메뉴 건너뛰기




Volumn 64, Issue 3, 2010, Pages 220-225

Metformin inhibits inflammatory angiogenesis in a murine sponge model

Author keywords

CCL2(MCP1 JE) collagen; Implant; TGF ; TNF ; VEGF

Indexed keywords

ACETYLGLUCOSAMINIDASE; COLLAGEN; CYTOKINE; HEMOGLOBIN; METFORMIN; MYELOPEROXIDASE; POLYESTER; POLYURETHAN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 77649232560     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2009.08.004     Document Type: Article
Times cited : (58)

References (36)
  • 2
    • 0029099086 scopus 로고
    • Efficacy of metformin in patients with non-insulin-dependent dibetes mellitus. The Multicenter Metformin Study Group
    • DeFronzo R.A., and Goodman A.M. Efficacy of metformin in patients with non-insulin-dependent dibetes mellitus. The Multicenter Metformin Study Group. N Engl J Med 333 (1995) 541-549
    • (1995) N Engl J Med , vol.333 , pp. 541-549
    • DeFronzo, R.A.1    Goodman, A.M.2
  • 3
    • 0034783579 scopus 로고    scopus 로고
    • The blooming of the French lilac
    • Witters L.A. The blooming of the French lilac. J Clin Invest 108 (2001) 1105-1107
    • (2001) J Clin Invest , vol.108 , pp. 1105-1107
    • Witters, L.A.1
  • 4
    • 38149091696 scopus 로고    scopus 로고
    • A review of thiazolidinediones and metformin in the treatment of type 2 diabetes with focus on cardiovascular complications
    • Molavi B., Rassouli N., Bagwe S., and Rasouli N. A review of thiazolidinediones and metformin in the treatment of type 2 diabetes with focus on cardiovascular complications. Vasc Health Risk Manag 3 6 (2007) 967-973
    • (2007) Vasc Health Risk Manag , vol.3 , Issue.6 , pp. 967-973
    • Molavi, B.1    Rassouli, N.2    Bagwe, S.3    Rasouli, N.4
  • 6
    • 33646105593 scopus 로고    scopus 로고
    • Metformin inhibits proinflammatory responses and nuclear factor-κB in human vascular wall cells
    • Isoda K., Young J.L., Zirlik A., et al. Metformin inhibits proinflammatory responses and nuclear factor-κB in human vascular wall cells. Arterioscler Thromb Vasc Biol 26 (2006) 611-617
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 611-617
    • Isoda, K.1    Young, J.L.2    Zirlik, A.3
  • 7
    • 67651095945 scopus 로고    scopus 로고
    • Metformin decreases angiogenesis via NF-kB and Erk1/2/Erk5 pathways by increasing antiangiogenic thrombospodin-1
    • Tan BK, Adya R, Chen J, Farhatullah S, Heutling D, Mitchell D, et al. Metformin decreases angiogenesis via NF-kB and Erk1/2/Erk5 pathways by increasing antiangiogenic thrombospodin-1. Cardiovasc Res 2009;83(3):566-74.
    • (2009) Cardiovasc Res , vol.83 , Issue.3 , pp. 566-574
    • Tan, B.K.1    Adya, R.2    Chen, J.3    Farhatullah, S.4    Heutling, D.5    Mitchell, D.6
  • 9
    • 34547764908 scopus 로고    scopus 로고
    • Metformin suppresses interleukin (IL)-1β-induced IL-8 production, aromatase activation, and proliferation of endometriotic stromal cells
    • Takemura Y., Osuga Y., Yoshino O., et al. Metformin suppresses interleukin (IL)-1β-induced IL-8 production, aromatase activation, and proliferation of endometriotic stromal cells. J Clin Endocrinol Metab 92 (2007) 3213-3218
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 3213-3218
    • Takemura, Y.1    Osuga, Y.2    Yoshino, O.3
  • 10
    • 21344456357 scopus 로고    scopus 로고
