Evidence for calreticulin attenuation of cardiac hypertrophy induced by pressure overload and soluble agonists

American Journal of Pathology

Volumn 176, Issue 3, 2010, Pages 1113-1121

  Papp, Sylvia ^a   Dziak, Ewa ^a   Kabir, Golam ^b   Backx, Peter ^b   Clement, Sophie ^c   Opas, Michal ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CALRETICULIN; ENDOTHELIN 1; PHENYLEPHRINE;

ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; CONTROLLED STUDY; EMBRYONIC STEM CELL; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; MALE; MOUSE; NONHUMAN; NULL CELL; ONCOGENE SRC; PRIORITY JOURNAL;

EID: 77749279475     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2010.090392     Document Type: Article

References (32)

1. Nakamura K, Robertson M, Liu G, Dickie P, Nakamura K, Guo JQ, Duff HJ, Opas M, Kavanagh K, Michalak M: Complete heart block and sudden death in mice overexpressing calreticulin. J Clin Invest 2001, 107:1245-1253
2. Hattori K, Nakamura K, Hisatomi Y, Matsumoto S, Suzuki M, Harvey RP, Kurihara H, Hattori S, Yamamoto T, Michalak M, Endo F: Arrhythmia induced by spatiotemporal overexpression of calreticulin in the heart. Mol Genet Metab 2007, 91:285-293
3. Hunter JJ, Chien KR: Signaling pathways for cardiac hypertrophy and failure. N Engl J Med 1999, 341:1276-1283
4. Ghatpande S, Goswami S, Mascareno E, Siddiqui MA: Signal transduction and transcriptional adaptation in embryonic heart development and during myocardial hypertrophy. Mol Cell Biochem 1999, 196:93-97
5. Taigen T, De Windt LJ, Lim HW, Molkentin JD: Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy. Proc Natl Acad Sci USA 2000, 97:1196-1201
6. Kuppuswamy D, Kerr C, Narishige T, Kasi VS, Menick DR, Cooper G: Association of tyrosine-phosphorylated c-Src with the cytoskeleton of hypertrophying myocardium. J Biol Chem 1997, 272:4500-4508
7. Kovacic B, Ilic D, Damsky CH, Gardner DG: c-Src activation plays a role in endothelin-dependent hypertrophy of the cardiac myocyte. J Biol Chem 1998, 273:35185-35193
8. Laser M, Willey CD, Jiang WJ, Cooper G, Menick DR, Zile MR, Kuppuswamy D: Integrin activation and focal complex formation in cardiac hypertrophy. J Biol Chem 2000, 275:35624-35630
9. Torsoni AS, Constancio SS, Nadruz W Jr, Hanks SK, Franchini KG: Focal adhesion kinase is activated and mediates the early hypertrophic response to stretch in cardiac myocytes. Circ Res 2003, 93:140-147
10. Tsutsui H, Ishibashi Y, Imanaka-Yoshida K, Yamamoto S, Yoshida T, Sugimachi M, Urabe Y, Takeshita A: Alterations in sarcoplasmic reticulum calcium-storing proteins in pressure-overload cardiac hypertrophy. Am J Physiol Heart Circ Physiol 1997, 272:H168-H175
11. Sato Y, Ferguson DG, Sako H, Dorn GW2, Kadambi VJ, Yatani A, Hoit BD, Walsh RA, Kranias EG: Cardiac-specific overexpression of mouse cardiac calsequestrin is associated with depressed cardiovascular function and hypertrophy in transgenic mice. J Biol Chem 1998, 273:28470-28477
12. Borlak J, Thum T: Hallmarks of ion channel gene expression in end-stage heart failure. FASEB J 2003, 17:1592-1608
13. Li J, Puceat M, Perez-Terzic C, Mery A, Nakamura K, Michalak M, Krause KH, Jaconi ME: Calreticulin reveals a critical Ca2+ checkpoint in cardiac myofibrillogenesis. J Cell Biol 2002, 158:103-113
