Differential alteration of heat shock protein 90 in mice modifies glucocorticoid receptor function and susceptibility to trauma

Journal of Neurotrauma

Volumn 27, Issue 2, 2010, Pages 373-381

  Shen, Hai Ying ^a,b   Zhao, Yan ^a   Chen, Xing Yun ^a   Xiong, Ren Ping ^a   Lu, Jin Li ^a   Chen, Jiang Fan ^b   Chen, Li Yong ^c   Zhou, Yuan Guo ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Geldanamycin; Glucocorticoid receptor; Heat shock protein; Traumatic susceptibility; Whole body blast injury

Indexed keywords

ADENOSINE TRIPHOSPHATE; GELDANAMYCIN; GLUCOCORTICOID RECEPTOR; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; BINDING AFFINITY; BLAST INJURY; C57BL 6 MOUSE; CONTROLLED STUDY; CYTOSOL; DIMERIZATION; GENETIC IDENTIFICATION; GENETIC VARIABILITY; MALE; MOLECULAR MECHANICS; MORTALITY; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; STRESS; WHOLE BODY BLAST INJURY;

ANIMALS; BENZOQUINONES; BLAST INJURIES; BLOTTING, WESTERN; ENZYME INHIBITORS; GENETIC PREDISPOSITION TO DISEASE; HSP90 HEAT-SHOCK PROTEINS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; LACTAMS, MACROCYCLIC; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PITUITARY-ADRENAL SYSTEM; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, GLUCOCORTICOID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STRESS, PHYSIOLOGICAL; WOUNDS AND INJURIES;

EID: 77649150171     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.2009.0926     Document Type: Article

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