Staphylococcal strains vary greatly in their ability to induce an inflammatory response in endothelial cells

Journal of Infectious Diseases

Volumn 201, Issue 6, 2010, Pages 871-880

  Grundmaiar, Matthias ^a   Tuchscherr, Lorena ^a   Brück, Michaela ^a   Viemann, Dorothee ^a   Roth, Johannes ^a   Willscher, Edith ^a   Becker, Karsten ^a   Peters, Georg ^a   Löffler, Bettina ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOXIN; PROTEINASE;

AGR GENE; ANIMAL CELL; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION; INFLAMMATION; INNATE IMMUNITY; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS INFECTION; UPREGULATION;

BACTERIAL PROTEINS; ENDOTHELIAL CELLS; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STAPHYLOCOCCUS AUREUS; TRANS-ACTIVATORS; UMBILICAL VEINS; VIRULENCE FACTORS;

EID: 77749243239     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/651023     Document Type: Article

References (32)

1. Lowy FD. Staphylococcus aureus infections. N Engl J Med 1998; 339: 520-532.
2. Gordon RJ, Lowy FD. Pathogenesis of methicillin-resistant Staphylococcus aureus infection. Clin Infect Dis 2008;46(suppl 5):S350-S359.
3. Petti CA, Fowler VG Jr. Staphylococcus aureus bacteremia and endocarditis. Infect Dis Clin North Am 2002; 16:413.
4. Remadi JP, Habib G, Nadji G, et al. Predictors of death and impact of surgery in Staphylococcus aureus infective endocarditis. Ann Thorac Surg 2007;83:1295-1302.
5. Tak T, Reed KD, Haselby RC, McCauley CS Jr, Shukla SK. An update on the epidemiology, pathogenesis and management of infective endocarditis with emphasis on Staphylococcus aureus. WMJ 2002; 101: 24-33.
6. Chavakis T, Wiechmann K, Preissner KT, Herrmann M. Staphylococcus aureus interactions with the endothelium: the role of bacterial "secretable expanded repertoire adhesive molecules" (SERAM) in disturbing host defense systems. Thromb Haemost 2005; 94:278-285.
7. Sinha B, Herrmann M. Mechanism and consequences of invasion of endothelial cells by Staphylococcus aureus. Thromb Haemost 2005; 94: 266-277.
8. Hauck CR, Ohlsen K. Sticky connections: extracellular matrix protein recognition and integrin-mediated cellular invasion by Staphylococcus aureus. Curr Opin Microbiol 2006;9:5-11.
9. Menzies BE. The role of fibronectin binding proteins in the pathogenesis of Staphylococcus aureus infections. Curr Opin Infect Dis 2003; 16:225-229.
10. Novick RP. Autoinduction and signal transduction in the regulation of staphylococcal virulence. Mol Microbiol 2003;48:1429-1449.
11. Yarwood JM, Schlievert PM. Quorum sensing in Staphylococcus infections. J Clin Invest 2003; 112:1620-1625.
12. Bhakdi S, Tranum-Jensen J. Alpha-toxin of Staphylococcus aureus. Microbiol Rev 1991;55:733-751.
13. Hildebrand A, Pohl M, Bhakdi S. Staphylococcus aureus alpha-toxin: dual mechanism of binding to target cells. J Biol Chem 1991; 266:17195-17200.
14. Haslinger-Loffler B, Kahl BC, Grundmeier M, et al. Multiple virulence factors are required for Staphylococcus aureus-induced apoptosis in endothelial cells. Cell Microbiol 2005;7:1087-1097.
15. Menzies BE, Kourteva I. Staphylococcus aureus alpha-toxin induces apoptosis in endothelial cells. FEMS Immunol Med Microbiol 2000; 29:39-45.
16. Springer TA. Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. Annu Rev Physiol 1995; 57:827-872.
17. Balwit JM, van Langevelde P, Vann JM, Proctor RA. Gentamicin-resistant menadione and hemin auxotrophic Staphylococcus aureus persist within cultured endothelial cells. J Infect Dis 1994; 170:1033-1037.
18. Sinha B, Francois PP, Nusse O, et al. Fibronectin-binding protein acts as Staphylococcus aureus invasin via fibronectin bridging to integrin alpha5betal. Cell Microbiol 1999; 1:101-117.
19. Juuti KM, Sinha B, Werbick C, Peters G, Kuusela PI. Reduced adherence and host cell invasion by methicillin-resistant Staphylococcus aureus expressing the surface protein PIs. J Infect Dis 2004; 189:1574-1584.
20. Haslinger-Löffler B, Bruck M, Grundmeier M, Peters G, Sinha B. Staphylococcal infections impair the mesothelial fibrinolytic system: the role of cell death and cytokine release. Thromb Haemost 2007; 98:813-822.
21. Strindhall J, Lindgren PE, Lofgren S, Kihlstrom E. Variations among clinical isolates of Staphylococcus aureus to induce expression of E-selectin and ICAM-1 in human endothelial cells. FEMS Immunol Med Microbiol 2002;32:227-235.
22. Tekstra J, Beekhuizen H, Van De Gevel JS, et al. Infection of human endothelial cells with Staphylococcus aureus induces the production of monocyte chemotactic protein-1 (MCP-1) and monocyte Chemotaxis. Clin Exp Immunol 1999; 117:489-495.
23. Matussek A, Strindhall J, Stark L, et al. Infection of human endothelial cells with Staphylococcus aureus induces transcription of genes encoding an innate immunity response. Scand J Immunol 2005;61:536-544.
24. Gomez MI, Lee A, Reddy B, et al. Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1. Nat Med 2004; 10:842-848.
25. Mattsson E, Heying R, Van De Gevel JS, Hartung T, Beekhuizen H. Staphylococcal peptidoglycan initiates an inflammatory response and procoagulant activity in human vascular endothelial cells: a comparison with highly purified lipoteichoic acid and TSST-1. FEMS Immunol Med Microbiol 2008;52:110-117.
26. Proctor RA, von EQ Kahl BC, et al. Small colony variants: a pathogenic form of bacteria that facilitates persistent and recurrent infections. Nat Rev Microbiol 2006;4:295-305.
27. Seggewiss J, Becker K, Kotte O, et al. Reporter metabolite analysis of transcriptional profiles of a Staphylococcus aureus strain with normal phenotype and its isogenic hemB mutant displaying the small colony variant phenotype. J Bacteriol 2006; 188:7765-7777.
28. Shopsin B, Drlica-Wagner A, Mathema B, Adhikari RP, Kreiswirth BN, Novick RP. Prevalence of agr dysfunction among colonizing Staphylococcus aureus strains. J Infect Dis 2008; 198:1171-1174.
29. von Eiff C, Becker K, Machka K, Stammer H, Peters G. Nasal carriage as a source of Staphylococcus aureus bacteremia. N Engl J Med 2001; 344: 11-16.
30. Traber KE, Lee E, Benson S, et al. agr function in clinical Staphylococcus aureus isolates. Microbiology 2008; 154:2265-2274.
31. Schnaith A, Kashkar H, Leggio SA, Addicks K, Kronke M, Krut O. Staphylococcus aureus subvert autophagy for induction of caspase-in-dependent host cell death. J Biol Chem 2007; 282:2695-2706.
32. Garzoni C, Kelley WL. Staphylococcus aureus: new evidence for intracellular persistence. Trends Microbiol 2009; 17:59-65.