Mechanistic investigation on pressure dependency of Heckel parameter

International Journal of Pharmaceutics

Volumn 389, Issue 1-2, 2010, Pages 66-73

  Patel, Sarsvatkumar ^a   Kaushal, Aditya Mohan ^a   Bansal, Arvind Kumar ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Apparent mean yield pressure; Compaction; Heckel equation; Plastic energy; Strain hardening

Indexed keywords

CALCIUM PHOSPHATE DIBASIC; IBUPROFEN; METHYLCELLULOSE; MICROCRYSTALLINE CELLULOSE; PARACETAMOL; SODIUM CHLORIDE;

ARTICLE; DRUG MANUFACTURE; ENERGY YIELD; HARDNESS; MATHEMATICAL ANALYSIS; MECHANICS; PRESSURE; PRIORITY JOURNAL; STRENGTH; TABLET COMPRESSION; VISCOELASTICITY;

ACETAMINOPHEN; CALCIUM PHOSPHATES; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; ELASTICITY; EXCIPIENTS; IBUPROFEN; METHYLCELLULOSE; POWDERS; PRESSURE; SODIUM CHLORIDE; TABLETS; TECHNOLOGY, PHARMACEUTICAL;

EID: 77649181645     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.01.020     Document Type: Article

References (52)

1. Antikainen O., and Yliruusi J. Determining the compression behavior of pharmaceutical powders from the force-distance compression profile. Int. J. Pharm. 252 (2003) 253-261
2. Armstrong N.A., and Palfrey L.P. The effect of machine speed on the consolidation of four directly compressible tablet diluents. J. Pharm. Pharmacol. 41 (1989) 149-151
3. Arruda E.M., Boyce M.C., and Jayachandran R. Effects of strain rate, temperature and thermomechanical coupling on the finite strain deformation of glassy polymers. Mech. Mater. 19 (1995) 193-212
4. Bandyopadhyay R., and Grant D.J.W. Plasticity and slip system of plate-shaped crystals of l-lysine monohydrochloride dihydrate. Pharm. Res. 19 (2002) 491-496
5. Bolhuis G.K., Eissens A.C., and Zoestbergen E. DC calcium lactate, a new filler-binder for direct compaction of tablets. Int. J. Pharm. 221 (2001) 77-86
6. Boyce M.C., Socrate S., and Llana P.G. Constitutive model for the finite deformation stress-strain behavior of poly(ethylene terephthalate) above the glass transition. Polymer 41 (2000) 2183-2201
7. Busignies V., et al. Compaction behaviour and new predictive approach to the compressibility of binary mixtures of pharmaceutical excipients. Eur. J. Pharm. Biopharm. 64 (2006) 66-74
8. David S.T., and Augsburger L.L. Plastic flow during compression of directly compressible fillers and its effect on tablet strength. J. Pharm. Sci. 66 (1977) 155-159
9. Denny P.J. Compaction equations: a compression of the Heckel and Kawakita equations. Powder Technol. 127 (2002) 162-172
10. Eriksson M., and Alderborn G. The effect of particle fragmentation and deformation, the interparticulate bond formation process during powder compaction. Pharm. Res. 12 (1995) 1031-1039
11. Gabaude C.M., Guillot M., Gautier J.C., Saudemon P., and Chulia D. Effects of true density, compacted mass, compression speed, and punch deformation on the mean yield pressure. J. Pharm. Sci. 88 (1999) 725-730
12. Garekani H.A., Ford J.L., Rubinstein M.H., and Rajabi-Siahboomi A.R. Effect of compression force, compression speed, and particle size on the compression properties of paracetamol. Drug Dev. Ind. Pharm. 27 (2001) 935-942
13. Hardy I.J., Cook W.G., and Melia C.D. Compression and compaction properties of plasticised high molecular weight hydroxypropyl methylcellulose (HPMC) as a hydrophilic matrix carrier. Int. J. Pharm. 311 (2006) 26-32
14. Hassanpour A., and Ghadiri M. Distinct element analysis and experimental evaluation of the Heckel analysis of bulk powder compression. Powder Technol. 141 (2004) 251-261
15. Heckel R.W. An analysis of powder compaction phenomena. Trans. Metall. Soc. AIME 221 (1961) 1001-1008
16. Heckel R.W. Density-pressure relationships in powder compaction. Trans. Metall. Soc. AIME 221 (1961) 671-675
17. Hiestand E.N. Dispersion forces and plastic deformation in tablet bond. J. Pharm. Sci. 74 (1985) 768-770
18. Hirsch P.B. Work hardening. In: Hirsch P.B. (Ed). The Physics of Metals (1975), Cambridge University Press, London
19. Hoblitzell J.R., and Rhodes C.T. Determination of a relationship between force-displacement and force-time curves. Drug Dev. Ind. Pharm. 16 (1990) 201-229
20. Ilkka J., and Paronen P. Prediction of the compression behavior of powder mixtures by the Heckel equation. Int. J. Pharm. 94 (1993) 181-187
21. Jain M., Lloyd D.J., and Macewen S.R. Hardening laws, surface roughness and biaxial tensile limit strains of sheet aluminium alloys. Int. J. Mech. Sci. 38 (1996) 219-232
