메뉴 건너뛰기




Volumn 36, Issue 4, 2010, Pages 809-816

Radiation-inducible silencing of uPA and uPAR in vitro and in vivo in meningioma

Author keywords

CArG elements; Meningioma; Radiation inducible promoter; siRNA; uPA; uPAR

Indexed keywords

ACETYLCYSTEINE; HYDROGEN PEROXIDE; MATRIGEL; PLASMID VECTOR; PLASMID VECTOR PCARG; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 77749333027     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo-00000557     Document Type: Article
Times cited : (13)

References (35)
  • 1
    • 33748995139 scopus 로고    scopus 로고
    • Ionizing radiation enhances matrix metalloproteinase-2 secretion and invasion of glioma cells through Src/epidermal growth factor receptor-mediated p38/Akt and phosphatidylinositol 3-kinase/Akt signaling pathways
    • Park CM, Park MJ, Kwak HJ, Lee HC, Kim MS, Lee SH, Park IC, Rhee CH and Hong SI: Ionizing radiation enhances matrix metalloproteinase-2 secretion and invasion of glioma cells through Src/epidermal growth factor receptor-mediated p38/Akt and phosphatidylinositol 3-kinase/Akt signaling pathways. Cancer Res 66: 8511-8519, 2006.
    • (2006) Cancer Res , vol.66 , pp. 8511-8519
    • Park, C.M.1    Park, M.J.2    Kwak, H.J.3    Lee, H.C.4    Kim, M.S.5    Lee, S.H.6    Park, I.C.7    Rhee, C.H.8    Hong, S.I.9
  • 4
    • 3242798679 scopus 로고    scopus 로고
    • Use of the radiation-inducible WAF1 promoter to drive iNOS gene therapy as a novel anti-cancer treatment
    • Worthington J, McCarthy HO, Barrett E, Adams C, Robson T and Hirst DG: Use of the radiation-inducible WAF1 promoter to drive iNOS gene therapy as a novel anti-cancer treatment. J Gene Med 6: 673-680, 2004.
    • (2004) J Gene Med , vol.6 , pp. 673-680
    • Worthington, J.1    McCarthy, H.O.2    Barrett, E.3    Adams, C.4    Robson, T.5    Hirst, D.G.6
  • 10
    • 0028281871 scopus 로고
    • Isolation of an X-ray-responsive element in the promoter region of tissue-type plasminogen activator: Potential uses of X-ray-responsive elements for gene therapy
    • Boothman DA, Lee IW and Sahijdak WM: Isolation of an X-ray-responsive element in the promoter region of tissue-type plasminogen activator: potential uses of X-ray-responsive elements for gene therapy. Radiat Res 138: S68-S71, 1994.
    • (1994) Radiat Res , vol.138
    • Boothman, D.A.1    Lee, I.W.2    Sahijdak, W.M.3
  • 11
    • 31444439776 scopus 로고    scopus 로고
    • Hypoxia- and radiation-activated Cre/loxP 'molecular switch' vectors for gene therapy of cancer
    • Greco O, Joiner MC, Doleh A, Powell AD, Hillman GG and Scott SD: Hypoxia- and radiation-activated Cre/loxP 'molecular switch' vectors for gene therapy of cancer. Gene Ther 13: 206-215, 2006.
    • (2006) Gene Ther , vol.13 , pp. 206-215
    • Greco, O.1    Joiner, M.C.2    Doleh, A.3    Powell, A.D.4    Hillman, G.G.5    Scott, S.D.6
  • 12
    • 0036845222 scopus 로고    scopus 로고
    • Radiation-induced tumour necrosis factor-alpha expression: Clinical application of transcriptional and physical targeting of gene therapy
    • Weichselbaum RR, Kufe DW, Hellman S, Rasmussen HS, King CR, Fischer PH and Mauceri HJ: Radiation-induced tumour necrosis factor-alpha expression: clinical application of transcriptional and physical targeting of gene therapy. Lancet Oncol 3: 665-671, 2002.
    • (2002) Lancet Oncol , vol.3 , pp. 665-671
    • Weichselbaum, R.R.1    Kufe, D.W.2    Hellman, S.3    Rasmussen, H.S.4    King, C.R.5    Fischer, P.H.6    Mauceri, H.J.7
