Process considerations for the scale-up and implementation of biocatalysis

Food and Bioproducts Processing

Volumn 88, Issue 1, 2010, Pages 3-11

  Tufvesson, Pär ^a   Fu, Wenjing ^a   Jensen, Jacob Skibsted ^a   Woodley, John M ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Biocatalysis; Process design; Reactors; Scale up

Indexed keywords

BIOCATALYSIS; BIOCATALYTIC PROCESS; BIOPROCESSES; CHEMICAL PRODUCTION; DEVELOPMENT PROCESS; ENGINEERING TOOLS; GREEN CHEMISTRY; INDUSTRIAL CHEMISTRY; INDUSTRIAL PROCESSS; NEW PROCESS; PHARMACEUTICAL INDUSTRY; SCALE-UP;

CHEMICAL CONTAMINATION; DESIGN; DRUG PRODUCTS PLANTS;

PROCESS DESIGN;

EID: 77949261554     PISSN: 09603085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fbp.2010.01.003     Document Type: Article

References (63)

1. Alvarado-Morales M., Terra J., Gernaey K.V., Woodley J.M., and Gani R. Biorefining: Computer aided tools for sustainable design and analysis of bioethanol production. Chemical Engineering Research and Development 87 (2009) 1171-1183
2. Blayer S., Woodley J.M., and Lilly M.D. Characterization of the chemoenzymatic synthesis of N-acetyl-d-neuraminic acid (Neu5Ac). Biotechnology Progress 12 (1996) 758-763
3. Bühler B., Straathof A.J., Witholt B., and Schmid A. Analysis of two-liquid-phase multistep biooxidation based on a process model: indications for biological energy shortage. Organic Process Research and Development 10 (2006) 628-643
4. Balcão V.M., Paiva A.L., and Malcata F.X. Bioreactors with immobilized lipases: state of the art. Enzyme & Microbial Technology 18 (1996) 392-416
5. Baldwin C.V.F., Wohlgemuth R., and Woodley J.M. The first 200 L scale asymmetric Baeyer-Villiger oxidation using a whole-cell biocatalyst. Organic Process Research and Development 12 (2008) 660-665
6. Biwer A., Griffith S., and Cooney C. Uncertainty analysis of Penicillin V production using Monte Carlo simulation. Biotechnology and Bioengineering 90 (2005) 167-179
7. Bornscheuer U.T. Immobilizing enzymes: how to create more suitable biocatalysts. Angewandte Chemie International Edition 43 (2003) 3336-3337
8. Bosley J.A., and Peilow A.D. Immobilization of lipases on porous polypropylene: reduction in esterification efficiency at low loading. Journal of the American Oil Chemists' Society 74 (1997) 107-111
9. Burton S.G., Cowan D.A., and Woodley J.M. The search for the ideal biocatalyst. Nature 20 (2002) 37-45
10. Cao L., van Langen L., and Sheldon R. Immobilised enzymes: carrier-bound or carrier-free?. Current Opinion in Biotechnology 14 (2003) 387-394
11. Diky V., Muzny C.D., Lemmon E.W., Chirico R.D., and Frenkel M. ThermoData Engine (TDE): software implementation of the dynamic data evaluation concept. 2. Equations of state on-demand and dynamic updates over the web. Journal of Chemical Information and Modeling 47 (2007) 1713-1725
12. Durany O., de Mas C., and Lopez-Santin J. Fed-batch production of recombinant fuculose-1-phosphate aldolase in E. coli. Process Biochemistry 40 (2005)
13. El-Mansi E.M.T., Bryce C.F.A., Demain A.L., and Allman A.R. Fermentation Microbiology and Biotechnology (2006), Taylor & Francis Ltd., London
14. Fogler H.S. Elements of Chemical Reaction Engineering. 4th edn. (2006), Pearson Education Inc., Upper Saddle River, NJ
15. Fox R.J., and Huisman G.W. Enzyme optimization: moving from blind evolution to statistical exploration of sequence-function space. Trends in Biotechnology 26 (2008) 132-137
16. Frazzetto G. White Biotechnology. EMBO Reports 4 (2003) 835-837
17. Fernandes J.F.A., McAlpine M., and Halling P.J. Operational stability of subtilisin CLECs in organic solvents in repeated batch and in continuous operation. Biochemical Engineering Journal 24 (2005) 11-15
