Protective effect of resin adsorption on septic plasma-induced tubular injury

Critical Care

Volumn 14, Issue 1, 2010, Pages

  Cantaluppi, Vincenzo ^a   Weber, Viktoria ^b   Lauritano, Carola ^a   Figliolini, Federico ^a   Beltramo, Silvia ^a   Biancone, Luigi ^a   De Cal, Massimo ^c   Cruz, Dinna ^c   Ronco, Claudio ^c   Segoloni, Giuseppe P ^a   Tetta, Ciro ^d   Camussi, Giovanni ^a,e  

^a UNIVERSITY OF TURIN   (Italy)

^b DANUBE UNIVERSITY KREMS   (Austria)

^c SAN BORTOLO HOSPITAL   (Italy)

^d FRESENIUS MEDICAL CARE   (Germany)

^e MOLINETTE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CD40 ANTIGEN; FAS ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; PROTEIN ZO1; RESIN; SODIUM PROTON EXCHANGE PROTEIN 3; AMBERCHROM CG161 M; AUTACOID; CYTOKINE; POLYMER;

ADULT; APOPTOSIS; ARTICLE; CELL ADHESION; CELL POLARITY; CELL STRUCTURE; CLINICAL ARTICLE; DOWN REGULATION; FEMALE; GRANULOCYTE; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY EPITHELIUM; KIDNEY INJURY; MALE; PRIORITY JOURNAL; SEPSIS; ADSORPTION; AGED; BLOOD; CELL CULTURE; ISOLATION AND PURIFICATION; KIDNEY DISEASE; KIDNEY PROXIMAL TUBULE; MIDDLE AGED; PATHOLOGY;

ADSORPTION; AGED; CELLS, CULTURED; CYTOKINES; FEMALE; HUMANS; INFLAMMATION MEDIATORS; KIDNEY DISEASES; KIDNEY TUBULES, PROXIMAL; MALE; MIDDLE AGED; POLYMERS; SEPSIS;

EID: 77649288355     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc8835     Document Type: Article

References (60)

