Metalation of pyridines with nbuli-li-aminoalkoxide mixed aggregates: The origin of chemoselectivity

Journal of the American Chemical Society

Volumn 132, Issue 7, 2010, Pages 2410-2416

  Khartabil, Hassan K ^a   Gros, Philippe C ^a   Fort, Yves ^a   Ruiz López, Manuel F ^a  

^a NANCY UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2-CHLOROPYRIDINE; AGGREGATE TYPE; ALKYLLITHIUMS; B3LYP/6-31G; CHEMICAL SPECIES; CHEMO-SELECTIVITY; COORDINATING SOLVENTS; DIMER CONCENTRATIONS; GASPHASE; LITHIATION; METALATIONS; MIXED AGGREGATES; NUCLEOPHILIC ADDITIONS; PYRIDINE DERIVATIVES; REACTIVE AGGREGATE; RELATIVE REACTION RATES; SOLVENT EFFECTS; TEMPERATURE EFFECTS; TETRAMERS; THEORETICAL CALCULATIONS; THEORETICAL STUDY; TRANSITION STRUCTURES;

ACTIVATION ENERGY; ADDITION REACTIONS; AGGREGATES; ALKALINITY; CONTRAST MEDIA; DENSITY FUNCTIONAL THEORY; DIMERS; HEXANE; LITHIUM; PYRIDINE; REACTION RATES; STOICHIOMETRY;

ORGANIC SOLVENTS;

2 CHLOROPYRIDINE; DIMER; HEXANE; LITHIUM DERIVATIVE; N METHYL 2 PYRROLIDINYLMETHOXIDE; NUCLEOPHILE; PYRIDINE DERIVATIVE; SOLVENT; TETRAMER; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CONCENTRATION (PARAMETERS); DENSITY FUNCTIONAL THEORY; ENANTIOSELECTIVITY; ENERGY; GAS; QUALITATIVE ANALYSIS; STOICHIOMETRY; TEMPERATURE SENSITIVITY;

EID: 77749240213     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja910350q     Document Type: Article

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