The effects of the ACE gene insertion/deletion polymorphism on glucose tolerance and insulin secretion in elderly people are modified by birth weight

Journal of Clinical Endocrinology and Metabolism

Volumn 89, Issue 11, 2004, Pages 5738-5741

  Kajantie, Eero ^a,b,e   Rautanen, Anna ^c   Kere, Juha ^c,d   Andersson, Sture ^b   Ylihärsilä, Hilkka ^a   Osmond, Clive ^e   Barker, David J P ^e   Forsén, Tom ^a   Eriksson, Johan ^a  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d KAROLINSKA INSTITUTE   (Sweden)

^e SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE; GLUCOSE; INSULIN;

AGED; ALLELE; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; ELDERLY CARE; FEMALE; GENE DELETION; GENE INSERTION; GESTATIONAL AGE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; HIGH BIRTH WEIGHT; HUMAN; INSULIN RELEASE; INSULIN RESISTANCE; LOW BIRTH WEIGHT; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

BIRTH WEIGHT; FEMALE; GENE DELETION; GENOTYPE; GLUCOSE TOLERANCE TEST; HUMANS; INFANT, NEWBORN; INSULIN; MALE; MIDDLE AGED; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC;

INSERTION SEQUENCES;

EID: 8744243269     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2004-0492     Document Type: Article

References (24)

1. Hales CN, Barker DJP, Clark PMS, Cox LJ, Fall C, Osmond C, Winter PD 1991 Fetal and infant growth and impaired glucose tolerance at age 64. BMJ 303: 1019-1022
2. Phillips DIW 1996 Insulin resistance as a programmed response to fetal undernutrition. Diabetologia 39:1119-1122
3. Forsén T, Eriksson J, Tuomilehto J, Reunanen A, Osmond C, Barker D 2000 The fetal and childhood growth of persons who develop type 2 diabetes. Ann Intern Med 133:176-182
4. Newsome CA, Shiell AW, Fall CH, Phillips DI, Shier R, Law CM 2003 Is birth weight related to later glucose and insulin metabolism? A systematic review. Diabet Med 20:339-348
5. Eriksson JG, Forsén T, Tuomilehto J, Jaddoe VWV, Osmond C, Barker DJP 2002 Effects of size at birth and childhood growth on the insulin resistance syndrome in elderly individuals. Diabetologia 45:342-348
6. West-Eberhard MJ 1989 Phenotypic plasticity and the origins of diversity. Annu Rev Ecol Syst 20:249-278
7. Barker DJP 2002 Components in the interpretation of the high mortality in the county of Finnmark. Int J Epidemiol 31:309-310
8. Harding JE 2001 The nutritional basis of the fetal origins of adult disease. Int J Epidemiol 30:15-23
9. Cambien F, Léger, J, Mallet C, Lévy-Marchal C, Collin D, Czernichow P 1998 Angiotensin I-converting enzyme gene modulated the consequences of in utero growth retardation on plasma insulin in young adults. Diabetes 47:470-475
10. Dennison E, Arden NK, Keen RW, Syddall H, Day INM, Spector TD, Cooper C 2001 Birthweight, vitamin D receptor genotype and the programming of osteoporosis. Paediatr Perinat Epidemiol 15:211-219
11. Eriksson JG, Lindi V, Uusitupa M, Forsén TJ, Laakso M, Osmond C, Barker DJP 2002 The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-γ2 gene on insulin sensitivity and insulin metabolism interact with size at birth. Diabetes 51:2321-2324
12. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol B, Soubrier F 1990 An insertion-deletion polymorphism in the angiotensin I converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest 86: 1343-1346
13. Danser AHJ, Schalekamp MADH, Bax WA, van den Brink AM, Saxena PR, Riegger GAJ, Schumkert H 1995 Angiotensin-converting enzyme in the human heart: effect of the deletion/insertion polymorphism. Circulation 92: 1387-1388
14. Kennon B, Petrie JR, Small M, Connell JMC 1999 Angiotensin-converting enzyme gene and diabetes mellitus. Diabet Med 16:448-458
15. Ruiz J, Blanche H, Cohen N, Cambien F, Cohen D, Passa P, Froguel P 1994 Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is strongly associated with coronary heart disease in non insulin-dependent diabetes mellitus. Proc Natl Acad Sci USA 91:3662-3665
16. Huang XH, Rantalaiho V, Wirta O, Pasternack A, Koivula T, Hiltunen TP, Nikkari T, Lehtimaki T 1998 Angiotensin-converting enzyme gene polymorphism is associated with coronary heart disease in non-insulin-dependent diabetic patients evaluated for 9 years. Metabolism 47:1258-1262
17. Morgan TM, Coffey CS, Krumholz HM 2003 Overestimation of genetic risks owing to small sample sizes in cardiovascular studies. Clin Genet 64:7-17
18. Forsén T, Eriksson JG, Tuomilehto J, Teramo K, Osmond C, Barker DJ 1997 Mother's weight in pregnancy and coronary heart disease: longitudinal study. BMJ 315:837-840
19. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC 1985 Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412-419
20. Alberti KGMM, Zimmet PZ for the WHO consultation 1998 Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation. Diabet Med 15:539-553
21. Mello G, Parretti E, Gensini F, Sticchi E, Macacci F, Scaraselli G, Genuardi M, Abbate R, Fatini C 2003 Maternal-fetal flow, negative events, and preeclampsia - role of ACE I/D polymorphism. Hypertension 41:932-937
22. Aerts L, Van Assche FA 1977 Rat foetal endocrine pancreas in experimental diabetes. J Endocrinol 73:339-346
23. Ito M, Itakura A, Ohno Y, Nomura M, Senga T, Nagasaka T, Mizutani S 2002 Possible activation of the renin-angiotensin system in the feto-placental unit in preeclampsia. J Clin Endocrinol Metab 87:1871-1878
24. Kramer MS, McLean FH, Boyd ME, Usher RH 1988 The validity of gestational age estimation by menstrual dating in term, preterm, and postterm gestations. JAMA 260:3306-3308