1. Cruz DN, Ronco C. Acute kidney injury in the intensive care unit: current trends in incidence and outcome. Crit Care 2007, 11:149. 2206527, 17666115, 10.1186/cc5965.
2. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P. Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 2004, 8:R204-R212. 522841, 15312219, 10.1186/cc2872.
3. Schrier RW, Wang W. Acute renal failure and sepsis. N Engl J Med 2004, 351:159-169. 10.1056/NEJMra032401, 15247356.
4. Lopez JA, Jorge S, Resina C, Santos C, Pereira A, Neves J, Antunes F, Prata MM. Prognostic utility of RIFLE for acute renal failure in patients with sepsis. Crit Care 2007, 11:408. 2206455, 17430577, 10.1186/cc5722.
5. Wan L, Bellomo R, Di Giantomasso D, Ronco C. The pathogenesis of septic acute renal failure. Curr Opin Crit Care 2003, 9:496-502. 10.1097/00075198-200312000-00006, 14639069.
6. Klenzak J, Himmelfarb J. Sepsis and the kidney. Crit Care Clin 2005, 21:211-222. 10.1016/j.ccc.2005.01.002, 15781158.
7. Mariano F, Cantaluppi V, Stella M, Romanazzi GM, Assenzio B, Cairo M, Biancone L, Triolo G, Ranieri VM, Camussi G. Circulating plasma factors induce tubular and glomerular alterations in septic burns patients. Crit Care 2008, 12:R42. 2447585, 18364044, 10.1186/cc6848.
8. Jo SK, Cha DR, Cho WY, Kim HK, Chang KH, Yun SY, Won NH. Inflammatory cytokines and lipopolysaccharide induce Fas-mediated apoptosis in renal tubular cells. Nephron 2002, 91:406-415. 10.1159/000064280, 12119470.
9. Guo R, Wang Y, Minto AW, Quigg RJ, Cunningham PN. Acute renal failure in endotoxemia is dependent on caspase activation. J Am Soc Nephrol 2004, 15:3093-3102. 10.1097/01.ASN.0000145530.73247.F5, 15579512.
10. Cunningham PN, Dyanov HM, Park P, Wang J, Newell KA, Quigg RJ. Acute renal failure in endotoxemia is caused by TNF acting directly on TNF receptor-1 in kidney. J Immunol 2002, 168:5817-5823.
11. Schmidt C, Höcherl K, Schweda F, Kurtz A, Bucher M. Regulation of renal sodium transporters during severe inflammation. J Am Soc Nephrol 2007, 18:1072-1083. 10.1681/ASN.2006050454, 17314327.
12. Schmidt C, Höcherl K, Bucher M. Cytokine-mediated regulation of urea transporters during experimental endotoxemia. Am J Physiol Renal Physiol 2007, 292:F1479-F1489. 10.1152/ajprenal.00460.2006, 17229673.
13. Schmidt C, Höcherl K, Bucher M. Regulation of renal glucose transporters during severe inflammation. Am J Physiol Renal Physiol 2007, 292:F804-F811. 10.1152/ajprenal.00258.2006, 17032938.
14. Mariano F, Tetta C, Guida G, Triolo G, Camussi G. Hemofiltration reduces the serum priming activity on neutrophil chemiluminescence in septic patients. Kidney Int 2001, 60:1598-1605. 10.1046/j.1523-1755.2001.00974.x, 11576379.
15. Sander A, Armbruster W, Sander B, Daul AE, Lange R, Peters J. Haemofiltration increases IL-6 clearance in early systemic inflammatory response syndrome but does not alter IL-6 and TNF alpha plasma concentrations. Intensive Care Med 1997, 23:878-884. 10.1007/s001340050425, 9310806.
16. De Vriese AS, Colardyn FA, Philippé JJ, Vanholder RC, De Sutter JH, Lameire NH. Cytokine removal during continuous hemofiltration in septic patients. J Am Soc Nephrol 1999, 10:846-853.
17. Kellum JA, Johnson JP, Kramer D, Palevsky P, Brady JJ, Pinsky MR. Diffusive vs. convective therapy: effects on mediators of inflammation in patients with severe systemic inflammatory response syndrome. Crit Care Med 1998, 26:1995-2000. 10.1097/00003246-199812000-00027, 9875910.
18. Cruz D, Bellomo R, Kellum JA, de Cal M, Ronco C. The future of extracorporeal support. Crit Care Med 2008, 36:S243-S252. 10.1097/CCM.0b013e318168e4f6, 18382201.
19. Kellum JA, Song M, Venkataraman R. Hemoadsorption removes tumor necrosis factor, interleukin-6, and interleukin-10, reduces nuclear factor-kappaB DNA binding, and improves short-term survival in lethal endotoxemia. Crit Care Med 2004, 32:801-805. 10.1097/01.CCM.0000114997.39857.69, 15090965.
20. Tetta C, Cavaillon JM, Schulze M, Ronco C, Ghezzi PM, Camussi G, Serra AM, Curti F, Lonnemann G. Removal of cytokines and activated complement components in an experimental model of continuous plasma filtration coupled with sorbent adsorption. Nephrol Dial Transplant 1998, 13:1458-1464. 10.1093/ndt/13.6.1458, 9641176.
21. American College of Chest Physicians Society of Critical Care Medicine Consensus Conference Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992, 20:864-875. American College of Chest Physicians Society of Critical Care Medicine Consensus Conference.
