Stabilizing Biomacromolecules in Nontoxic Nano-Structured Materials

JALA - Journal of the Association for Laboratory Automation

Volumn 15, Issue 2, 2010, Pages 136-144

  Domach, Michael M ^a   Walker, Lynn M ^a  

^a CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

antibodies; block copolymers; hydrogels; protein aggregation; protein stability

Indexed keywords

BIOMACROMOLECULES; COST-EFFECTIVE METHODS; NANO-STRUCTURED; NANOSTRUCTURED HYDROGELS; PROTEIN AGGREGATION; PROTEIN STABILITY; PROTEIN STABILIZATION;

BLOCK COPOLYMERS; COPOLYMERIZATION; HYDROGELS;

ANTIBODIES;

IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN FC FRAGMENT; MACROGOL; MONOCLONAL ANTIBODY; NANOMATERIAL; POLOXAMER; SUCROSE; TREHALOSE;

AFFINITY CHROMATOGRAPHY; AMINO ACID SEQUENCE; BIOTECHNOLOGY; CONTROLLED STUDY; FLOW KINETICS; FREEZE DRYING; GENETIC ENGINEERING; HYDROGEL; HYDROPHOBICITY; MACROMOLECULE; METABOLIC ENGINEERING; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN STABILITY; PROTEIN SYNTHESIS; REVIEW; THERMODYNAMICS;

EID: 77649306835     PISSN: 15355535     EISSN: 15402452     Source Type: Journal    
DOI: 10.1016/j.jala.2010.01.002     Document Type: Review

References (50)

