Leptin and ghrelin concentrations and weight loss in Parkinson's disease

Acta Neurologica Scandinavica

Volumn 121, Issue 4, 2010, Pages 230-236

  Fiszer, U ^a   Michalowska M ^a   Baranowska, B ^a   Wolinska Witort E ^a   Jeske, W ^a   Jethon, M ^a   Piascik Gromada M ^a   Marcinowska Suchowierska, E ^a  

^a MEDICAL CENTER FOR POSTGRADUATE EDUCATION   (Poland)

Author keywords

Ghrelin; Leptin; Parkinson's disease; Weight loss

Indexed keywords

GHRELIN; GROWTH HORMONE; LEPTIN; LIOTHYRONINE; SOMATOMEDIN C; THYROTROPIN; THYROXINE;

ADIPOSE TISSUE; ADULT; APPETITE; ARTICLE; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; ENERGY BALANCE; FEMALE; HORMONE BLOOD LEVEL; HUMAN; MALE; MINI MENTAL STATE EXAMINATION; MONTGOMERY ASBERG DEPRESSION RATING SCALE; PARKINSON DISEASE; RATING SCALE; UNIFIED PARKINSON DISEASE RATING SCALE; WEIGHT REDUCTION;

ADIPOSE TISSUE; AGED; APPETITE; BODY MASS INDEX; ENERGY METABOLISM; FEMALE; GHRELIN; GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; LEPTIN; MALE; MIDDLE AGED; PARKINSON DISEASE; THYROID HORMONES; THYROTROPIN; WEIGHT LOSS;

EID: 77749258420     PISSN: 00016314     EISSN: 16000404     Source Type: Journal    
DOI: 10.1111/j.1600-0404.2009.01185.x     Document Type: Article

References (29)

1. Toth MJ, Fishman PS, Poehlman ET. Free-living daily energy expenditure in patient with Parkinson's disease. Neurology 1997 48 : 88 91.
2. Abbott RA, Cox M, Markus H et al. Diet, body and size and micronutrient status in Parkinson's disease. Eur J Clin Nutr 1992 55 : 701 707.
3. Beyer PL, Polarino MY, Michalek D et al. Weight change and body composition in patients with Parkinson's disease. J Am Diet Assoc 1995 95 : 979 983.
4. Lamberts SWJ. The endocrinology of aging and the brain. Arch Neurol 2002 59 : 1709 1711.
5. Baranowska B, Wasilewska-Dziubińska E, Radzikowska M et al. Neuropeptide Y, galanin and leptin release in obese women and in women with anorexia nervosa. Metabolism 1997 46 : 1384 1389.
6. Shioda S, Funahashi H, Nakajo S et al. Immunohistochemical localization of leptin receptor in the rat. Neurosci Lett 1998 243 : 41 4.
7. Evidente VG, Caviness JN, Adler CH et al. Serum leptin concentration and satiety in Parkinson's disease patients with and without weight loss. Mov Disord 2001 16 : 924 927.
8. Marzullo P, Verti B, Savia G et al. The relationship between active ghrelin levels and human obesity involves alterations in resting energy expenditure. J Clin Endocrinol Metab 2004 89 : 936 939.
9. Meier U, Gressner AM. Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin and resistin. Clin Chem 2004 50 : 1511 1525.
10. Kojima M, Hosoda H, Date Y et al. Ghrelin is a growth hormone releasing acylated peptide from stomach. Nature 1999 402 : 656 660.
11. Grinspoon S, Miller KK, Herzog DB et al. Effects of estrogen and recombinant human insulin-like growth factor-I on ghrelin secretion in severe undernutrition. J Clin Endocrinol Metab 2004 89 : 3988 3993.
12. Cusimano G, Capriani C, Bonifati V, Meco G. Hypothalamo-pituitary function and dopamine dependence in untreated parkinsonian patients. Acta Neurol Scand 1991 83 : 145 150.
13. Corcuff JB, Krim E, Tison F et al. Subthalamic nucleus stimulation in patients with Parkinson's disease does not increase serum ghrelin levels. Br J Nutr 2006 95 : 1028 1029.
14. Oertel WH, Quinn NP. Parkinsonism. Movement disorders. Neurological disorders: course and treatment. American Press 1996 64 : 715 772.
15. Bik W, Baranowska-Bik A, Wolińska-Witort E, Chmielowska M, Martyńska L, Baranowska B. The relationship between metabolic status and levels of adiponectin and ghrelin in lean women with polycystic ovary syndrome. Gynecol Endocrinol 2007 23 : 325 331.
16. Ostlund RE, Yang JW, Klein S, Gingerich R. Relation between plasma leptin concentration and body fat, gender, diet and metabolic covariates. J Clin Endocrinol Metab 1996 81 : 3909 3913.
17. Baranowska A, Bik W, Baranowska-Bik A et al. Neuroendocrine control of metabolic homeostasis in polish centenarians. J Physiol Pharmacol 2006 57 (Suppl. 6 55 61.
18. Russo VC, Metaxas S, Kobayashi K, Harris M, Werther GA. Antiapoptotic effects of leptin in human neuroblastoma cells. Endocrinology 2004 145 : 4103 4112.
19. Fujita Y, Murakami M, Ogawa Y et al. Leptin inhibits stress-induced apoptosis of T lymphocytes. Clin Exp Immunol 2002 128 : 21 6.
20. Cao G, Clark RS, Pei W et al. Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation. J Cereb Blood Flow Metab 2003 23 : 1137 1150.
21. Zhang F, Wang S, Signore AP, Chen J. Neuroprotective effects of leptin against ischemic injury induced by oxygen-glucose deprivation and transient cerebral ischemia. Stroke 2007 38 : 2329 2336.
22. Tsuboi Y, Uechara Y, Baba Y et al. Weight loss and adiponectin levels in patients with Parkinson's disease. Parkinson Relat Disord 2007 13 : S49.
23. Broglio F, Arvat E, Benso A et al. Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans. J Clin Endocrinol Metab 2001 86 : 5083 5086.
24. Nakazato M, Murakami N, Date Y et al. A role for ghrelin in the central regulation of feeding. Nature 2001 409 : 194 198.
25. Bachmann CG, Zapft A, Brunner E, Trenkwalder C. Dopaminergic treatment is associated with decreased body weight in patients with Parkinson's disease and dyskinesias. Eur J Neurol 2009 (In press).
26. Harvey J. Leptin: a multifaceted hormone in the central nervous system. Mol Neurobiol 2003 28 : 245 258.
27. Lu XY, Kim CS, Frazer A, Zhang W. Leptin: a potential novel antidepressant. PNAS 2006 103 : 1593 1598.
28. Himmerich H, Zimmermann P, Marcus I et al. Changes in the hypothalamic-pituitary-adrenal axis and leptin levels during antidepressant treatment. Neuropsychobiology 2007 55 : 28 35.
29. Durakoglugil M, Irving AJ, Harvey J. Leptin induces a novel form of NMDA receptor-dependent long-term depression. J Neurochem 2005 95 : 396 405.