Simple and accurate determination of CYP2D6 gene copy number by a loop-mediated isothermal amplification method and an electrochemical DNA chip

Clinica Chimica Acta

Volumn 411, Issue 7-8, 2010, Pages 568-573

  Nakamura, Naoko ^a   Fukuda, Tsuyoshi ^b,c   Nonen, Shinpei ^b,d   Hashimoto, Koji ^a   Azuma, Junichi ^b,d   Gemma, Nobuhiro ^a  

^a TOSHIBA CORPORATION   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

CYP2D6; Electrochemical DNA chip; Gene copy number; Loop mediated isothermal amplification method; Personalized medicine

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 2D6; CYTOCHROME P450 2D7P; CYTOCHROME P450 2D8P; UNCLASSIFIED DRUG;

ARTICLE; DNA FRAGMENTATION; DNA HYBRIDIZATION; DNA MICROARRAY; DNA SEQUENCE; ELECTROCHEMISTRY; FEASIBILITY STUDY; GENE AMPLIFICATION; GENE DELETION; GENE DUPLICATION; GENOTYPE; HAPLOTYPE; HUMAN; ISOTHERM; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SOUTHERN BLOTTING;

ALLELES; BASE SEQUENCE; CYTOCHROME P-450 CYP2D6; DNA; ELECTROCHEMISTRY; GENE DOSAGE; GENOTYPE; HUMANS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID AMPLIFICATION TECHNIQUES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SENSITIVITY AND SPECIFICITY; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA;

EID: 77649187828     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2010.01.017     Document Type: Article

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