The pathophysiology of acute renal failure

Critical Care Clinics

Volumn 21, Issue 2, 2005, Pages 197-210

  Lameire, Norbert ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ANGIOTENSIN; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; CHEMOKINE; CISPLATIN; CYTOKINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIN 1; LEUKOTRIENE C4; LEUKOTRIENE D4; N(G) NITROARGININE; N6 (1 IMINOETHYL)LYSINE; NITRIC OXIDE SYNTHASE INHIBITOR; NONSTEROID ANTIINFLAMMATORY AGENT; OXYGENASE INHIBITOR; POTASSIUM SPARING DIURETIC AGENT; PROSTAGLANDIN H2; RECREATIONAL DRUG; THROMBOXANE A2; VASOCONSTRICTOR AGENT;

ACUTE KIDNEY FAILURE; ACUTE KIDNEY TUBULE NECROSIS; APOPTOSIS; AUTOREGULATION; CELL DEATH; DISEASE SEVERITY; ENDOTHELIUM CELL; HEART INFARCTION PREVENTION; HEMODYNAMICS; HUMAN; HYPERKALEMIA; INFLAMMATION; INFLAMMATORY CELL; KIDNEY BLOOD FLOW; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY ISCHEMIA; METABOLIC ACIDOSIS; NEPHROTOXICITY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RENOVASCULAR DISEASE; REPERFUSION INJURY; REVIEW; SIDE EFFECT; TUBULAR DYSFUNCTION; UREMIA;

EID: 15244341319     PISSN: 07490704     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccc.2005.01.001     Document Type: Review

References (94)

