-
1
-
-
34447626493
-
Glycogen synthase kinase 3: a key regulator of cellular fate
-
Forde JE, Dale TC. Glycogen synthase kinase 3: a key regulator of cellular fate. Cell Mol Life Sci. 2007, 64:1930-44.
-
(2007)
Cell Mol Life Sci.
, vol.64
, pp. 1930-1944
-
-
Forde, J.E.1
Dale, T.C.2
-
3
-
-
34250222104
-
In search of the Holy Grail for the treatment of neurodegenerative disorders: has a simple cation been overlooked
-
Chuang DM, Manji HK. In search of the Holy Grail for the treatment of neurodegenerative disorders: has a simple cation been overlooked. Biol Psychiatry. 2007, 62:4-6.
-
(2007)
Biol Psychiatry.
, vol.62
, pp. 4-6
-
-
Chuang, D.M.1
Manji, H.K.2
-
4
-
-
33745466932
-
Targeting glycogen synthase kinase-3 in the CNS: implications for the development of new treatments for mood disorders
-
Gould TD, Picchini AM, Einat H. Targeting glycogen synthase kinase-3 in the CNS: implications for the development of new treatments for mood disorders. Curr Drug Targets. 2006, 7:1399-409.
-
(2006)
Curr Drug Targets.
, vol.7
, pp. 1399-1409
-
-
Gould, T.D.1
Picchini, A.M.2
Einat, H.3
et al4
-
6
-
-
20544437694
-
Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs
-
Gould TD, Manji HK. Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs. Neuropsychopharmacology. 2005, 30:1223-337.
-
(2005)
Neuropsychopharmacology.
, vol.30
, pp. 1223-1337
-
-
Gould, T.D.1
Manji, H.K.2
-
7
-
-
36148942761
-
GSK-3 inhibitors for Alzheimer's disease
-
Avila J, Hernández F. GSK-3 inhibitors for Alzheimer's disease. Expert Rev Neurother. 2007, 7:1527-33.
-
(2007)
Expert Rev Neurother.
, vol.7
, pp. 1527-1533
-
-
Avila, J.1
Hernández, F.2
-
8
-
-
34249689633
-
Inhibition of glycogen synthase kinase-3beta protects dopaminergic neurons from MPTP toxicity
-
Wang W, Yang Y, Ying C. Inhibition of glycogen synthase kinase-3beta protects dopaminergic neurons from MPTP toxicity. Neuropharmacology. 2007, 52:1678-84.
-
(2007)
Neuropharmacology.
, vol.52
, pp. 1678-1684
-
-
Wang, W.1
Yang, Y.2
Ying, C.3
et al4
-
9
-
-
33646795341
-
Targeting GSK-3: a promising approach for cancer therapy
-
Ougolkov AV, Billadeau DD. Targeting GSK-3: a promising approach for cancer therapy. Future Oncol. 2006, 2:91-100.
-
(2006)
Future Oncol.
, vol.2
, pp. 91-100
-
-
Ougolkov, A.V.1
Billadeau, D.D.2
-
10
-
-
34249676180
-
Lithium suppresses cell proliferation by interrupting E2F-DNA interaction and subsequently reducing S-phase gene expression in prostate cancer
-
Sun A, Shanmugam I, Song J. Lithium suppresses cell proliferation by interrupting E2F-DNA interaction and subsequently reducing S-phase gene expression in prostate cancer. Prostate. 2007, 67:976-88.
-
(2007)
Prostate.
, vol.67
, pp. 976-988
-
-
Sun, A.1
Shanmugam, I.2
Song, J.3
et al4
-
11
-
-
39049107744
-
GSK-3beta regulates cyclin D1 expression: a new target for chemotherapy
-
Takahashi-Yanaga F, Sasaguri T. GSK-3beta regulates cyclin D1 expression: a new target for chemotherapy. Cell Signal. 2008, 20:581-9.
-
(2008)
Cell Signal.
, vol.20
, pp. 581-589
-
-
Takahashi-Yanaga, F.1
Sasaguri, T.2
-
12
-
-
0036295233
-
Glycogen synthase kinase-3 inhibition by lithium and beryllium suggests the presence of two magnesium binding sites
-
Ryves WJ, Dajani R, Pearl L. Glycogen synthase kinase-3 inhibition by lithium and beryllium suggests the presence of two magnesium binding sites. Biochem Biophys Res Commun. 2002, 290:967-72.
-
(2002)
Biochem Biophys Res Commun.
, vol.290
, pp. 967-972
-
-
Ryves, W.J.1
Dajani, R.2
Pearl, L.3
et al4
-
13
-
-
34547497856
-
Glycogen synthase kinase-3 is involved in the regulation of the cell cycle in cerebellar granule cells
-
Yeste-Velasco M, Folch J, Trullàs R. Glycogen synthase kinase-3 is involved in the regulation of the cell cycle in cerebellar granule cells. Neuropharmacology. 2007, 53:295-307.
-
(2007)
Neuropharmacology.
