Molecular Basis for Shared Cytokine Recognition Revealed in the Structure of an Unusually High Affinity Complex between IL-13 and IL-13Rα2

Structure

Volumn 18, Issue 3, 2010, Pages 332-342

  Lupardus, Patrick J ^a   Birnbaum, Michael E ^a   Garcia, K Christopher ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

MOLIMMUNO; PROTEINS

Indexed keywords

ALANINE; CYTOKINE; INTERLEUKIN 13; INTERLEUKIN 13 RECEPTOR ALPHA1; INTERLEUKIN 13 RECEPTOR ALPHA2;

ARTICLE; BINDING KINETICS; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; HUMAN; ISOTHERMAL TITRATION CALORIMETRY; MUTAGENESIS; MUTANT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; SURFACE PLASMON RESONANCE; THERMODYNAMICS;

ALANINE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYTOKINES; HUMANS; INTERLEUKIN-13; INTERLEUKIN-13 RECEPTOR ALPHA2 SUBUNIT; KINETICS; MODELS, MOLECULAR; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION;

EID: 77649146245     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2010.01.003     Document Type: Article

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