  • 14
    • 0029559345 scopus 로고
    • Activation of the radiosensitive EGR-1 promoter induces expression of the herpes simplex virus thymidine kinase gene and sensitivity of human glioma cells to ganciclovir
    • Joki T, Nakamura M and Ohno T: Activation of the radiosensitive EGR-1 promoter induces expression of the herpes simplex virus thymidine kinase gene and sensitivity of human glioma cells to ganciclovir. Hum Gene Ther 6: 1507-1513, 1995.
    • (1995) Hum Gene Ther , vol.6 , pp. 1507-1513
    • Joki, T.1    Nakamura, M.2    Ohno, T.3
  • 15
    • 0036773207 scopus 로고    scopus 로고
    • Optimizing radiation-responsive gene promoters for radiogenetic cancer therapy
    • Scott SD, Joiner MC and Marples B: Optimizing radiation-responsive gene promoters for radiogenetic cancer therapy. Gene Ther 9: 1396-1402, 2002.
    • (2002) Gene Ther , vol.9 , pp. 1396-1402
    • Scott, S.D.1    Joiner, M.C.2    Marples, B.3
  • 16
    • 40949114493 scopus 로고    scopus 로고
    • The radiation-inducible pE9 promoter driving inducible nitric oxide synthase radiosensitizes hypoxic tumour cells to radiation
    • Coulter JA, McCarthy HO, Worthington J, Robson T, Scott S and Hirst DG: The radiation-inducible pE9 promoter driving inducible nitric oxide synthase radiosensitizes hypoxic tumour cells to radiation. Gene Ther 15: 495-503, 2008.
    • (2008) Gene Ther , vol.15 , pp. 495-503
    • Coulter, J.A.1    McCarthy, H.O.2    Worthington, J.3    Robson, T.4    Scott, S.5    Hirst, D.G.6
  • 17
    • 85022917932 scopus 로고    scopus 로고
    • Downregulation of uPA, uPAR and MMP-9 using small, interfering, hairpin RNA (siRNA) inhibits glioma cell invasion, angiogenesis and tumor growth
    • Gondi CS, Lakka SS, Dinh D, Olivero W, Gujrati M and Rao JS: Downregulation of uPA, uPAR and MMP-9 using small, interfering, hairpin RNA (siRNA) inhibits glioma cell invasion, angiogenesis and tumor growth. Neuron Glia Biol 1: 165-176, 2004.
    • (2004) Neuron Glia Biol , vol.1 , pp. 165-176
    • Gondi, C.S.1    Lakka, S.S.2    Dinh, D.3    Olivero, W.4    Gujrati, M.5    Rao, J.S.6
  • 19
    • 27744435789 scopus 로고    scopus 로고
    • RNA Interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo
    • Pulukuri SM, Gondi CS, Lakka SS, Jutla A, Estes N, Gujrati M and Rao JS: RNA Interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivo. J Biol Chem 280: 36529-36540, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 36529-36540
    • Pulukuri, S.M.1    Gondi, C.S.2    Lakka, S.S.3    Jutla, A.4    Estes, N.5    Gujrati, M.6    Rao, J.S.7
  • 20
    • 0033026635 scopus 로고    scopus 로고
    • Urokinase plasminogen activator: A prognostic marker in multiple types of cancer
    • Duffy MJ, Maguire TM, McDermott EW and O'Higgins N: Urokinase plasminogen activator: a prognostic marker in multiple types of cancer. J Surg Oncol 71: 130-135, 1999.
    • (1999) J Surg Oncol , vol.71 , pp. 130-135
    • Duffy, M.J.1    Maguire, T.M.2    McDermott, E.W.3    O'Higgins, N.4
  • 22
    • 64549083733 scopus 로고    scopus 로고
    • Therapeutic potential of siRNA-mediated targeting of urokinase plasminogen activator, its receptor, and matrix metalloproteinases
    • Gondi CS and Rao JS: Therapeutic potential of siRNA-mediated targeting of urokinase plasminogen activator, its receptor, and matrix metalloproteinases. Methods Mol Biol 487: 267-281, 2009.
    • (2009) Methods Mol Biol , vol.487 , pp. 267-281