, vol.53
, pp. 295-307
-
-
Yeste-Velasco, M.1
Folch, J.2
Trullàs, R.3
et al4
-
14
-
-
0344731445
-
Lithium induces morphological differentiation of mouse neuroblastoma cells
-
García-Pérez J, Avila J, Díaz-Nido J. Lithium induces morphological differentiation of mouse neuroblastoma cells. J Neurosci Res. 1999, 57:261-70.
-
(1999)
J Neurosci Res.
, vol.57
, pp. 261-270
-
-
García-Pérez, J.1
Avila, J.2
Díaz-Nido, J.3
-
15
-
-
33846460869
-
Lithium increases expression of p21(WAF/Cip1) and survivin in human glioblastoma cells
-
Karlovic D, Jakopec S, Dubravcic K. Lithium increases expression of p21(WAF/Cip1) and survivin in human glioblastoma cells. Cell Biol Toxicol. 2007, 23:83-90.
-
(2007)
Cell Biol Toxicol.
, vol.23
, pp. 83-90
-
-
Karlovic, D.1
Jakopec, S.2
Dubravcic, K.3
et al4
-
16
-
-
0035854803
-
Lithium inhibits cell cycle progression and induces stabilization of p53 in bovine aortic endothelial cells
-
Mao CD, Hoang P, DiCorleto PE. Lithium inhibits cell cycle progression and induces stabilization of p53 in bovine aortic endothelial cells. J. Biol. Chem. 2001, 276:26180-8.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 26180-26188
-
-
Mao, C.D.1
Hoang, P.2
DiCorleto, P.E.3
-
17
-
-
0041831195
-
Glycogen synthase kinase-3 inhibitors protect central neurons against excitotoxicity
-
Facci L, Stevens DA, Skaper SD. Glycogen synthase kinase-3 inhibitors protect central neurons against excitotoxicity. Neuroreport. 2003, 14:1467-70.
-
(2003)
Neuroreport.
, vol.14
, pp. 1467-1470
-
-
Facci, L.1
Stevens, D.A.2
Skaper, S.D.3
-
18
-
-
0033776383
-
Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription
-
Coghlan MP, Culbert AA, Cross DA. Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription. Chem Biol. 2007, 88:793-803.
-
(2007)
Chem Biol.
, vol.88
, pp. 793-803
-
-
Coghlan, M.P.1
Culbert, A.A.2
Cross, D.A.3
et al4
-
19
-
-
33746239119
-
Glycogen synthase kinase-3beta positively regulates the proliferation of human ovarian cancer cells
-
Cao Q, Lu X, Feng YJ. Glycogen synthase kinase-3beta positively regulates the proliferation of human ovarian cancer cells. Cell Res. 2006, 16:671-7.
-
(2006)
Cell Res.
, vol.16
, pp. 671-677
-
-
Cao, Q.1
Lu, X.2
Feng, Y.J.3
-
20
-
-
33745345286
-
Lithium treatment induces a marked proliferation of primarily principal cells in rat kidney inner medullary collecting duct
-
Christensen BM, Kim YH, Kwon TH. Lithium treatment induces a marked proliferation of primarily principal cells in rat kidney inner medullary collecting duct. Am J Physiol Renal Physiol. 2006, 291:F39-48.
-
(2006)
Am J Physiol Renal Physiol.
, vol.291
-
-
Christensen, B.M.1
Kim, Y.H.2
Kwon, T.H.3
et al4
-
21
-
-
20344399386
-
Lithium-mediated downregulation of PKB/Akt and cyclin E with growth inhibition in hepatocellular carcinoma cells
-
Erdal E, Ozturk N, Cagatay T. Lithium-mediated downregulation of PKB/Akt and cyclin E with growth inhibition in hepatocellular carcinoma cells. Int J Cancer. 2005, 115:903-10.
-
(2005)
Int J Cancer.
, vol.115
, pp. 903-910
-
-
Erdal, E.1
Ozturk, N.2
Cagatay, T.3
et al4
-
22
-
-
7644220896
-
Inhibition of glycogen synthase kinase-3 represses androgen receptor activity andprostate cancer cell growth
-
Mazor M, Kawano Y, Zhu H. Inhibition of glycogen synthase kinase-3 represses androgen receptor activity andprostate cancer cell growth. Oncogene. 2004, 23:7882-92.
-
(2004)
Oncogene.
, vol.23
, pp. 7882-7892
-
-
Mazor, M.1
Kawano, Y.2
Zhu, H.3
et al4
-
24
-
-
34147168760
-
Inactivation of glycogen synthase kinase-3beta, a downstream target of the raf-1 pathway, is associated with growth suppression in medullary thyroid cancer cells
-
Kunnimalaiyaan M, Vaccaro AM, Ndiaye MA. Inactivation of glycogen synthase kinase-3beta, a downstream target of the raf-1 pathway, is associated with growth suppression in medullary thyroid cancer cells. Mol Cancer Ther. 2007, 6:1151-8.
-
(2007)
Mol Cancer Ther.
, vol.6
, pp. 1151-1158
-
-
Kunnimalaiyaan, M.1
Vaccaro, A.M.2
Ndiaye, M.A.3
et al4
-
25
-
-
13644254946
-
Comparative analysis of the effects of four mood stabilizers in SH-SY5Y cells and in primary neurons
-
Di Daniel E, Mudge AW, Maycox PR. Comparative analysis of the effects of four mood stabilizers in SH-SY5Y cells and in primary neurons. Bipolar Disord. 2005, 7:33-41.