1. N. Singri, S.N. Ahja, and M.L. Levin Acute renal failure JAMA 289 2003 747 751
2. J.A. Kellum, N. Levin, and C. Bouman Developing a consensus classification system for acute renal failure Curr Opin Crit Care 8 2002 509 514
3. R.L. Mehta, and G.M. Chertow Acute renal failure definitions and classification: time for change? J Am Soc Nephrol 14 2003 2178 2187
4. R. Bellomo, C. Ronco, and J.A. Kellum Acute renal failure-definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group Crit Care 8 2004 R204 R212
5. K. Nash, A. Hafeez, and S. Hou Hospital-acquired renal insufficiency Am J Kidney Dis 39 2002 930 936
6. R.C. Blantz Pathophysiology of pre-renal azotemia Kidney Int 53 1998 512 523
7. K.F. Badr, and I. Ichikawa Prerenal failure: a deleterious shift from renal compensation to decompensation N Engl J Med 319 1988 623 629
8. C. Baylis, and B.M. Brenner Modulation by prostaglandin synthesis inhibitors of the action of exogenous angiotensin II on glomerular ultrafiltration in the rat Circ Res 43 1978 889 898
9. V.J. Dzau, M. Packer, and L.S. Lilly Prostaglandins in severe congestive heart failure: relation to activation of the renin-angiotensin system and hyponatremia N Engl J Med 310 1984 347 352
10. L. De Nicola, R.C. Blantz, and F.B. Gabbai Nitric oxide and angiotensin II. Glomerular and tubular interaction in the rat J Clin Invest 89 1992 1248 1256
11. D.C. Brater Anti-inflammatory agents and renal function Semin Arthritis Rheum 32 3 Suppl 1 2002 33 42
12. G. Gambaro, and M.A. Perazella Adverse renal effects of anti-inflammatory agents: evaluation of selective and nonselective cyclooxygenase inhibitors J Intern Med 253 2003 643 652
13. H. Schepkens, R. Vanholder, and J.M. Billiouw Life-threatening hyperkalemia during combined therapy with angiotensin-converting enzyme inhibitors and spironolactone: an analysis of 25 cases Am J Med 110 2001 438 441
14. D.N. Juurlink, M.M. Mamdani, and D.S. Lee Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study N Engl J Med 351 2004 543 551
15. P. MacDowall, P.A. Kalra, and D.J. O'Donoghue Risk of morbidity from renovascular disease in elderly patients with congestive cardiac failure Lancet 352 1998 13 16
16. S.S. Franklin, and R.D. Smith A comparison of enalapril plus hydrochlorothiazide with standard triple therapy in renovascular hypertension Nephron 44 Suppl 1 1986 73 82
17. R.S. Barsoum Tropical acute renal failure Contrib Nephrol 144 2004 44 52
18. M.S. Sever, E. Erek, and R. Vanholder Lessons learned from the catastrophic Marmara earthquake: factors influencing the final outcome of renal victims Clin Nephrol 61 2004 413 421
19. N. Lameire, R. Mehta, and R. Vanholder The organization and interventions of the ISN Renal Disaster Relief Task Force Adv Ren Replace Ther 10 2003 93 99
20. R.L. Mehta, M.T. Pascual, and S. Soroko Spectrum of acute renal failure in the intensive care unit: the PICARD experience Kidney Int 66 2004 1613 1621
21. F.G. Brivet, D.J. Kleinknecht, and P. Loirat Acute renal failure in intensive care units: causes, outcome, and prognostic factors of hospital mortality; a prospective, multicenter study. French Study Group on Acute Renal Failure [see comments] Crit Care Med 24 1996 192 198
22. L. Cole, R. Bellomo, and W. Silvester A prospective, multicenter study of the epidemiology, management, and outcome of severe acute renal failure in a "closed" ICU system Am J Respir Crit Care Med 162 2000 191 196
23. F. Liano, E. Junco, and J. Pascual The spectrum of acute renal failure in the intensive care unit compared with that seen in other settings. The Madrid Acute Renal Failure Study Group Kidney Int Suppl 66 1998 S16 S24
24. E.A. Hoste, N.H. Lameire, and R.C. Vanholder Acute renal failure in patients with sepsis in a surgical ICU: predictive factors, incidence, comorbidity, and outcome J Am Soc Nephrol 14 2003 1022 1030
25. R.W. Schrier, and W. Wang Acute renal failure and sepsis N Engl J Med 351 2004 159 169
26. D. Breen, and D. Bihari Acute renal failure as a part of multiple organ failure: the slippery slope of critical illness Kidney Int Suppl 66 1998 S25 S33
27. P. Carmichael, and A.R. Carmichael Acute renal failure in the surgical setting ANZ J Surg 73 2003 144 153
28. A. Deman, E. Hoste, and W. Van Biesen Insuffisance rénale aigue postopératoire: épidémiologie, causes, pronostic et traitement P. Lesavre T. Drueke C. Legendre Actualités néphrologiques Jean Hamburger 2004 Flammarion Paris 227 254
29. E.M. Levy, C.M. Viscoli, and R.I. Horwitz The effect of acute renal failure on mortality: a cohort analysis JAMA 275 1996 1489 1494
30. S.J. Gruber, and C.J. Shapiro Nephropathy induced by contrast medium N Engl J Med 348 2003 2257 2259
31. J.J. Dillon Nephrotoxicity from antibacterial, antifungal, and antiviral drugs B.A. Molitoris W.F. Finn Acute renal failure: a companion to Brenner & Rector's the kidney 2001 WB Saunders Philadelphia 349 364
