Radiation-Inducible Caspase-8 Gene Therapy for Malignant Brain Tumors

International Journal of Radiation Oncology Biology Physics

Volumn 71, Issue 2, 2008, Pages 517-525

  Tsurushima, Hideo ^a,c   Yuan, Xuan ^b   Dillehay, Larry E ^b   Leong, Kam W ^a  

^a Johns Hopkins University   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Caspase 8 gene therapy; Combined gene and radiation therapy; In vivo electroporation; Malignant glioma; Radiation inducible gene therapy

Indexed keywords

DISEASES; DRUG THERAPY; FLUORESCENCE; GENETIC ENGINEERING; TUMORS;

CASPASE-8 GENE THERAPY; COMBINED GENE AND RADIATION THERAPY; IN VIVO ELECTROPORATION; MALIGNANT GLIOMA; RADIATION-INDUCIBLE GENE THERAPY;

BRAIN;

CASPASE 8; COMPLEMENTARY DNA; EARLY GROWTH RESPONSE FACTOR 1; GREEN FLUORESCENT PROTEIN; LUCIFERASE; PLASMID VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER GENE THERAPY; CANCER RADIOTHERAPY; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG EFFECT; ELECTROPORATION; ENZYME ACTIVATION; GENETIC TRANSFECTION; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RADIATION DOSE; TREATMENT RESPONSE; TUMOR VOLUME;

ANIMALS; APOPTOSIS; BRAIN NEOPLASMS; CASPASE 8; COMBINED MODALITY THERAPY; EARLY GROWTH RESPONSE PROTEIN 1; ELECTROPORATION; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GENETIC VECTORS; GLIOMA; HUMANS; LUCIFERASES; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; PLASMIDS; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 43049178167     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2008.02.002     Document Type: Article

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