1. Addressing stability of biological drugs. Genetic Engineering & Biotechnology News - Biotechnology from Bench to Business 2005, 25(6) http://www.genengnews.com/articles/chitem.aspx?aid=949&chid=943%920(941%920of%209)948/913/2009%2202:2022:2051%2020PM (accessed December 2009).
2. Kennedy C., Zanapolidou R., Sagar S., Tristram-Nagle S., and Domach M. Microcalorimetry, fractionation, and fluorescence study of yeast alcohol dehydrogenase: structure and heterogeneity implications. Biotechnol. Prog 5 (1989) 164-169
3. Zanapalidou H., and Domach M. Effect of self-association on the transport of a-chymotrypsin across microporous membranes. Biotechnol. Prog 7 (1991) 335-342
4. Chatelier R.C. Indefinite isoenthalpic self-association of solute molecules. Biophys. Chem 28 (1987) 121-128
5. Bishop, S. Aggregation of monoclonal antibodies. In Workshop on Protein Aggregation. Edited by. Brekenridge, CO; 2006.
6. Andya J.D., Hsu C.C., and Shire S.J. Mechanisms of aggregate formation and carbohydrate excipient stabilization of lyophilized humanized monoclonal antibody formulations. AAPS PharmSci 5 2 (2003) Article 10
7. Bismuto E., and Irace G. The effect of molecular confinement on the conformational dynamics of the native and partly folded state of apomyoglobin. FEBS Lett 509 (2001) 476-480
8. Eggers D.K., and Valentine J.S. Molecular confinement influences protein structure and enhances thermal protein stability. Protein Sci 10 (2001) 250-261
9. Gill I., and Ballesteros A. Bioencapsulation within synthetic polymers (Part 1): sol-gel encapsulated biologicals. Trends Biotechnol 18 (2000) 282-296
10. Jin W., and Brennan J.D. Properties and applications of proteins encapsulated within sol-gel derived materials. Anal. Chim. Acta 461 (2002) 1-36
11. Menaa B., Herrero M., Rives V., Lavrenko M., and Eggers D.K. Favourable influence of hydrophobic surfaces on protein structure in porous organically-modified silica glasses. Biomaterials 29 (2008) 2710-2718
12. Pioselli B., Bettati S., Demidkina T.V., Zakomirdina L.N., Phillips R.S., and Mozzarelli A. Tyrosine phenol-lyase and tryptophan indole-lyase encapsulated in wet nanoporous silica gels: Selective stabilization of tertiary conformations. Protein Sci 13 (2004) 913-924
13. Cheung M.S., Klimov D., and Thirumalai D. Molecular crowding enhances native state stability and refolding rates of globular proteins. Proc. Natl. Acad. Sci. U.S.A 102 (2005) 4753-4758
14. McPhie P., Ni Y.-S., and Minton A.P. Macromolecular crowding stabilizes the molten globule form of apomyoglobin with respect to both cold and heat unfolding. J. Mol. Biol 361 (2006) 7-10
15. Michael P., Loren S., and Pernilla W.-S. Macromolecular crowding increases structural content of folded proteins. FEBS Lett 581 (2007) 5065-5069
16. Minton A.P. The influence of macromolecular crowding and macromolecular confinement on biochemical reactions in physiological media. J. Biol. Chem 276 (2001) 10577-10580
17. Minton A.P. Macromolecular crowding. Curr. Biol 16 (2006) R269-R271
18. Stagg L., Zhang S.-Q., Cheung M.S., and Wittung-Stafshede P. Molecular crowding enhances native structure and stability of {alpha}/ protein flavodoxin. Proc. Natl. Acad. Sci. U.S.A 104 (2007) 18976-18981
19. Ping G., Yang G., and Yuan J.-M. Depletion force from macromolecular crowding enhances mechanical stability of protein molecules. Polymer 47 (2006) 2564-2570
20. Ping G., Yuan J.M., Sun Z., and Wei Y. Studies of effects of macromolecular crowding and confinement on protein folding and protein stability. J. Mol. Recognit 17 (2004) 433-440
21. Timasheff S.N. The control of protein stability and association by weak interactions with water: How do solvents affect these processes?. Annu. Rev. Biophys. Biomol. Struct 22 (1993) 67-97
22. Chennamsetty N., Voynov V., Kayser V., Helk B., and Trout B.L. Design of therapeutic proteins with enhanced stability. Proc. Natl. Acad. Sci. U.S.A 106 (2009) 11937-11942
23. Ellis R.J. Macromolecular crowding: Obvious but underappreciated. Trends Biochem. Sci 26 (2001) 597-604
24. Pozzo D.C., Hollabaugh K.R., and Walker L.M. Rheology and phase behavior of copolymer-templated nanocomposite materials. Journal of Rheology 49 (2005) 759-782
25. Pozzo D.C., and Walker L.M. Three-dimensional nanoparticle arrays templated by self-assembled block-copolymer gels. Macromolecular Symposia 227 (2005) 203-210
