Synthesis of theophylline derivatives and study of their activity as antagonists at adenosine receptors

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 6, 2010, Pages 2081-2088

  Hierrezuelo, Jesús ^a   Manuel Lopez Romero J ^a   Rico, Rodrigo ^a   Brea, José ^b   Isabel Loza, M ^b   Cai, Chengzhi ^c   Algarra, Manuel ^d  

^a UNIVERSITY OF MÁLAGA   (Spain)

^b UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^c University of Houston   (United States)

^d UNIVERSITY OF PORTO   (Portugal)

Author keywords

Azides; Caffeine derivatives; Heterocyclic compound; Oligo(ethylene glycol); Schiff bases; Silicon surface

Indexed keywords

ADENOSINE A2A RECEPTOR; ADENOSINE A2B RECEPTOR; AZIDE; CAFFEINE DERIVATIVE; OLIGO(ETHYLENE GLYCOL)THEOPHYLLINE DERIVATIVE; SCHIFF BASE; SILICON; THEOPHYLLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; DRUG SELECTIVITY; DRUG SOLUBILITY; DRUG SYNTHESIS; HYDROSILYLATION; REACTION ANALYSIS; RECEPTOR BLOCKING; STRUCTURE ACTIVITY RELATION; SURFACE PROPERTY;

BINDING, COMPETITIVE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MOLECULAR STRUCTURE; RECEPTORS, PURINERGIC P1; RECOMBINANT PROTEINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THEOPHYLLINE;

EID: 77649232354     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.02.014     Document Type: Article

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