Complexation with tolbutamide modifies the physicochemical and tableting properties of hydroxypropyl-β-cyclodextrin

International Journal of Pharmaceutics

Volumn 215, Issue 1-2, 2001, Pages 137-145

  Suihko, Eero ^a   Korhonen, Ossi ^a   Järvinen, Tomi ^a   Ketolainen, Jarkko ^a   Jarho, Pekka ^a   Laine, Ensio ^b   Paronen, Petteri ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

Freeze drying; Hydroxypropyl cyclodextrin; Moisture sorption desorption; Spray drying; Tableting; Tolbutamide

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; TOLBUTAMIDE; WATER;

AQUEOUS SOLUTION; ARTICLE; COMPLEX FORMATION; DESORPTION; DRUG SOLUBILITY; DRUG STABILITY; FREEZE DRYING; HUMIDITY; MOISTURE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; TABLET COMPRESSION; TABLET MANUFACTURE; WATER CONTENT; WETTABILITY;

BETA-CYCLODEXTRINS; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLODEXTRINS; DRUG COMPOUNDING; EXCIPIENTS; FREEZE DRYING; SPECTROPHOTOMETRY, ULTRAVIOLET; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TABLETS; TOLBUTAMIDE; X-RAY DIFFRACTION;

EID: 0035857727     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00682-7     Document Type: Article

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