22. Johnston W.G., and Gilman J.J. Dislocation velocities, dislocation densities and plastic flow in lithium fluoride crystals. J. Appl. Phys. 30 (1959) 129
23. Joiris E., Di Martino P., Berneron C., Guyot-Hermann A.M., and Guyot J.C. Compression behavior of orthorhombic paracetamol. Pharm. Res. 15 (1998) 1122-1130
24. Katikaneni P.R., Upadrashta S.M., Rowlings E., Neau S.H., and Hileman G.A. Consolidation of ethylcellulose: effect of particle size, press speed, and lubricants. Int. J. Pharm. 117 (1995) 13-21
25. Malamataris S., Bin Baie S., and Pilpel N. Plasto-elasticity and tableting of paracetamol, Avicel and other powders. J. Pharm. Pharmacol. 36 (1984) 616-617
26. Malamataris S., Hatjichristos T.H., and Rees J.E. Apparent compressive Young's modulus and strength isotropy of compacts formed from binary powder mixes. Int. J. Pharm. 141 (1996) 101-108
27. Matz C., Bauer-Brandl A., Rigassi T., Schubert R., and Becker D. On the accuracy of a new displacement instrumentation for rotary tablet presses. Drug Dev. Ind. Pharm. 25 (1999) 117-130
28. Muller F.X., and Augsburger L.L. The role of the displacement-time waveform in the determination of Heckel behaviour under dynamic conditions in a compaction simulator and a fully instrumented rotary tablet machine. J. Pharm. Pharmacol. 46 (1994) 468-475
29. Nadgornyi E. Dislocation dynamics and mechanical properties of crystals. Prog. Mater. Sci. 31 (1988) 1-10
30. Nokhodchi A., Ford J.L., Rowe P.H., and Rubinstein M.H. The effect of moisture on the Heckel and energy analysis of hydroxypropyl methylcellulose 2208 (HPMC K4M). J. Pharm. Pharmacol. 48 (1996) 1122-1127
31. Oates R.J., and Mitchell A.G. Calculation of punch displacement and work of powder compaction on a rotary tablet press. J. Pharm. Pharmacol. 41 (1989) 517-523
32. Paronen P. Heckel plots as indicators of elastic properties of pharmaceuticals. Drug Dev. Ind. Pharm. 12 (1986) 1903-1912
33. Patel S., Kaushal A.M., and Bansal A.K. Effect of particle size and compression force on compaction behavior and derived mathematical parameters of compressibility. Pharm. Res. 24 (2007) 111-124
34. Ragnarsson G., and Sjogren J. Force-displacement measurements in tableting. J. Pharm. Pharmacol. 37 (1985) 146-150
35. Ramberger R., and Burger A. On the application of the Heckel and Kawakita equation to powder compaction. Powder Technol. 43 (1985) 1-9
36. Rees J.E., and Rue P.J. Time-dependent deformation of some direct compression excipients. J. Pharm. Pharmacol. 30 (1978) 601-607
37. Rice J.R., and Thomson R. Ductile versus brittle behaviour of crystals. Philos. Mag. 29 (1974) 73
38. Roberts R.J., and Rowe R.C. The Young's Modulus of pharmaceutical materials. Int. J. Pharm. 37 (1987) 15-18
39. Rumpf H. The strength of granules and agglomerates. In: Knepper W.A. (Ed). Agglomeration (1962), Wiley Interscience, New York 379-418
40. Shapiro, I., 1944. Ph.D. Thesis. University of Minnesota.
41. Sing W.M., and Rao K.P. Role of strain-hardening laws in the prediction of forming limit curves. J. Mater. Process. Technol. 63 (1997) 105-110
42. Sonnergaard J.M. A critical evaluation of the Heckel equation. Int. J. Pharm. 193 (1999) 63-71
43. Sonnergaard J.M. Impact of particle density and initial volume on mathematical compression models. Eur. J. Pharm. Sci. 11 (2000) 307-315
44. Suihko E., et al. Complexation with tolbutamide modifies the physicochemical and tableting properties of hydroxypropyl-[beta]-cyclodextrin. Int. J. Pharm. 215 (2001) 137-145
45. Suihno E., Lehto V., Ketolainen J., Laine E., and Paronen P. Dynamic solid state and tabletting properties of four theophylline forms. Int. J. Pharm. 217 (2001) 225-236
46. Sun C., and Grant D.J. Compaction properties of l-lysine salts. Pharm. Res. 18 (2001) 281-286
47. Sun C., and Grant D.J. Influence of elastic deformation of particles on Heckel analysis. Pharm. Dev. Technol. 6 (2001) 193-200
48. Taylor G.I. The mechanism of plastic deformation of crystals. Proc. R. Soc. A 145 (1934) 362-388
49. Walker E.E. The properties of powder. Part VI. The compressibility of powders. Trans. Faraday Soc. 19 (1923) 73-82
50. Wu S.-J., and Sun C.C. Insensitivity of compaction properties of brittle granules to size enlargement by roller compaction. J. Pharm. Sci. 96 (2007) 1445-1448
51. Zhang Y., Law Y., and Chakrabarti S. Physical properties and compact analysis of commonly used direct compression binders. AAPS PharmSciTech. 4 (2003) E62
52. Zuurman K., Riepma K.A., Bolhuis G.K., Vromans H., and Lerk C.F. The relationship between bulk density and compactibility of lactose granulations. Int. J. Pharm. 102 (1994) 1-9