Staphylococcal infections impair the mesothelial fibrinolytic system: The role of cell death and cytokine release

Thrombosis and Haemostasis

Volumn 98, Issue 4, 2007, Pages 813-822

  Haslinger Löffler, Bettina ^a   Brück, Michaela ^a   Grundmeier, Matthias ^a   Peters, Georg ^a   Sinha, Bhanu ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Bacterial peritonitis; Mesothelial fibrinolytic system; Peritoneal fibrosis; Statins

Indexed keywords

CELL ADHESION MOLECULE; CHEMOKINE; CYTOKINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; SIMVASTATIN;

APOPTOSIS; ARTICLE; BACTERIAL PERITONITIS; BACTERIAL STRAIN; BACTERIUM CULTURE; CELL ACTIVATION; CONTROLLED STUDY; FIBRINOLYSIS; HEMOLYSIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; INFLAMMATION; MESOTHELIUM CELL; MONONUCLEAR CELL; NONHUMAN; PERITONEUM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; SUPERNATANT;

CELL ADHESION; CELL DEATH; CYTOKINES; EPITHELIUM; FIBRINOLYSIS; FIBROSIS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; IMMUNE SYSTEM; INFLAMMATION; LEUKOCYTES, MONONUCLEAR; PERITONEUM; SPECIES SPECIFICITY; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TIME FACTORS;

EID: 35048854038     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH07-01-0003     Document Type: Article

References (48)