    • Signaling pathways involved in human vascular smooth muscle cell proliferation and matrix metalloproteinase-2 expression induced by leptin: inhibitory effect of metformin
    • Li L., Mamputu J.C., Wiernsperger N., and Renier G. Signaling pathways involved in human vascular smooth muscle cell proliferation and matrix metalloproteinase-2 expression induced by leptin: inhibitory effect of metformin. Diabetes 54 (2005) 2227-2234
    • (2005) Diabetes , vol.54 , pp. 2227-2234
    • Li, L.1    Mamputu, J.C.2    Wiernsperger, N.3    Renier, G.4
  • 11
    • 33751284806 scopus 로고    scopus 로고
    • Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells
    • Zakikhani M., Dowling R., Fantus I.G., Sonenberg N., and Pollak M. Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cells. Cancer Res 66 21 (2006) 10269-10273
    • (2006) Cancer Res , vol.66 , Issue.21 , pp. 10269-10273
    • Zakikhani, M.1    Dowling, R.2    Fantus, I.G.3    Sonenberg, N.4    Pollak, M.5
  • 12
    • 44849099894 scopus 로고    scopus 로고
    • The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level
    • Sahra I.B., Laurent K., Loubat A., et al. The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level. Oncogene 27 (2008) 3576-3586
    • (2008) Oncogene , vol.27 , pp. 3576-3586
    • Sahra, I.B.1    Laurent, K.2    Loubat, A.3
  • 13
    • 34547114031 scopus 로고    scopus 로고
    • Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth
    • Buzzai M., Jones R.G., Amaravadi R.K., et al. Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth. Cancer Res 67 14 (2007) 6745-6752
    • (2007) Cancer Res , vol.67 , Issue.14 , pp. 6745-6752
    • Buzzai, M.1    Jones, R.G.2    Amaravadi, R.K.3
  • 15
    • 0036324142 scopus 로고    scopus 로고
    • The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism
    • Hawley S.A., Gadalla A.E., Olsen G.S., and Hardie D.G. The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism. Diabetes 51 (2002) 2420-2425
    • (2002) Diabetes , vol.51 , pp. 2420-2425
    • Hawley, S.A.1    Gadalla, A.E.2    Olsen, G.S.3    Hardie, D.G.4
  • 16
    • 33847080728 scopus 로고    scopus 로고
    • AMP-activated protein kinase in metabolic control and insulin signaling
    • Towler M.C., and Hardie D.G. AMP-activated protein kinase in metabolic control and insulin signaling. Circ Res 100 (2007) 328-341
    • (2007) Circ Res , vol.100 , pp. 328-341
    • Towler, M.C.1    Hardie, D.G.2
  • 17
    • 41749120541 scopus 로고    scopus 로고
    • AMP-activated protein kinase activation as a strategy for protecting vascular endothelial function
    • Zou M.H., and Wu Y. AMP-activated protein kinase activation as a strategy for protecting vascular endothelial function. Clin Exp Pharmacol Physiol 35 (2008) 535-545
    • (2008) Clin Exp Pharmacol Physiol , vol.35 , pp. 535-545
    • Zou, M.H.1    Wu, Y.2
  • 18
    • 0037122766 scopus 로고    scopus 로고
    • Leptin stimulates fatty-acid oxidation by activating AM∅-activated protein kinase
    • Minokoshi Y., Kim Y.B., Peroni O.D., Fryer L.G., Muller C., Carling D., et al. Leptin stimulates fatty-acid oxidation by activating AM∅-activated protein kinase. Nature 415 (2002) 339-343
    • (2002) Nature , vol.415 , pp. 339-343
    • Minokoshi, Y.1    Kim, Y.B.2    Peroni, O.D.3    Fryer, L.G.4    Muller, C.5    Carling, D.6
  • 19
    • 33744976813 scopus 로고    scopus 로고
    • Metformin inhibits cytokine-induced nuclear factor κB activation via AMP-activated protein kinase activation in vascular endothelial cells