14. Hescheler J, Fleischmann BK, Lentini S, Maltsev VA, Rohwedel J, Wobus AM, Addicks K: Embryonic stem cells: a model to study structural and functional properties in cardiomyogenesis. Cardiovasc Res 1997, 36:149-162
15. Nichols J, Evans, Evans EP, Smith AG: Establishment of germ-line-competent embryonic stem (ES) cells using differentiation inhibiting activity. Development 1990, 110:1341-1348
16. 2+ influx. J Biol Chem 1996, 271: 9332-9339
17. Bonnelye E, Merdad L, Kung V, Aubin JE: The orphan nuclear estrogen receptor-related receptor alpha (ERRalpha) is expressed throughout osteoblast differentiation and regulates bone formation in vitro. J Cell Biol 2001, 153:971-984
18. Cuspidi C, Ciulla M, Zanchetti A: Hypertensive myocardial fibrosis. Nephrol Dial Transplant 2006, 21:20-23
19. Peng X, Kraus MS, Wei H, Shen TL, Pariaut R, Alcaraz A, Ji G, Cheng L, Yang Q, Kotlikoff MI, Chen J, Chien K, Gu H, Guan JL: Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice. J Clin Invest 2006, 116: 217-227
20. Clement S, Stouffs M, Bettiol E, Kampf S, Krause KH, Chaponnier C, Jaconi M: Expression and function of alpha-smooth muscle actin during embryonic-stem-cell-derived cardiomyocyte differentiation. J Cell Sci 2007, 120:229-238
21. Papp S, Szabo E, Kim H, McCulloch CA, Opas M: Kinase-dependent adhesion to fibronectin: regulation by calreticulin. Exp Cell Res 2008, 314:1313-1326
22. Papp S, Fadel MP, Kim H, McCulloch CA, Opas M: Calreticulin affects fibronectin-based cell-substratum adhesion via the regulation of c-src activity. J Biol Chem 2007, 282:16585-16598
23. Sicheri F, Kuriyan J: Structures of Src-family tyrosine kinases. Curr Opin Struct Biol 1997, 7:777-785
24. Shu L, Shayman JA: Src kinase mediates the regulation of phospholipase C-gamma activity by glycosphingolipids. J Biol Chem 2003, 278:31419-31425
25. Heineke J, Molkentin JD: Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat Rev Mol Cell Biol 2006, 7:589-600
26. Mesaeli N, Nakamura K, Zvaritch E, Dickie P, Dziak E, Krause KH, Opas M, MacLennan DH, Michalak M: Calreticulin is essential for cardiac development. J Cell Biol 1999, 144:857-868
27. Michalak M, Groenendyk J, Szabo E, Gold LI, Opas M: Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum. Biochem J 2009, 417:651-666
28. Sugden PH: An overview of endothelin signaling in the cardiac myocyte. J Mol Cell Cardiol 2003, 35:871-886
29. Simonson MS, Wang Y, Herman WH: Nuclear signaling by endothelin-1 requires Src protein-tyrosine kinases. J Biol Chem 1996, 271:77-82
30. Herman WH, Simonson MS: Nuclear signaling by endothelin-1: a Ras pathway for activation of the c-fos serum response element. J Biol Chem 1995, 270:11654-11661
31. Deng XF, Rokosh DG, Simpson PC: Autonomous and growth factorinduced hypertrophy in cultured neonatal mouse cardiac myocytes: comparison with rat. Circ Res 2000, 87:781-788
32. Karliner JS, Honbo N, Epstein CJ, Xian M, Lau YF, Gray MO: Neonatal mouse cardiac myocytes exhibit cardioprotection induced by hypoxic and pharmacologic preconditioning and by transgenic overexpression of human Cu/Zn superoxide dismutase. J Mol Cell Cardiol 2000, 32:1779-1786