Yeast cell ultrastructure after amiodarone treatment

Tsitologiya

Volumn 51, Issue 11, 2009, Pages 911-916

  Ojovan, S M ^a   Knorre, D A ^a   Severin, F F ^a   Bakeeva, L E ^a  

^a MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

Amiodarone; Apoptosis; Cell ultrastructure; Lipid particles (lp); Phospholipidosis; Yeast saccharomyces cerevisiae

Indexed keywords

AMIODARONE; ANTIARRHYTHMIC AGENT; MITOCHONDRIAL PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; YSP2 PROTEIN, S CEREVISIAE;

APOPTOSIS; ARTICLE; DRUG EFFECT; ELECTRON MICROSCOPY; GENETICS; MUTATION; SACCHAROMYCES CEREVISIAE; ULTRASTRUCTURE;

AMIODARONE; ANTI-ARRHYTHMIA AGENTS; APOPTOSIS; MICROSCOPY, ELECTRON; MITOCHONDRIAL PROTEINS; MUTATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 77749264946     PISSN: 00413771     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Achleitner G, Gaigg B., Krasser A., Kainersdorfer E., Kohlwein S.D., Perktold A., Zellnig G., Daum G. 1999. Association between the endoplasmic reticulum and mitochondria of yeast facilitates interorganelle transport of phospholipids through membrane contact. Eur. J. Biochem. 264 : 545-553.
2. Athenstaedt K., Daum G. 1997. Biosynthesis of phosphatidic acid in lipid particles and endoplasmic reticulum of Saccharomyces cerevisiae. J. Bacteriol. 179 : 7611-7616.
3. Bolt M. W., Card J. W., Racz W. J., Brien J. F., Massey T. E. 2001. Disruption of mitochondrial function and cellular ATP levels by amiodarone and N-desethylamiodarone in initiation of amiodarone-induced pulmonary cytotoxicity. J. Pharmacol. Exp. Ther. 298 : 1280-1289.
4. Brasaemle D. L. 2007. Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis. J. Lipid. Res. 48 : 2547-2559.
5. Campbell C. L. Tanaka N. White K. H., Thorsness P. E. 1994. Mitochondrial morphological and functional defects in yeast caused by yme 1 are suppressed by mutation of a 26S protease subunit homologue. Mol. Biol. Cell. 5 : 899-905.
6. Dake M. D., Madison J. M., Montgomery C. K., Shellito J. E., Hinchcliffe W. A., Winkler M. L., Bainton D. F. 1985. Electron microscopic demonstration of lysosomal inclusion bodies in lung liver, lymph nodes, and blood leukocytes of patients with amiodarone pulmonary toxicity. Amer. J. Med. 78 : 506-512.
7. De la Iglesia F. A., Feuer G., McGuire E. J., Takada A. 1975. Morphological and biochemical changes in the liver of various species in experimental phospholipidosis after diethylaminoethoxyhexestrol treatment. Toxicol. Appl. Pharmacol. 34 : 28-44.
8. Fromenty B., Fisch C., Berson A., Letteron P., Larrey D., Pessayre D. 1990. Dual effect of amiodarone on mitochondrial respiration. Initial protonophoric uncoupling effect followed by inhibition of the respiratory chain at the levels of complex I and complex II. J. Pharmacol. Exp. Ther. 255 : 1377-1384.
9. Gaigg B., Simbeni R., Hrastnik C., Paltauf F., Daum G. 1995. Characterization of a microsomal subfraction associated with mitochondria of the yeast, Saccharomyces cerevisiae. Involvement in synthesis and import of phospholipids into mitochondria. Biochim. biophys. acta. 1234 : 214-220.
10. Gross S. A., Somani P. 1986. Amiodarone-induced ultrastructural changes in canine myocardial fibers. Amer. Heart. J. 112 : 771-779.
11. Gupta S. S., Ton V. K., Beaudry V., Rulli S., Cunningham K., Rao R. 2003. Antifungal activity of amiodarone is mediated by disruption of calcium homeostasis. J. Biol. Chem. 278 : 28 831-28 839.
12. Heger J. J., Prystowsky E. N., Jackman W. M., NaccarelIi G. V., Warfel K. A., Rinkenberger R. L., Zipes D. P. 1981. Clinical efficacy and electrophysiology during long-term therapy for recurrent ventricular tachycardia or ventricular fibrillation. N. Engl. J. Med. 305 : 539-545.
13. Kannan R., Sarma J. S., Guha M., Venkataraman K. 1989. Tissue drug accumulation and ultrastructural changes during amiodarone administration in rats. Fundam. Appl. Toxicol. 13 : 793-803.
14. Knorre D. A., Ojovan S. M., Saprunova V. B., Sokolov S. S., Bakeeva L. E., Severin F. F. 2008. Mitochondrial matrix fragmentation as a protection mechanism of yeast Saccharomyces cerevisiae. Biochemistry (Mosc). 73 : 1254-1259.
15. Leber R., Zinser E., Zellnig G., Paltauf F., Daum G. 1994. Characterization of lipid particles of the yeast, Saccharomyces cerevisiae. Yeast. 10: 1421-1428.
16. Martin W. J., Kachel D. L., Vilen T., Natarajan V. 1989. Mechanism of phospholipidosis in amiodarone pulmonary toxicity. J. Pharmacol. Exp. Ther. 251 : 272-278.
17. Perktold A., Zechmann B., Daum G., Zellnig G. 2007. Organelle association visualized by three-dimensional ultrastructural imaging of the yeast cell. FEMS Yeast Res. 7 : 629-638. (Pubitemid 46788682)
18. Pirovino M., Muller O., Zysset T., Honegger U. 1988. Amiodarone-induced hepatic phospholipidosis: correlation of morphological and biochemical findings in an animal model. Hepatology. 8 : 591-598. (Pubitemid 18173767)
19. Pozniakovsky A. I., Knorre D. A., Markova O. V., Hyman A. A., Skulachev V. P., Severin F. F. 2005. Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeast. J. Cell. Biol. 168 : 257-269.
20. Reynolds E. S. 1963. The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. J. Cell Biol. 17 : 208-2S13.
21. Sherman F. 2002. Getting started with yeast. Methods Enzymol. 350 : 3-41.
22. Singh B. N. 1996. Antiarrhythmic actions of amiodarone: a profile of a paradoxical agent. Amer. J. Cardiol. 78 : 41-53.
23. Somani P., Bandyopadhyay S., Gross S. A., Morady F., Dicarlo L. A. 1987. Amiodarone and multilamellar inclusion bodies. Br. J. Clin. Pharmacol. 24 : 237-239.
24. Yang H., Ren Q., Zhang Z. 2006. Chromosome or chromatin condensation leads to meiosis or apoptosis in stationary yeast (Saccharomyces cerevisiae) cells. FEMS Yeast Res. 6: 1254-1263.
25. Yasuda S. U., Sausville E. A., Hutchins J. B., Kennedy T., Woosley R. L. 1996. Amiodarone-induced lymphocyte toxicity and mitochondrial function. J. Cardiovasc. Pharmacol. 28 : 94-100.
26. Zhang Y. Q., Rao R. 2007. Global disruption of cell cycle progression and nutrient response by the antifungal agent amiodarone. J. Biol. Chem. 282 : 37 844-37 853.