32. M. Agraharkar, S.C. Guba, and R.L. Safirstein Acute renal failure associated with cancer chemotherapy B.A. Molitoris W.F. Finn Acute renal failure: a companion to Brenner & Rector's the kidney 2001 WB Saunders Philadelphia 365 375
33. F. Boccalandro, and H.V. Anderson Contrast-induced nephropathy: back to basics J Invasive Cardiol 15 2003 317 318
34. P. Evenepoel Acute toxic renal failure Best Pract Res Clin Anaesthesiol 18 2004 37 52
35. P.H. Bach Acute renal failure associated with occupational and environmental settings B.A. Molitoris W.F. Finn Acute renal failure: a companion to Brenner & Rector's the kidney 2001 WB Saunders Philadelphia 414 424
36. J.H. Turney Acute renal failure associated with recreational drug use B.A. Molitoris W.F. Finn Acute renal failure: a companion to Brenner & Rector's the kidney 2001 WB Saunders Philadelphia 397 405
37. G.P. Kaushal, D. Portilla, and E. Megyesi Cellular mechanisms of nephrotoxicity M.E. De Broe G.A. Porter W.M. Bennet Clinical nephrotoxins 2003 Kluwer Academic Publishers Dordrecht 65 76
38. R.S. Hotchkiss, and I.E. Karl The pathophysiology and treatment of sepsis N Engl J Med 348 2003 138 150
39. D.W. Landry, and J.A. Oliver The pathogenesis of vasodilatory shock N Engl J Med 345 2001 588 595
40. V. Kon, and K.F. Badr Biological actions and pathophysiologic significance of endothelin in the kidney Kidney Int 40 1991 1 12
41. J.G. Filep Role for endogenous endothelin in the regulation of plasma volume and albumin escape during endotoxin shock in conscious rats Br J Pharmacol 129 2000 975 983
42. K. Reinhart, O. Bayer, and F. Brunkhorst Markers of endothelial damage in organ dysfunction and sepsis Crit Care Med 30 2002 S302 S312
43. D. Schwartz, M. Mendonca, and I. Schwartz Inhibition of constitutive nitric oxide synthase (NOS) by nitric oxide generated by inducible NOS after lipopolysaccharide administration provokes renal dysfunction in rats J Clin Invest 100 1997 439 448
44. J.V. Bonventre, and J.M. Weinberg Recent advances in the pathophysiology of ischemic acute renal failure J Am Soc Nephrol 14 2003 2199 2210
45. N.H. Lameire, and R. Vanholder Pathophysiology of ischaemic acute renal failure Best Pract Res Clin Anaesthesiol 18 2004 21 36
46. B.A. Molitoris Transitioning to therapy in ischemic acute renal failure J Am Soc Nephrol 14 2003 265 267
47. B.A. Molitoris, and T.A. Sutton Endothelial injury and dysfunction: role in the extension phase of acute renal failure Kidney Int 66 2004 496 499
48. R.W. Schrier, W. Wang, and B. Poole Acute renal failure: definitions, diagnosis, pathogenesis, and therapy J Clin Invest 114 2004 5 14
49. W. Lieberthal, and S.K. Nigam Acute renal failure. II. Experimental models of acute renal failure: imperfect but indispensable Am J Physiol Renal Physiol 278 2000 F1 F12
50. S.N. Heyman, W. Lieberthal, and P. Rogiers Animal models of acute tubular necrosis Curr Opin Crit Care 8 2002 526 534
51. S. Rosen, and S.N. Heyman Difficulties in understanding human acute tubular necrosis: limited data and flawed animal models Kidney Int 60 2001 1220 1224
52. A. Bohle, J. Christensen, and F. Kokot Acute renal failure in man: new aspects concerning pathogenesis. A morphometric study Am J Nephrol 10 1990 374 388
53. L.C. Racusen The morphologic basis of acute renal failure B.A. Molitoris W.F. Finn Acute renal failure: a companion to Brenner & Rector's the kidney 2001 WB Saunders Philadelphia 1 12
54. R. Thadhani, M. Pascual, and J.V. Bonventre Acute renal failure N Engl J Med 334 1996 1448 1460
55. M. Brezis, and S. Rosen Hypoxia of the renal medulla: its implications for disease N Engl J Med 332 1995 647 655
56. N.K. Hollenberg, M. Epstein, and S.M. Rosen Acute oliguric renal failure in man: evidence for preferential renal cortical ischemia Medicine (Baltimore) 47 1968 455 474
57. N.K. Hollenberg, D.F. Adams, and D.E. Oken Acute renal failure due to nephrotoxins: renal hemodynamic and angiographic studies in man N Engl J Med 282 1970 1329 1334
58. F.C. Reubi The pathogenesis of anuria following shock Kidney Int 5 1974 106 110
59. J.D. Conger Vascular alterations in acute renal failure: roles in initiation and maintenance B.A. Molitoris W.F. Finn Acute renal failure: a companion to Brenner & Rector's the kidney 2001 WB Saunders Philadelphia 13 29
60. S.V. Brodsky, T. Yamamoto, and T. Tada Endothelial dysfunction in ischemic acute renal failure: rescue by transplanted endothelial cells Am J Physiol Renal Physiol 282 2002 F1140 F1149
61. T.A. Sutton, C.J. Fisher, and B.A. Molitoris Microvascular endothelial injury and dysfunction during ischemic acute renal failure Kidney Int 62 2002 1539 1549
62. J.V. Bonventre, and A. Zuk Ischemic acute renal failure: an inflammatory disease? Kidney Int 66 2004 480 485
63. H. Rabb The T cell as a bridge between innate and adaptive immune systems: implications for the kidney Kidney Int 61 2002 1935 1946
