A: Serum angiotensin-converting enzyme: Elevations in diabetes mellitus. Ann Intern Med 93:825-826, 1980
5. Ninimiya Y, Arakawa M: Serum angiotensin-converting enzyme activity in type 2 (non-insulin-dependent) diabetic patients with chronic glomerulonephritis. Diabetes Res 11:121-124, 1989
6. Migdalis IN, Ilipoulou V, Kalogeropoulou K, et al: Elevated serum levels of angiotensin-converting enzyme in patients with diabetic retinopathy. South Med J 83:425-427, 1990
7. Townsend RR, DiPette D: Pressor doses of angiotensin II increased insulin-mediated glucose uptake in normotensive men. Am J Physiol 265:E362-E366, 1993
8. Widgren BR, Urbananvicius V, Wikstrand J, et al: Low-dose angiotensin II increases glucose deposition rate during euglycemic hyperinsulinemia. Am J Hyperten 6:892-895, 1993
9. Morris AD, Petrie JR, Ueda S, et al: Angiotensin II increases insulin sensitivity in non-insulin-dependent diabetes: Dissociation of metabolic and blood pressure effects. Diabetes 43:1445-1449, 1994
10. Jauch K-W, Hartl W, Guenther B, Wicklmayr M, Rett K, Dietze G: Captopril enhances insulin responsiveness of forearm muscle tissue in non-insulin-dependent diabetes mellitus. Eur J Clin Invest 17:448-454, 1987
11. Allemann Y, Baumann S, Jost M, et al: Insulin sensitivity in normotensive subjects during angiotensin converting enzyme inhibition with fosinopril. Eur J Clin Pharmacol 42:275-280, 1992
12. Moan A, Hoieggen A, Nordby G, et al: Effects of losartan on insulin sensitivity in severe hypertension: Connections through sympathetic nervous system activity? J Hum Hypertens 9:S45-S50, 1995 (suppl 5)
13. Zee RY, Lou YK, Griffiths LR, et al: Association of a polymorphism of the angiotensin I-converting enzyme gene with essential hypertension. Biochem Biophys Res Commun 184:9-15, 1992
14. Cambien F, Poieier O, Lecerf L, et al: Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction. Nature 359:641-644, 1992
15. Ruiz J, Blanche H, Cohen N, et al: Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is strongly associated with coronary heart disease in non-insulin-dependent diabetes mellitus. Proc Natl Acad Sci USA 91:3662-3665, 1994
16. Doria A, Warram JH, Krolewski AS: Genetic predisposition to diabetic nephropathy. Evidence for a role of the angiotensin I-converting enzyme gene. Diabetes 43:690-695, 1994
17. Fujisawa T, Ikegami H, Shen GQ, et al: Angiotensin I-converting enzyme gene polymorphism is associated with myocardial infarction, but not with retinopathy or nephropathy, in NIDDM. Diabetes Care 18:983-985, 1995
18. Nagi DK, Mansfield MW, Stickland MH, et al: Angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism, and diabetic retinopathy in subjects with IDDM and NIDDM. Diabetic Med 12:997-1001, 1995
19. Panahloo A, Andres C, Mohamed-Ali V, et al: The insertion allele of the ACE gene I/D polymorphism. A candidate gene for insulin resistance? Circulation 92:3390-3393, 1995
20. Fogarty DG, Maxwell AP, Doherty CC, et al: ACE gene typing. Lancet 343:851, 1994 (letter)
21. Chiu KC, McCarthy JE: The insertion allele at the angiotensin I converting enzyme gene locus is associated with insulin resistance. Metabolism 46:395-399, 1997
22. Barley J, Blackwood A, Carter ND, et al: Angiotensin converting enzyme insertion/deletion polymorphism: Association with ethnic origin. J Hypertens 12:955-957, 1994
23. Bloem LJ, Manatunga AK, Pratt JH: Racial difference in the relationship of an angiotensin I - converting enzyme gene polymorphism to serum angiotensin I - converting enzyme activity. Hypertension 27:62-66, 1996
24. Ishigami T, Iwamoto T, Tamura K, et al: Angiotensin I converting enzyme (ACE) gene polymorphism and essential hypertension in Japan. Ethnic difference of ACE genotype. Am J Hypertens 8:95-97, 1995
25. Lee EJD: Population genetics of the angiotensin-converting enzyme in Chinese. Br J Clin Pharmacol 37:212-214, 1994
26. Winkelmann BR, Nauck M, Klein B, et al: Deletion polymorphism of the angiotensin I - converting enzyme gene is associated with increased plasma angiotensin-converting enzyme activity but not with increased risk for myocardial infarction and coronary artery disease. Ann Intern Med 125:19-25, 1996
27. Bernhardt R, Feng A, Deng Y, et al: Incidence and mortality rates of myocardial infarction in Chinese workers aged 40-59 in relation to coronary risk factors. Results of a Chinese prospective study (Wuhan Study) in comparison to the Gottingen Risk Incidence and Prevalence Study (GRIPS). Klin Wochenschr 69:201-212, 1991
28. Ducimetie're P, Richard JL, Cambien F, et al: Coronary heart disease in middle-aged Frenchmen. Comparison between Paris Prospective Study, Seven Countries Study, and Pooling Project. Lancet 1:1346-1350, 1980
29. Reaven GM, Lithell H, Landsberg L: Hypertension and associated metabolic abnormalities - The role of insulin resistance and the sympathoadrenal system. N Engl J Med 334:374-381, 1996
30. Chiang FT, Lai ZP, Tseng CD, et al: Lack of association between angiotensin-converting enzyme and essential hypertension in a Chinese population. Am J Hypertens 10:197-201, 1997