1. Lowy FD. Staphylococcus aureus infections. N Engl J Med 1998; 339: 520-532.
2. Novick R. Pathogenicity Factors and Their Regulation, In: Gram-Positive Pathogens, Washington, D.C., American Society of Microbiology, 2000: 392-407.
3. Berger D, Buttenschoen K. Management of abdominal sepsis. Langenbecks Arch Surg 1998; 383: 35-43.
4. Farthmann EH, Schoffel U. Epidemiology and pathophysiology of intraabdominal infections (IAI). Infection 1998; 26: 329-334.
5. Fried L, Piraino B. Peritonitis. In: Textbook of Peritoneal Dialysis, Kluwer Academic Publishers, 2000: 545-564.
6. Coles GA, Williams JD, Topley N. Peritoneal inflammation and long-term changes in peritoneal structure and function. In: Textbook of Peritoneal Dialysis, 2nd ed., KluwerAcademic Publishers, 2000:565-583.
7. Menzies D. Postoperative adhesions: their treatment and relevance in clinical practice. Ann R Coll Surg Engl 1993; 75: 147-153.
8. van Hinsbergh VW, Kooistra T, Scheffer MA, et al. Characterization and fibrinolytic properties of human omental tissue mesothelial cells. Comparison with endothelial cells. Blood 1990; 75: 1490-1497.
9. Goedde M, Sitter T, Schiffl H, et al. Coagulation-and fibrinolysis-related antigens in plasma and dialysate of CAPD patients. Perit Dial Int 1997; 17: 162-166.
10. Sitter T, Spannagl M, Schiffl H, et al. Imbalance between intraperitoneal coagulation and fibrinolysis during peritonitis of CAPD patients: the role of mesothelial cells. Nephrol Dial Transplant 1995; 10: 677-683.
11. Hellebrekers BW, Emeis JJ, Kooistra T, et al. A role for the fibrinolytic system in postsurgical adhesion formation. Fertil Steril 2005; 83: 122-129.
12. Dobbie JW, Jasani MK. Role of imbalance of intracavity fibrin formation and removal in the pathogenesis of peritoneal lesions in CAPD. Perit Dial Int 1997; 17: 121-124.
13. Hausmann MJ, Rogachev B, Weiler M, et al. Accessory role of human peritoneal mesothelial cells in antigen presentation and T-cell growth. Kidney Int 2000; 57: 476-486.
14. Li FK, Davenport A, Robson RL, et al. Leukocyte migration across human peritoneal mesothelial cells is dependent on directed chemokine secretion and ICAM-1 expression. Kidney Int 1998; 54: 2170-2183.
15. Yao V, Platell C, Hall JC. Role of peritoneal mesothelial cells in peritonitis. Br J Surg 2003; 90: 1187-1194.
16. Tekstra J, Visser CE, Tuk CW, et al. Identification of the major chemokines that regulate cell influxes in peritoneal dialysis patients. J Am Soc Nephrol 1996; 7: 2379-2384.
17. Jonjic N, Peri G, Bernasconi S, et al. Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells. J Exp Med 1992; 176: 1165-1174.
18. Visser CE, Steenbergen JJ, Betjes MG, et al. Interleukin-8 production by human mesothelial cells after direct stimulation with staphylococci. Infect Immun 1995; 63: 4206-4209.
19. Visser CE, Tekstra J, Brouwer-Steenbergen JJ, et al. Chemokines produced by mesothelial cells: huGRO-alpha, IP-10, MCP-1 and RANTES. Clin Exp Immunol 998; 112: 270-275.
20. Fried L, Abidi S, Bernardini J, et al. Hospitalization in peritoneal dialysis patients. Am J Kidney Dis 1999; 33: 927-933.
21. Krishnan M, Thodis E, Ikonomopoulos D, et al. Predictors of outcome following bacterial peritonitis in peritoneal dialysis. Pent Dial Int 2002; 22: 573-581.
22. Tranaeus A, Heimburger O, Lindholm B. Peritonitis in continuous ambulatory peritoneal dialysis (CAPD): diagnostic findings, therapeutic outcome and complications. Perit Dial Int 1989; 9: 179-190.
23. Haslinger B, Strangfeld K, Peters G, et al. Staphylococcus aureus alpha-toxin induces apoptosis in peripheral blood mononuclear cells: role of endogenous tumour necrosis factor-alpha and the mitochondrial death pathway. Cell Microbiol 2003; 5: 729-741.
24. Jeyaseelan S. Activation induced by pore-forming bacterial toxins. Trends Microbiol 2001; 9: 416-417.
25. Jonas D, Walev I, Berger T, et al. Novel path to apoptosis: small transmembrane pores created by staphylococcal alpha-toxin in T lymphocytes evoke internucleosomal DNA degradation. Infect Immun 1994; 62: 1304-1312.
26. Haagen IA, Heezius HC, Verkooyen RP, et al. Adherence of peritonitis-causing staphylococci to human peritoneal mesothelial cell monolayers. J Infect Dis 1990; 161: 266-273.
27. Haslinger-Löffler B, Wagner B, Brück M, et al. Staphylococcus aureus induces caspase-independent cell death in human peritoneal mesothelial cells. Kidney Int 2006; 70: 1089-1098.
28. Sinha B, Francois PP, Nüsse O, et al. Fibronectin-binding protein acts as Staphylococcus aureus invasin via fibronectin bridging to integrin alpha5beta1. Cell Microbiol 1999; 1: 101-117.
29. 2 synthesis in human peritoneal mesothelial cells: role of hyperosmolarity. J Am Soc Nephrol 1998; 9: 2005-2012.
30. Proctor RA, Christman G, Mosher DF. Fibronectin-induced agglutination of Staphylococcus aureus correlates with invasivencss. J Lab Clin Med 1984; 104: 455-469.
31. Enright MC, Robinson DA, Randle G, et al. The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA). Proc Natl Acad Sci USA 2002; 99: 7687-7692.
32. Juuti KM, Sinha B, Werbick C, et al. Reduced adherence and host cell invasion by methicillin-resistant Staphylococcus aureus expressing the surface protein Pls. J Infect Dis 2004; 189: 1574-1584.
33. Sinha B, Francois P, Que YA, et al. Heterologously expressed Staphylococcus aureus fibronectin-binding proteins are sufficient for invasion of host cells. Infect Immun 2000; 68: 6871-6878.
34. Strindhall J, Lindgren PE, Lofgren S, et al. Variations among clinical isolates of Staphylococcus aureus to induce expression of E-selectin and ICAM-1 in human endothelial cells. FEMS Immunol Med Microbiol 2002; 32: 227-235.
35. Sitter T, Toet K, Fricke H, et al. Modulation of procoagulant and fibrinolytic system components of mesothelial cells by inflammatory mediators. Am J Physiol 1996; 271: 1256-1263.
36. Brauner A, Hylander B, Wretlind B. Interleukin-6 and interleukin-8 in dialysate and serum from patients on continuous ambulatory peritoneal dialysis. Am J Kidney Dis 1993; 22: 430-435.
37. Haslinger B, Goedde MF, Toet KH, et al. Simvastatin increases fibrinolytic activity in human peritoneal mesothelial cells independent of cholesterol lowering. Kidney Int 2002; 62: 1611-1619.
38. Haslinger B, Kleemann R, Toet KH, et al. Simvastatin suppresses tissue factor expression and increases fibrinolytic activity in tumor necrosis factor-alpha-activated human peritoneal mesothelial cells. Kidney Int 2003; 63: 2065-2074.
39. Mandl-Weber S, Cohen CD, Haslinger B, et al. Vascular endothelial growth factor production and regulation in human peritoneal mesothelial cells. Kidney Int 2002; 61: 570-578.
40. Marshall BC, Santana A, Xu QP, et al. Metalloproteinases and tissue inhibitor of metalloproteinases in mesothelial cells. Cellular differentiation influences expression. J Clin Invest 1993; 91: 1792-1799.
41. Holmdahl L, Falkenberg M, Ivarsson ML, et al. Plasminogen activators and inhibitors in peritoneal tissue. APMIS 1997; 105: 25-30.
42. Holmdahl L. The role of fibrinolysis in adhesion formation. Eur J Surg 1997; Suppl: 24-31.
43. Ivarsson ML, Holmdahl L, Falk P, et al. Characterization and fibrinolytic properties of mesothelial cells isolated from peritorical lavage. Scand J Clin Lab Invest 1998; 58: 195-203.
44. Mandl-Weber S, Haslinger B, Lederer SR, et al. Heat-killed microorganisms induce PAI-1 expression in human peritoneal mesothelial cells: role of interleukin-1alpha. Am J Kidney Dis 2001; 37: 815-819.
45. Dobbie JW. Pathogenesis of peritoneal fibrosing syndromes (sclerosing peritonitis) in peritoneal dialysis. Perit Dial Int 1992; 12: 14-27.
46. Vipond MN, Whawell SA, Thompson JN, et al. Effect of experimental peritonitis and ischaemia on peritoneal fibrinolytic activity. Eur J Surg 1994; 160: 471-477.
47. Heilmann C, Gerke C, Perdreau-Remington F. et al. Characterization of Tn917 insertion mutants of Staphylococcus epidermidis affected in biofilm formation. Infect Immun 1996; 64: 277-282.
48. Novick R. Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus. Virology 1967; 33: 155-166.