64. H. Rabb, Z. Wang, and T. Nemoto Acute renal failure leads to dysregulation of lung salt and water channels Kidney Int 63 2003 600 606
65. A. Zuk, J.V. Bonventre, and K.S. Matlin Expression of fibronectin splice variants in the postischemic rat kidney Am J Physiol Renal Physiol 280 2001 F1037 F1053
66. S.J. Atkinson, and B.A. Molitoris Cytoskeletal alterations as a basis of cellular injury in acute renal failure B.A. Molitoris W.F. Finn Acute renal failure: a companion to Brenner & Rector's the kidney 2001 WB Saunders Philadelphia 119 131
67. B.A. Molitoris Actin cytoskeleton in ischemic acute renal failure Kidney Int 66 2004 871 883
68. V.S. Alejandro, W.J. Nelson, and P. Huie Postischemic injury, delayed function and Na + /K(+)-ATPase distribution in the transplanted kidney Kidney Int 48 1995 1308 1315
69. M.S. Goligorsky, and E. Noiri Duality of nitric oxide in acute renal injury Semin Nephrol 19 1999 263 271
70. E. Noiri, T. Peresleni, and F. Miller In vivo targeting of inducible NO synthase with oligodeoxynucleotides protects rat kidney against ischemia J Clin Invest 97 1996 2377 2383
71. E. Noiri, A. Nakao, and K. Uchida Oxidative and nitrosative stress in acute renal ischemia Am J Physiol Renal Physiol 281 2001 F948 F957
72. J. Gailit, D. Colflesh, and I. Rabiner Redistribution and dysfunction of integrins in cultured renal epithelial cells exposed to oxidative stress Am J Physiol 264 1993 F149 F157
73. V. Romanov, E. Noiri, and G. Czerwinski Two novel probes reveal tubular and vascular Arg-Gly-Asp (RGD) binding sites in the ischemic rat kidney Kidney Int 52 1997 93 102
74. A. Wangsiripaisan, P.E. Gengaro, and C.L. Edelstein Role of polymeric Tamm-Horsfall protein in cast formation: oligosaccharide and tubular fluid ions Kidney Int 59 2001 932 940
75. P.C. Dagher Apoptosis in ischemic renal injury: roles of GTP depletion and p53 Kidney Int 66 2004 506 509
76. G.P. Kaushal, A.G. Basnakian, and S.V. Shah Apoptotic pathways in ischemic acute renal failure Kidney Int 66 2004 500 506
77. R. Bonegio, and W. Lieberthal Role of apoptosis in the pathogenesis of acute renal failure Curr Opin Nephrol Hypertens 11 2002 301 308
78. R. Oberbauer, M. Rohrmoser, and H. Regeler Apoptosis of tubular epithelial cells in donor kidney biopsies predicts early renal allograft function J Am Soc Nephrol 10 1999 2006 2013
79. P.M. Price, J. Megyesi, and R.L. Saf Irstein Cell cycle regulation: repair and regeneration in acute renal failure Kidney Int 66 2004 509 514
80. Q. Al Awqati, and J.A. Oliver Stem cells in the kidney Kidney Int 61 2002 387 395
81. M.R. Hammerman, and S.B. Miller Therapeutic use of growth factors in renal failure [editorial] J Am Soc Nephrol 5 1994 1 11
82. M.B. Rookmaaker, M.C. Verhaar, and A.J. Van Zonneveld Progenitor cells in the kidney: biology and therapeutic perspectives Kidney Int 66 2004 518 522
83. D.S. Krause, N.D. Theise, and M.I. Collector Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell Cell 105 2001 369 377
84. C.M. Verfaillie, M.F. Pera, and P.M. Lansdorp Stem cells: hype and reality Hematology (Am Soc Hematol Educ Program) 2002 369 391
85. T. Ito Stem cells of the adult kidney: where are you from? Nephrol Dial Transplant 18 2003 641 644
86. R. Poulsom, S.J. Forbes, and K. Hodivala-Dilke Bone marrow contributes to renal parenchymal turnover and regeneration J Pathol 195 2001 229 235
87. S. Kale, A. Karihaloo, and P.R. Clark Bone marrow stem cells contribute to repair of the ischemically injured renal tubule J Clin Invest 112 2003 42 49
88. M. Morigi, B. Imberti, and C. Zoja Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure J Am Soc Nephrol 15 2004 1794 1804
89. F. Togel, J. Isaac, and C. Westenfelder Hematopoietic stem cell mobilization-associated granulocytosis severely worsens acute renal failure J Am Soc Nephrol 15 2004 1261 1267
90. J.V. Bonventre, and A. Zuk Ischemic acute renal failure: an inflammatory disease? Kidney Int 66 2004 480 485
91. K.M. Park, J.Y. Byun, and C. Kramers Inducible nitric oxide synthase is an important contributor to prolonged protective effects of ischemic preconditioning in the mouse kidney J Biol Chem 278 2003 27256 27266
92. K.M. Park, A. Chen, and J.V. Bonventre Prevention of kidney ischemia/reperfusion-induced functional injury and JNK, p38, and MAPK kinase activation by remote ischemic pretreatment J Biol Chem 276 2001 11870 11876
93. K.M. Park, C. Kramers, and M. Vayssier-Taussat Prevention of kidney ischemia/reperfusion-induced functional injury, MAPK and MAPK kinase activation, and inflammation by remote transient ureteral obstruction J Biol Chem 277 2002 2040 2049
94. C.M. Pombo, J.V. Bonventre, and J. Avruch The stress-activated protein kinases are major c-Jun amino-terminal kinases activated by ischemia and reperfusion J Biol Chem 269 1994 26546 26551