The radiation-inducible pE9 promoter driving inducible nitric oxide synthase radiosensitizes hypoxic tumour cells to radiation

Gene Therapy

Volumn 15, Issue 7, 2008, Pages 495-503

  Coulter, J A ^a   McCarthy, H O ^a   Worthington, J ^b   Robson, T ^a   Scott, S ^c   Hirst, D G ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b UNIVERSITY OF ULSTER   (United Kingdom)

^c MEDWAY SCHOOL OF PHARMACY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; OXYGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GENE THERAPY; CANCER INHIBITION; CELL HYPOXIA; CONTROLLED STUDY; CYTOMEGALOVIRUS; EXPRESSION VECTOR; FEMALE; FIBROSARCOMA; GENE ACTIVITY; GENE CONSTRUCT; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RADIATION DOSE; RADIOSENSITIZATION; SARCOMA CELL; TRANSGENE; TUMOR CELL; X RAY;

ANIMALS; CELL HYPOXIA; CELL LINE, TUMOR; COMBINED MODALITY THERAPY; CYTOMEGALOVIRUS; FEMALE; FIBROSARCOMA; GENE THERAPY; MICE; MICE, INBRED C3H; NEOPLASMS; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PROMOTER REGIONS (GENETICS); RADIATION-SENSITIZING AGENTS; TRANSFECTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

CYTOMEGALOVIRUS;

EID: 40949114493     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2008.7     Document Type: Article

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