    • Hattori Y., Suzuki K., Hattori S., and Kasai K. Metformin inhibits cytokine-induced nuclear factor κB activation via AMP-activated protein kinase activation in vascular endothelial cells. Hypertension 47 (2006) 1183-1188
    • (2006) Hypertension , vol.47 , pp. 1183-1188
    • Hattori, Y.1    Suzuki, K.2    Hattori, S.3    Kasai, K.4
  • 20
    • 0028579731 scopus 로고
    • Cytokines and macrophages
    • Cavaillon J.M. Cytokines and macrophages. Biomed Pharmacother 48 10 (1994) 445-453
    • (1994) Biomed Pharmacother , vol.48 , Issue.10 , pp. 445-453
    • Cavaillon, J.M.1
  • 21
    • 0031910768 scopus 로고    scopus 로고
    • Sponge-induced angiogenesis in mice and the pharmacological reactivity of the neovasculature quantitated by a fluorimetric method
    • Andrade S.P., Machado R.D.P., Teixeira A.S., Belo A.V., Tarso A.M., and Beraldo W.T. Sponge-induced angiogenesis in mice and the pharmacological reactivity of the neovasculature quantitated by a fluorimetric method. Microvasc Res 54 (1997) 253-261
    • (1997) Microvasc Res , vol.54 , pp. 253-261
    • Andrade, S.P.1    Machado, R.D.P.2    Teixeira, A.S.3    Belo, A.V.4    Tarso, A.M.5    Beraldo, W.T.6
  • 23
    • 33644768265 scopus 로고    scopus 로고
    • Metformin prevents endotoxin-induced liver injury after partial hepatectomy
    • Bergheim I., Luyendyk J.P., Steele C., et al. Metformin prevents endotoxin-induced liver injury after partial hepatectomy. J Pharmacol Exp Ther 316 (2006) 1053-1061
    • (2006) J Pharmacol Exp Ther , vol.316 , pp. 1053-1061
    • Bergheim, I.1    Luyendyk, J.P.2    Steele, C.3
  • 24
    • 48849108755 scopus 로고    scopus 로고
    • Comparison of gene expression changes induced by biguanides in db/db mice liver
    • Heishi M., Hayashi K., Ichihara J., et al. Comparison of gene expression changes induced by biguanides in db/db mice liver. J Toxicol Sci 33 (2008) 339-347
    • (2008) J Toxicol Sci , vol.33 , pp. 339-347
    • Heishi, M.1    Hayashi, K.2    Ichihara, J.3
  • 26
    • 43749094322 scopus 로고    scopus 로고
    • Mechanisms of wound healing responses in lupus-prone New Zealand White mouse strain
    • Campos P.P., Bakhle Y.S., and Andrade S.P. Mechanisms of wound healing responses in lupus-prone New Zealand White mouse strain. Wound Rep Reg 16 3 (2008) 416-424
    • (2008) Wound Rep Reg , vol.16 , Issue.3 , pp. 416-424
    • Campos, P.P.1    Bakhle, Y.S.2    Andrade, S.P.3
  • 27
    • 0036842215 scopus 로고    scopus 로고
    • Vascular permeability factor/Vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy
    • Dvorak H.F. Vascular permeability factor/Vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J Clin Oncol 21 (2002) 4368-4380
    • (2002) J Clin Oncol , vol.21 , pp. 4368-4380
    • Dvorak, H.F.1
  • 28
    • 0029910066 scopus 로고    scopus 로고
    • The role of vascular endothelial growth factor in a murine chronic granulomatous tissue air pouch model of angiogenesis
    • Appleton I., Brown N.J., Willis D., et al. The role of vascular endothelial growth factor in a murine chronic granulomatous tissue air pouch model of angiogenesis. J Pathol 180 (1996) 90-94
    • (1996) J Pathol , vol.180 , pp. 90-94
    • Appleton, I.1    Brown, N.J.2    Willis, D.3
  • 29
    • 0035431418 scopus 로고    scopus 로고