    • Gondi, C.S.1    Rao, J.S.2
  • 23
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P and Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987.
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 24
    • 34547095270 scopus 로고    scopus 로고
    • Small interfering RNA directed reversal of urokinase plasminogen activator demethylation inhibits prostate tumor growth and metastasis
    • Pulukuri SM and Rao JS: Small interfering RNA directed reversal of urokinase plasminogen activator demethylation inhibits prostate tumor growth and metastasis. Cancer Res 67: 6637-6646, 2007.
    • (2007) Cancer Res , vol.67 , pp. 6637-6646
    • Pulukuri, S.M.1    Rao, J.S.2
  • 25
    • 0141841681 scopus 로고    scopus 로고
    • Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis
    • Gondi CS, Lakka SS, Yanamandra N, Siddique K, Dinh DH, Olivero WC, Gujrati M and Rao JS: Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis. Oncogene 22: 5967-5975, 2003.
    • (2003) Oncogene , vol.22 , pp. 5967-5975
    • Gondi, C.S.1    Lakka, S.S.2    Yanamandra, N.3    Siddique, K.4    Dinh, D.H.5    Olivero, W.C.6    Gujrati, M.7    Rao, J.S.8
  • 26
    • 60749137517 scopus 로고    scopus 로고
    • RNAi-mediated downregulation of radiation-induced MMP-9 leads to apoptosis via activation of ERK and Akt in IOMM-Lee cells
    • Gogineni VR, Kargiotis O, Klopfenstein JD, Gujrati M, Dinh DH and Rao JS: RNAi-mediated downregulation of radiation-induced MMP-9 leads to apoptosis via activation of ERK and Akt in IOMM-Lee cells. Int J Oncol 34: 209-218, 2009.
    • (2009) Int J Oncol , vol.34 , pp. 209-218
    • Gogineni, V.R.1    Kargiotis, O.2    Klopfenstein, J.D.3    Gujrati, M.4    Dinh, D.H.5    Rao, J.S.6
  • 27
    • 34547134691 scopus 로고    scopus 로고
    • Intraperitoneal injection of an hpRNA-expressing plasmid targeting uPAR and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice
    • Gondi CS, Lakka SS, Dinh DH, Olivero WC, Gujrati M and Rao JS: Intraperitoneal injection of an hpRNA-expressing plasmid targeting uPAR and uPA retards angiogenesis and inhibits intracranial tumor growth in nude mice. Clin Cancer Res 13: 4051-4060, 2007.
    • (2007) Clin Cancer Res , vol.13 , pp. 4051-4060
    • Gondi, C.S.1    Lakka, S.S.2    Dinh, D.H.3    Olivero, W.C.4    Gujrati, M.5    Rao, J.S.6
  • 28
    • 35348905119 scopus 로고    scopus 로고
    • RNAi-mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease-9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth
    • Kunigal S, Lakka SS, Gondi CS, Estes N and Rao JS: RNAi-mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease-9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth. Int J Cancer 121: 2307-2316, 2007.
    • (2007) Int J Cancer , vol.121 , pp. 2307-2316
    • Kunigal, S.1    Lakka, S.S.2    Gondi, C.S.3    Estes, N.4    Rao, J.S.5
  • 33
    • 0027512020 scopus 로고
    • Reactive oxygen intermediates target CC(A/T) 6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation
    • Datta R, Taneja N, Sukhatme VP, Qureshi SA, Weichselbaum R and Kufe DW: Reactive oxygen intermediates target CC(A/T) 6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation. Proc Natl Acad Sci USA 90: 2419-2422, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 2419-2422
    • Datta, R.1    Taneja, N.2    Sukhatme, V.P.3    Qureshi, S.A.4    Weichselbaum, R.5    Kufe, D.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.