22. Hoste EA, Kellum JA. Rifle criteria provide robust assessment of kidney dysfunction and correlate with hospital mortality. Crit Care Med 2006, 34:2016-2017. 10.1097/01.CCM.0000219374.43963.B5, 16801870.
23. Bellomo R, Kellum JA, Ronco C. Defining and classifying acute renal failure: from advocacy to consensus and validation of the RIFLE criteria. Intensive Care Med 2007, 33:409-413. 10.1007/s00134-006-0478-x, 17165018.
24. Cantaluppi V, Biancone L, Romanazzi GM, Figliolini F, Beltramo S, Galimi F, Camboni MG, Deriu E, Conaldi P, Bottelli A, Orlandi V, Herrera MB, Pacitti A, Segoloni GP, Camussi G. Macrophage stimulating protein may promote tubular regeneration after acute injury. J Am Soc Nephrol 2008, 19:1904-1918. 2551565, 18614774, 10.1681/ASN.2007111209.
25. Conaldi PG, Biancone L, Bottelli A, Wade-Evans A, Racusen LC, Boccellino M, Orlandi V, Serra C, Camussi G, Toniolo A. HIV-1 kills renal tubular epithelial cells in vitro by triggering an apoptotic pathway involving caspase activation and Fas upregulation. J Clin Invest 1998, 102:2041-2049. 509158, 9854039, 10.1172/JCI3480.
26. Deregibus MC, Cantaluppi V, Calogero R, Lo Iacono M, Tetta C, Biancone L, Bruno S, Bussolati B, Camussi G. Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA. Blood 2007, 110:2440-2448. 10.1182/blood-2007-03-078709, 17536014.
27. Montrucchio G, Lupia E, De Martino A, Silvestro L, Savu SR, Cacace G, De Filippi PG, Emanuelli G, Camussi G. Plasmin promotes an endothelium-dependent adhesion of neutrophils. Involvement of platelet activating factor and P-selectin. Circulation 1996, 93:2152-2160.
28. Bijuklic K, Sturn DH, Jennings P, Kountchev J, Pfaller W, Wiedermann CJ, Patsch JR, Joannidis M. Mechanisms of neutrophil transmigration across renal proximal tubular HK-2 cells. Cell Physiol Biochem 2006, 17:233-244. 10.1159/000094128, 16790999.
29. Camussi G, Biancone L, Iorio EL, Silvestro L, Da Col R, Capasso C, Rossano F, Servillo L, Balestrieri C, Tufano MA. Porins and lypopolysaccharide stimulate platelet activating factor synthesis by human mesangial cells. Kidney Int 1992, 42:1309-1318. 10.1038/ki.1992.422, 1335527.
30. Ronco C, Tetta C, Mariano F, Wratten ML, Bonello M, Bordoni V, Cardona X, Inguaggiato P, Pilotto L, d'Intini V, Bellomo R. Interpreting the mechanisms of continuous renal replacement therapy in sepsis: the peak concentration hypothesis. Artif Organs 2003, 27:792-801. 10.1046/j.1525-1594.2003.07289.x, 12940901.
31. Simmons EM, Himmelfarb J, Sezer MT, Chertow GM, Mehta RL, Paganini EP, Soroko S, Freedman S, Becker K, Spratt D, Shyr Y, Ikizler TA. Plasma cytokine levels predict mortality in patients with acute renal failure. Kidney Int 2004, 65:1357-1365. 10.1111/j.1523-1755.2004.00512.x, 15086475.
32. Tetta C, Gianotti L, Cavaillon JM, Wratten ML, Fini M, Braga M, Bisagni P, Giavaresi G, Bolzani R, Giardino R. Coupled plasma filtration adsorption in a rabbit model of endotoxic shock. Crit Care Med 2000, 28:1526-1533. 10.1097/00003246-200005000-00045, 10834707.
33. Ronco C, Brendolan A, Lonnemann G, Bellomo R, Piccinni P, Digito A, Dan M, Irone M, La Greca G, Inguaggiato P, Maggiore U, De Nitti C, Wratten ML, Ricci Z, Tetta C. A pilot study of coupled plasma filtration with adsorption in septic shock. Crit Care Med 2002, 30:1250-1255. 10.1097/00003246-200206000-00015, 12072677.
34. Mizuno S, Nakamura T. Prevention of neutrophil extravasation by Hepatocyte Growth Factor leads to attenuations of tubular apoptosis and renal dysfunction in mouse ischemic kidneys. Am J Pathol 2005, 166:1895-1905. 1602426, 15920173.
35. Cunningham PN, Wang Y, Guo R, He G, Quigg RJ. Role of Toll-like receptor 4 in endotoxin-induced acute renal failure. J Immunol 2004, 172:2629-2635.
36. van Griensven M, Probst C, Müller K, Hoevel P, Pape HC. Leukocyte-endothelial interaction via ICAM-1 are detrimental in polymicrobial sepsis. Shock 2006, 25:254-259. 10.1097/01.shk.0000196497.49683.13, 16552357.
37. Wu X, Guo R, Wang Y, Cunningham PN. The role of ICAM-1 in endotoxin-induced acute renal failure. Am J Physiol Renal Physiol 2007, 293:F1262-F1271. 10.1152/ajprenal.00445.2006, 17670897.
38. Gold JA, Parsey M, Hoshino Y, Hoshino S, Nolan A, Yee H, Tse DB, Weiden MD. CD40 contributes to lethality in acute sepsis: in vivo role for CD40 in innate immunity. Infect Immun 2003, 71:3521-3528. 155725, 12761137, 10.1128/IAI.71.6.3521-3528.2003.