18. Gani R., Hytoft G., Jaksland C., and Jensen A.K. An integrated computer aided system for integrated design of chemical processes. Computers in Chemical Engineering 21 (1997) 1135-1146
19. Hanefeld U., Gardossi L., and Magner E. Understanding enzyme immobilisation. Chemical Society Reviews 38 (2009) 453-468
20. Hatti-Kaul R., Törnvall U., Gustafsson L., and Börjesson P. Industrial biotechnology for the production of bio-based chemicals-a cradle-to-grave perspective. Trends in Biotechnology 25 (2007) 119-124
21. Henderson R.K., Jimenez-Gonzalez C., Preston C., Constable D.J.C., and Woodley J.M. Comparison of biocatalytic and chemical synthesis: EHS and LCA comparison for 7-ACA synthesis. Industrial Biotechnology 4 (2008) 180-192
22. Hilterhaus L., Thum O., and Liese A. Reactor concept for lipase-catalyzed solvent-free conversion of highly viscous reactants forming two-phase systems. Organic Process Research & Development 12 (2008) 618-625
23. Hills G. Industrial use of lipases to produce fatty acid ester. European Journal of Lipid Science and Technology 105 (2003) 601-607
24. Huisman, G., 2009, Codexis, Personal communication, Redwood, CA.
25. IB-IGT. IB 2025 Maximizing UK opportunities from industrial biotechnology in a low carbon economy (2009). http://www.berr.gov.uk/files/file51144.pdf
26. ISO. ISO 14040-43, Life Cycle Assessment (1998), International Organization for Standardization, Geneva
27. Jaeger K.-E. Protein technologies and commercial enzymes: White is the hype-biocatalysts on the move. Current Opinion in Biotechnology 15 (2004) 269-271
28. Kirk O., Borchert T.V., and Fuglsang C.C. Industrial enzyme applications. Current Opinion in Biotechnology 13 (2002) 345-351
29. Kirk O., and Christensen M.W. Lipases from Candida antarctica: unique biocatalysts from a unique origin. Organic Process Research & Development 6 (2002) 446-451
30. Kim S., Jiménez-González C., and Dale B.E. Enzymes for pharmaceutical applications-a cradle-to-gate life cycle assessment. International Journal of Life Cycle Assessment 14 (2009) 392-400
31. Law H.E.M., Baldwin C.V.F., Chen B.H., and Woodley J. Process limitations in a whole-cell catalysed oxidation: sensitivity analysis. Chemical Engineering Science 61 (2006) 6646-6652
32. Law H.E.M., Lewis D.J., McRobbie I., and Woodley J. Model visualization for evaluation of biocatalytic processes. Food and Bioproducts Processing 86 (2008) 96-103
33. Lee S.Y. High cell-density culture of Escherichia coli. Trends in biotechnology 14 (1996) 98-105
34. Liese A., Seelbach K., and Wandrey C. Industrial Biotransformations (2006), Wiley-VCH, Weinheim
35. Lilly M.D., and Woodley J.M. A structured approach to design and operation of biotransformation processes. Journal of Industrial Microbiology 17 (1996) 24-29
36. Marquardt W. Systems problems in biorenewables processing. In: de Brito Alves R.M., do Nascimento C.A.O., and Biscaia Jr. E.V. (Eds). Proceedings of the 10th International Symposium Process System Engineering (2009) 35-40
37. Martin A., DiSanto R., Plotnikov I., Kamat S., Shonnard D., and Pannuri S. Improved activity and thermostability of (S)-aminotransferase by error-prone polymerase chain reaction for the production of a chiral amine. Biochemical Engineering Journal 37 (2007) 246-255
38. Nielsen P.M., Brask J., and Fjerbaek L. Enzymatic biodiesel production: technical and economical considerations. European Journal of Lipid Science and Technology 110 (2008) 692-700
39. Petersson A.E.V., Gustafsson L.M., Nordblad M., Borjesson P., Mattiasson B., and Adlercreutz P. Wax esters produced by solvent-free energy-efficient enzymatic synthesis and their applicability as wood coatings. Green Chemistry 7 (2005) 837-843
40. Pollard D.J., and Woodley J.M. Biocatalysis for pharmaceutical intermediates: the future is now. Trends in Biotechnology 25 (2007) 66-73
