Forebrain overexpression of CK1δ leads to down-regulation of dopamine receptors and altered locomotor activity reminiscent of ADHD

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 9, 2010, Pages 4401-4406

  Zhou, Mingming ^a   Rebholz, Heike ^a   Brocia, Christine ^a   Warner Schmidt, Jennifer L ^a   Fienberg, Allen A ^b   Nairn, Angus C ^c   Greengard, Paul ^a   Flajolet, Marc ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b Intra Cellular Therapies Inc   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CK1; D1R; Methylphenidate; Protein kinase amphetamine

Indexed keywords

CASEIN KINASE IDELTA; DEXAMPHETAMINE; DOPAMINE; DOPAMINE RECEPTOR; MESSENGER RNA; METHYLPHENIDATE; AMINO ACID RECEPTOR BLOCKING AGENT; AMPHETAMINE; DIZOCILPINE MALEATE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; ATTENTION DEFICIT DISORDER; BEHAVIOR DISORDER; CONTROLLED STUDY; DOWN REGULATION; DRUG RESPONSE; ENZYME ACTIVITY; FOREBRAIN; IN VIVO STUDY; INJECTION; LOCOMOTION; MOUSE; NESTING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYMPTOM; ANIMAL; ANIMAL BEHAVIOR; DRUG EFFECT; ENZYMOLOGY; METABOLISM;

MUS;

AMPHETAMINE; ANIMALS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BEHAVIOR, ANIMAL; CASEIN KINASE IDELTA; DIZOCILPINE MALEATE; DOWN-REGULATION; EXCITATORY AMINO ACID ANTAGONISTS; LOCOMOTION; METHYLPHENIDATE; MICE; PROSENCEPHALON; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2;

EID: 77749254848     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0915173107     Document Type: Article

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