    • Clinical trials referral resource: current clinical trials of the anti-VEGF monoclonal antibody bevacizumab
    • Chen H.X., Gore-Langton R.E., and Cheson B.D. Clinical trials referral resource: current clinical trials of the anti-VEGF monoclonal antibody bevacizumab. Oncology 15 (2001) 1023-1026
    • (2001) Oncology , vol.15 , pp. 1023-1026
    • Chen, H.X.1    Gore-Langton, R.E.2    Cheson, B.D.3
  • 30
    • 0029117223 scopus 로고
    • Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells
    • Ikeda E., Achen M.G., Breier G., and Risau W. Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J Biol Chem 270 (1995) 19761-19766
    • (1995) J Biol Chem , vol.270 , pp. 19761-19766
    • Ikeda, E.1    Achen, M.G.2    Breier, G.3    Risau, W.4
  • 31
    • 0032852528 scopus 로고    scopus 로고
    • Molecular and biological properties of vascular endothelial growth factor
    • Ferrara N. Molecular and biological properties of vascular endothelial growth factor. J Mol Med 77 (1999) 527-543
    • (1999) J Mol Med , vol.77 , pp. 527-543
    • Ferrara, N.1
  • 32
    • 0042733154 scopus 로고    scopus 로고
    • AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress
    • Nagata D., Mogi M., and Walsh K. AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress. J Biol Chem 278 (2003) 31000-31006
    • (2003) J Biol Chem , vol.278 , pp. 31000-31006
    • Nagata, D.1    Mogi, M.2    Walsh, K.3
  • 33
    • 18044393806 scopus 로고    scopus 로고
    • AMP-activated protein kinase signaling stimulates VEGF expression and angiogenesis in skeletal muscle
    • Ouchi N., Shibata R., and Walsh K. AMP-activated protein kinase signaling stimulates VEGF expression and angiogenesis in skeletal muscle. Circ Res 96 (2005) 838-846
    • (2005) Circ Res , vol.96 , pp. 838-846
    • Ouchi, N.1    Shibata, R.2    Walsh, K.3
  • 34
    • 58149156184 scopus 로고    scopus 로고
    • Therapeutic metformin/AMPK activation promotes angiogenic phenotype in the ERalpha negative MDA-MB-435 breast cancer model
    • 113(1):101-11
    • Phoenix K.N., Vumbaca F., and Claffey K.P. Therapeutic metformin/AMPK activation promotes angiogenic phenotype in the ERalpha negative MDA-MB-435 breast cancer model. Breast Cancer Res Treat (2008) 113(1):101-11
    • (2008) Breast Cancer Res Treat
    • Phoenix, K.N.1    Vumbaca, F.2    Claffey, K.P.3
  • 35
    • 34447264741 scopus 로고    scopus 로고
    • No effects of simvastatin and metformin on inflammation and insulin resistance in individuals with mild metabolic syndrome
    • Bulcão C., Ribeiro-Filho F.F., Sañudo A., and Roberta Ferreira S.G. No effects of simvastatin and metformin on inflammation and insulin resistance in individuals with mild metabolic syndrome. Am J Cardiovasc Drugs 7 3 (2007) 219-224
    • (2007) Am J Cardiovasc Drugs , vol.7 , Issue.3 , pp. 219-224
    • Bulcão, C.1    Ribeiro-Filho, F.F.2    Sañudo, A.3    Roberta Ferreira, S.G.4
  • 36
    • 33744537874 scopus 로고    scopus 로고
    • Metformin prevents alcohol-induced liver injury in the mouse: critical role of plasminogen activator inhibitor-1
    • Bergheim I., Guo L., and Davis M.A. Metformin prevents alcohol-induced liver injury in the mouse: critical role of plasminogen activator inhibitor-1. Gastroenterology 130 (2006) 2099-2112
    • (2006) Gastroenterology , vol.130 , pp. 2099-2112
    • Bergheim, I.1    Guo, L.2    Davis, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.