39. Pontrelli P, Ursi M, Ranieri E, Capobianco C, Schena FP, Gesualdo L, Grandaliano G. CD40L proinflammatory and profibrotic effects on proximal tubular epithelial cells: role of NF-kappaB and lyn. J Am Soc Nephrol 2006, 17:627-636. 10.1681/ASN.2005020202, 16452499.
40. Castellano G, Cappiello V, Fiore N, Pontrelli P, Gesualdo L, Schena FP, Montinaro V. CD40 ligand increases complement C3 secretion by proximal tubular epithelial cells. J Am Soc Nephrol 2005, 16:2003-2011. 10.1681/ASN.2002120972, 15872081.
41. Inwald DP, Faust SN, Lister P, Peters MJ, Levin M, Heyderman R, Klein NJ. Platelet and soluble CD40L in meningococcal sepsis. Intensive Care Med 2006, 32:1432-1437. 10.1007/s00134-006-0250-2, 16810523.
42. van Kooten C, Woltman AM, Daha MR. Immunological function of tubular epithelial cells: the functional implications of CD40 expression. Exp Nephrol 2000, 8:203-207. 10.1159/000020669, 10940717.
43. Hotchkiss RS, Nicholson DW. Apoptosis and caspases regulate death and inflammation in sepsis. Nat Rev Immunol 2006, 6:813-822. 10.1038/nri1943, 17039247.
44. Zanotti-Cavazzoni SL, Hollenberg SM. Cardiac dysfunction in severe sepsis and septic shock. Curr Opin Crit Care 2009, 15:392-397. 10.1097/MCC.0b013e3283307a4e, 19633546.
45. Stromberg PE, Woolsey CA, Clark AT, Clark JA, Turnbull IR, McConnell KW, Chang KC, Chung CS, Ayala A, Buchman TG, Hotchkiss RS, Coopersmith CM. CD4+ lymphocytes control gut epithelial apoptosis and mediate survival in sepsis. FASEB J 2009, 23:1817-1825. 10.1096/fj.08-119024, 19158156.
46. Langenberg C, Bagshaw SM, May CN, Bellomo R. The histopathology of septic acute kidney injury: a systematic review. Crit Care 2008, 12:R38. 2447560, 18325092, 10.1186/cc6823.
47. Lameire N. The pathophysiology of acute renal failure. Crit Care Clin 2005, 21:197-210. 10.1016/j.ccc.2005.01.001, 15781157.
48. Glynne PA, Evans TJ. Inflammatory cytokines induce apoptotic and necrotic cell shedding from human proximal tubular epithelial cell monolayers. Kidney Int 1999, 55:2573-2597. 10.1046/j.1523-1755.1999.00456.x, 10354308.
49. Glynne PA, Picot J, Evans TJ. Coexpressed nitric oxide synthase and apical beta (1) integrins influence tubule cell adhesion after cytokine-induced injury. J Am Soc Nephrol 2001, 12:2370-2383.
50. Bonventre JV, Weinberg JM. Recent advances in the pathophysiology of ischemic acute renal failure. J Am Soc Nephrol 2003, 14:2199-2210. 10.1097/01.ASN.0000079785.13922.F6, 12874476.
51. Zegers MM, O'Brien LE, Yu W, Datta A, Mostov KE. Epithelial polarity and tubulogenesis in vitro. Trends Cell Biol 2003, 13:169-176. 10.1016/S0962-8924(03)00036-9, 12667754.
52. Fink MP, Delude RL. Epithelial barrier dysfunction: A unifying theme to explain the pathogenesis of multiple organ dysfunction at the cellular level. Crit Care Clin 2005, 21:177-196. 10.1016/j.ccc.2005.01.005, 15781156.
53. Lee DB, Huang E, Ward HJ. Tight junction biology and kidney dysfunction. Am J Physiol Renal Physiol 2006, 290:F20-F34. 10.1152/ajprenal.00052.2005, 16339962.
54. Han X, Fink MP, Delude RL. Proinflammatory cytokines cause NO-dependent and -independent changes in expression and localization of tight junction proteins in intestinal epithelial cells. Shock 2003, 19:229-237. 10.1097/00024382-200303000-00006, 12630522.
55. Han X, Fink MP, Uchiyama T, Yang R, Delude RL. Increased iNOS activity is essential for pulmonary epithelial tight junction dysfunction in endotoxemic mice. Am J Physiol Lung Cell Mol Physiol 2004, 286:L259-L267. 10.1152/ajplung.00187.2003, 12896879.
56. Han X, Fink MP, Uchiyama T, Yang R, Delude RL. Increased iNOS activity is essential for hepatic epithelial tight junction dysfunction in endotoxemic mice. Am J Physiol Gastrointest Liver Physiol 2004, 286:G126-G136. 10.1152/ajpgi.00231.2003, 12946943.
57. Yew WS, Pal SK. Correlation of microalbuminuria and outcome in patients with extensive burns. Br J Anaesth 2006, 97:499-502. 10.1093/bja/ael211, 16885170.
58. Molnár Z, Szakmány T, Heigl P. Microalbuminuria does not reflect increased systemic capillary permeability in septic shock. Intensive Care Med 2003, 29:391-395. 10.1007/s00134-003-1818-8, 12560870.
59. Christensen EI, Birn H. Megalin and cubilin: synergistic endocytic receptors in renal proximal tubule. Am J Physiol Renal Physiol 2001, 280:F562-F573.
60. Leheste JR, Rolinski B, Vorum H, Hilpert J, Nykjaer A, Jacobsen C, Aucouturier P, Moskaug JO, Otto A, Christensen EI, Willnow TE. Megalin knockout mice as an animal model of low molecular weight proteinuria. Am J Pathol 1999, 155:1361-1370. 1867027, 10514418.