41. Reetz M.T. Directed evolution of enantioselective enzymes: an unconventional approach to asymmetric catalysis in organic chemistry. Journal of Organic Chemistry 74 (2009) 5767-5778
42. Reetz M.T., Wang L.-W., and Bocola M. Directed evolution of enantioselective enzymes: iterative cycles of CASTing for probing protein-sequence space. Angewandte Chemie International Edition 45 (2006) 1236-1241
43. Rozzell D.J. Commercial scale biocatalysis: myths and realities. Bioorganic & Medicinal Chemistry 7 (1999) 2253-2261
44. Saltelli A., Ratto M., Tarantola S., and Campolongo F. Sensitivity analysis for chemical models. Chemical Reviews 105 (2005) 2811-2827
45. Sammons N., Eden M., Cullinan H., Perine L., and Connor E. A flexible framework for optional biorefinery product allocation. Environmental Progress 26 (2007) 349-354
46. Schmid A., Dordick J.S., Hauer B., Kiener A., Wubbolts M., and Witholt B. Industrial biocatalysis today and tomorrow. Nature 409 (2001) 258-268
47. Schmid A., Hollmann F., Park J.B., and Bühler B. The use of enzymes in the chemical industry in Europe. Current Opinion in Biotechnology 13 (2002) 359-366
48. Schoevaart, R., 2009, ChiralVision, Personal communication, Leiden The Netherlands.
49. Sheldon R.A. Enzyme immobilization: the quest for optimum performance. Advanced Synthesis & Catalysis 349 (2007) 1289-1307
50. Shimada Y., Watanabe Y., Sugihara A., and Tominaga Y. Enzymatic alcoholysis for biodiesel fuel production and application of the reaction to oil processing. Journal of Molecular Catalysis B: Enzymatic 17 (2002) 133-142
51. Sin G., Woodley J.M., and Gernaey K.V. Application of modeling and simulation tools for the evaluation of biocatalytic processes: a future perspective. Biotechnology Progress 25 (2009) 1529-1538
52. Straathof A.J.J., Panke S., and Schmid A. The production of fine chemicals by biotransformations. Current Opinion in Biotechnology 13 (2002) 548-556
53. Thum O., and Oxenbøl K.M. Biocatalysis: a sustainable process for production of cosmetic ingredients. SÖFW Journal: International Journal for Applied Science (English edition) 134 (2008) 44-47
54. Tracewell C.A., and Arnold F.H. Directed evolution: climbing fitness peaks one amino acid at a time. Current Opinion in Chemical Biology 13 (2009) 3-9
55. Turner N.J. Directed evolution drives the next generation of biocatalysts. Nature Chemical Biology 5 (2009) 567-573
56. Thiry M., and Cingolani D. Optimizing scale-up fermentation processes. Trends in Biotechnology 20 (2002) 103-105
57. Vidal L., Ferrer P., Alvaro G., Benaiges M.D., and Caminal G. Influence of induction and operation mode on recombinant rhamnulose 1-phosphate aldolase production by Escherichia coli using the T5 promoter. Journal of Biotechnology 118 (2005) 75-87
58. Vogel A. Use of cluster-screening for the identification of new, customized enzymes in natural and artificial diversity. Oral Presentation at 8th International Symposium on Biocatalysis and Biotransformations. Oviedo, Spain (2007)
59. Watanabe T., Sugiura M., Sato M., Yamada N., and Nakanishi K. Diacylglycerol production in packed bed bioreactor. Process Biochemistry 40 (2005) 637-643
60. Woodley J.M., and Lilly M.D. Biotransformation reactor selection and operation. In: Cabral J.M.S., Best D., and Tramper J. (Eds). Applied Biocatalysis (1994), Harwood Academic, Chur, Switzerland
61. Woodley J.M., and Titchener-Hooker N.J. The use of windows of operation as a bioprocess design tool. Bioprocess Engineering 14 (1996) 263-268
62. Woodley J.M. Microbial biocatalytic processes and their development. Advances in Applied Microbiology 60 (2006) 1-15
63. Xu X. Engineering of enzymatic reactions and reactors for lipid modification and synthesis. European Journal of Lipid Science and Technology 105 (2003) 289-304