Neonatal mouse cardiac myocytes exhibit cardioprotection induced by hypoxic and pharmacologic preconditioning and by transgenic overexpression of human Cu/Zn superoxide dismutase

Journal of Molecular and Cellular Cardiology

Volumn 32, Issue 10, 2000, Pages 1779-1786

  Karliner, Joel S ^a,b   Honbo, Norman ^a   Epstein, Charles J ^c   Xian, Meiwei ^a   Lau, Yun Fai Chris ^a   Gray, Mary O ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cardioprotection; Cell culture; Cu Zn superoxide dismutase; Hypoxia; Neonatal mouse cardiac myocytes; Protein kinase C; Transgenic mice; 1 Agonists

Indexed keywords

BROXURIDINE; COPPER ZINC SUPEROXIDE DISMUTASE; CYTARABINE; NORADRENALIN; PHENYLEPHRINE; PRAZOSIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL VIABILITY; FLOW CYTOMETRY; GENE DELETION; GENE OVEREXPRESSION; HEART CELL CULTURE; HEART CONTRACTION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEART VENTRICLE HYPERTROPHY; HETEROZYGOSITY; HOMOZYGOSITY; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SPECIES DIFFERENCE; TRANSGENE; TRANSGENIC MOUSE;

ANIMALIA; MURINAE; MUS MUSCULUS;

EID: 0033744508     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2000.1212     Document Type: Article

References (34)

1. The green fluorescent protein is an efficient biological marker for cardiac myocytes
2. Ventricular remodeling in a mouse model of myocardial infarction
3. Demonstration of an early and a late phase of ischemic preconditioning in mice
4. Long-term expression of protein kinase C in adult mouse hearts improves postischemic recovery
5. Targeted disruption of the mouse Sod I gene makes the hearts vulnerable to ischemic reperfusion injury
6. 1-adrenergic receptor-stimulated cardiac hypertrophy and signaling
7. Chronic hypoxia increases β-adrenergic receptor mRNA and density but not signaling in neonatal rat cardiac myocytes
8. A selective ε-protein kinase C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death
9. Expression and regulation of adhesion molecules in cardiac cells by cytokines: Response to acute hypoxia
10. Hypoxia differentially regulates stress proteins in cultured cardiomyocytes: Role of the p38 stress-activated kinase signaling cascade, and relation to cytoprotection
11. 2 toxicity
12. Role of gelsolin in the actin filament regulation of cardiac L-type calcium channels
13. In vivo protein transduction: Delivery of a biologically active protein into the mouse
14. Transgenic mice with increased Cu/Zn-superoxide dismutase activity: Animal model of dosage effects in Down syndrome
15. 1-adrenergic receptor interaction: Evidence for independent regulation of growth and beating
16. Angiotensin II stimulates cardiac myocyte hypertrophy via paracrine release of TGF-β1 and endothelin-1 from fibroblasts
17. 1-adrenergic response
18. Hypertrophic responses of cultured neonatal mouse cardiac myocytes
19. 1- and β-adrenergic receptors in mouse cardiomyocytes
20. 1-adrenergic mechanism
21. 1(B)-adrenoceptors, pertussis toxin-sensitive G proteins, and protein kinase C
22. Alpha-1 adrenergic receptor agonist-induced preconditioning in isolated working rat hearts
23. Early and delayed preconditioning: Differential mechanisms and additive protection
24. 1-adrenoceptors
25. 2+ overload injury via protein kinase C signaling pathway
26. 1-adrenoceptors involves inhibition of apoptosis
27. Preconditioning of isolated rat heart is mediated by protein kinase C
28. Ischemic preconditioning induces selective translocation of protein kinase C isoforms epsilon and eta in the heart of conscious rabbits
29. Sustained in vivo cardiac protection by a rationally designed peptide that causes ε protein kinase C translocation
30. 1-Adrenergic stimulation induces cardiac tolerance to hypoxia via induction and activation of Mn-SOD
31. Recombinant adenovirus-mediated cardiac gene transfer of superoxide dismutase and catalase attenuates postischemic contractile dysfunction
32. Extracellular superoxide dismutase transgene overexpression preserves postischemic myocardial function in isolated murine hearts
33. Overexpression of CuZn-superoxide dismutase reduces hippocampal injury after global ischemia in transgenic mice
34. Overexpression of human copper, zinc-superoxide dismutase (SOD1) prevents postischemic injury