Sp1 binds to the G allele of the1087 polymorphism in the IL-10 promoter and promotes IL-10 mRNA transcription and protein production

Genes and Immunity

Volumn 11, Issue 2, 2010, Pages 181-187

  Larsson, L ^a   Rymo, L ^b   Berglundh, T ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

B cells; Cytokines; Transcription factors

Indexed keywords

ADENINE; GUANINE; INTERLEUKIN 10; MESSENGER RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PU 1; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SPI B; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA POLYMORPHISM; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENOTYPE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING;

ALLELES; B-LYMPHOCYTES; GENOTYPE; HUMANS; INTERLEUKIN-10; LIPOPOLYSACCHARIDES; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINS; PROTO-ONCOGENE PROTEINS; REGULATORY SEQUENCES, NUCLEIC ACID; RNA, MESSENGER; SP1 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

EID: 77649342998     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2009.103     Document Type: Article

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