26. Pozzo D.C., and Walker L.M. Shear orientation of nanoparticle arrays templated in a thermoreversible block copolymer micellar crystal. Macromolecules 40 (2007) 5801-5811
27. Pozzo D.C., and Walker L.M. Small-angle neutron scattering of silica nanoparticles templated in PEO-PPO-PEO cubic crystals. Colloids Surf. A Physicochem. Eng. Asp 294 (2007) 117-129
28. Pozzo D.C., and Walker L.M. Macroscopic shear alignment of linear nanoparticle arrays in soft crystals of cylindrical polymer micelles. Eur. Phys. J. E Soft Matter 26 (2008) 183-189
29. Mortensen K., Almdal K., Schwahn D., and Bates F.S. Small-angle neutron scattering studies of the phase behavior and mesophases of homopolymers, block copolymers and complex mixtures. J. Appl. Crystallogr 30 (1997) 702-707
30. Alexandridis P. Poly(ethylene oxide) poly(propylene oxide) block copolymer surfactants. Curr. Opin. Colloid Interface Sci 2 (1997) 478-489
31. Wanka G., Hoffmann H., and Ulbricht W. Phase diagrams and aggregation behavior of poly(oxyethylene)-poly(oxypropylene)-poly(oxyethylene) triblock copolymers in aqueous solutions. Macromolecules 27 (1994) 4145-4159
32. Guo L., Colby R.H., Lin M.Y., and Dado G.P. Micellar structure changes in aqueous mixtures of nonionic surfactants. Journal of Rheology 45 (2001) 1223-1243
33. Eiser E., Molino F., Forte G., and Pithon X. Flow in micellar cubic crystals. Rheologica Acta 39 (2000) 201-208
34. Mortensen K. Structural studies of aqueous solutions of PEO-PPO-PEO triblock copolymers, their micellar aggregates and mesophases: A small-angle neutron scattering study. J. Phys. Condens. Matter 8 (1996) A103-A124
35. Hamley I.W. Amphiphilic diblock copolymer gels: the relationship between structure and theology. Philos. Transact. A Math. Phys. Eng. Sci 359 (2001) 1017-1044
36. Prudhomme R.K., Wu G.W., and Schneider D.K. Structure and rheology studies of poly(oxyethylene-oxypropylene-oxyethylene) aqueous solution. Langmuir 12 (1996) 4651-4659
37. Wu C.H., Liu T.B., Chu B.J., Schneider D.K., and Graziano V. Characterization of the PEO-PPO-PEO triblock copolymer and its application as a separation medium in capillary electrophoresis. Macromolecules 30 (1997) 4574-4583
38. Forster S., and Antonietti M. Amphiphilic block copolymers in structure-controlled nanomaterial hybrids. Advanced Materials 10 (1998) 195
39. Yang P.D., Zhao D.Y., Margolese D.I., Chmelka B.F., and Stucky G.D. Generalized syntheses of large-pore mesoporous metal oxides with semicrystalline frameworks. Nature 396 (1998) 152-155
40. Alexandridis P., and Hatton T.A. Poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block-copolymer surfactants in aqueous-solutions and at interfaces-thermodynamics, structure, dynamics, and modeling. Colloids Surf. A Physicochem. Eng. Asp 96 (1995) 1-46
41. Cottin X., and Monson P.A. Substitutionally ordered solid-solutions of hard-spheres. J. Chem. Phys 102 (1995) 3354-3360
42. Trizac E., Eldridge M.D., and Madden P.A. Stability of the AB crystal for asymmetric binary hard sphere mixtures. Mol. Phys 90 (1997) 675-678
43. Hunt N., Jardine R., and Bartlett P. Superlattice formation in mixtures of hard-sphere colloids. Phys. Rev. E Stat. Phys. Plasmids Fluids Relat. Interdiscip. Topics 62 (2000) 900-913
44. Saunders A.E., and Korgel B.A. Observation of an AB phase in bidisperse nanocrystal superlattices. Chemphyschem 6 (2005) 61-65
45. Yardimci H., Chung B., Harden J.L., and Leheny R.L. Phase behavior and local dynamics of concentrated triblock copolymer micelles. J. Chem. Phys 123 (2005) 244908
46. Pozzo D.C. Templating Nanoparticles Using Thermo-Reversible Soft Crystals Ph.D. Dissertation (2006), Carnegie Mellon University, Pittsburgh PA
47. Malmsten M., Linse P., and Cosgrove T. Adsorption of PEO PPO PEO block copolymers at silica. Macromolecules 25 (1992) 2474-2481
48. Shar J.A., Obey T.M., and Cosgrove T. Adsorption studies of polyethers-Part II: adsorption onto hydrophilic surfaces. Colloids Surf. A Physicochem. Eng. Asp 150 (1999) 15-23
49. Ng C.L., Lee H.K., and Li S.F.Y. Prevention of protein adsorption on surfaces by polyethylene oxide-polypropylene oxide-polyethylene oxide triblock copolymers in capillary electrophoresis. J. Chromatogr. A 659 (1994) 427-434
50. Nobbman U., Connah M., et al. Dynamic light scattering as a relative tool for assessing the molecular integrity and stability of monoclonal antibodies. Biotechnol. Genet. Eng. Rev 24 (2007) 117-128