-
(2005)
Bipolar Disord.
, vol.7
, pp. 33-41
-
-
Di Daniel, E.1
Mudge, A.W.2
Maycox, P.R.3
-
26
-
-
0032533225
-
Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization
-
Diehl JA, Cheng M, Roussel MF. Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev. 1998, 15:3499-511.
-
(1998)
Genes Dev.
, vol.15
, pp. 3499-3511
-
-
Diehl, J.A.1
Cheng, M.2
Roussel, M.F.3
et al4
-
27
-
-
16444380336
-
Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity
-
Dong J, Peng J, Zhang H. Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity. Cancer Res. 2005, 65:1961-72.
-
(2005)
Cancer Res.
, vol.65
, pp. 1961-1972
-
-
Dong, J.1
Peng, J.2
Zhang, H.3
et al4
-
28
-
-
1942537708
-
The significance of the Wnt pathway in the pathology of human cancers
-
Karim R, Tse G, Putti T. The significance of the Wnt pathway in the pathology of human cancers. Pathology. 2004, 36:120-8.
-
(2004)
Pathology.
, vol.36
, pp. 120-128
-
-
Karim, R.1
Tse, G.2
Putti, T.3
et al4
-
29
-
-
9244239811
-
G1 cell-cycle control and cancer
-
Massagué J. G1 cell-cycle control and cancer. Nature. 2004, 432:298-306.
-
(2004)
Nature.
, vol.432
, pp. 298-306
-
-
Massagué, J.1
-
31
-
-
0041829415
-
Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene
-
Hiratsuka M, Inoue T, Toda T. Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene. Biochem Biophys Res Commun. 2003, 309:558-66.
-
(2003)
Biochem Biophys Res Commun.
, vol.309
, pp. 558-566
-
-
Hiratsuka, M.1
Inoue, T.2
Toda, T.3
et al4
-
32
-
-
0347416824
-
Rotenone induces disassembly of the Golgi apparatus in the rat dopaminergic neuroblastoma B65 cell line
-
Diaz-Corrales FJ, Asanuma M, Miyazaki I. Rotenone induces disassembly of the Golgi apparatus in the rat dopaminergic neuroblastoma B65 cell line. Neurosci Lett. 2004, 354:59-63.
-
(2004)
Neurosci Lett.
, vol.354
, pp. 59-63
-
-
Diaz-Corrales, F.J.1
Asanuma, M.2
Miyazaki, I.3
et al4
-
33
-
-
33847053144
-
SIRT2, a tubulin deacetylase, acts to block the entry to chromosome condensation in response to mitotic stress
-
Inoue T, Hiratsuka M, Osaki M. SIRT2, a tubulin deacetylase, acts to block the entry to chromosome condensation in response to mitotic stress. Oncogene. 2007, 26:945-57.
-
(2007)
Oncogene.
, vol.26
, pp. 945-957
-
-
Inoue, T.1
Hiratsuka, M.2
Osaki, M.3
et al4
-
34
-
-
34248151365
-
The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation
-
Inoue T, Hiratsuka M, Osaki M. The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation. Cell Cycle. 2007, 6:1011-88.
-
(2007)
Cell Cycle.
, vol.6
, pp. 1011-1088
-
-
Inoue, T.1
Hiratsuka, M.2
Osaki, M.3
et al4
-
35
-
-
33846523617
-
Targeted anti-mitotic therapies: can we improve on tubulin agents
-
Jackson JR, Patrick DR, Dar MM. Targeted anti-mitotic therapies: can we improve on tubulin agents. Nat Rev Cancer. 2007, 7:107-17.
-
(2007)
Nat Rev Cancer.
, vol.7
, pp. 107-117
-
-
Jackson, J.R.1
Patrick, D.R.2
Dar, M.M.3
et al4
-
36
-
-
33846470036
-
Lithium ions: a novel treatment for pheochromocytomas and paragangliomas
-
Kappes A, Vaccaro A, Kunnimalaiyaan M. Lithium ions: a novel treatment for pheochromocytomas and paragangliomas. Surgery. 2007, 141:161-5.
-
(2007)
Surgery.
, vol.141
, pp. 161-165
-
-
Kappes, A.1
Vaccaro, A.2
Kunnimalaiyaan, M.3
et al4
-
37
-
-
34547920351
-
Mutations in SIRT2 deacetylase which regulate enzymatic activity but not its interaction with HDAC6 and tubulin
-
Nahhas F, Dryden SC, Abrams J. Mutations in SIRT2 deacetylase which regulate enzymatic activity but not its interaction with HDAC6 and tubulin. Mol Cell Biochem. 2007, 303:221-330.
-
(2007)
Mol Cell Biochem.
, vol.303
, pp. 221-330
-
-
Nahhas, F.1
Dryden, S.C.2
Abrams, J.3
et al4
-
38
-
-
40049091449
-
CDK/GSK-3 inhibitors as therapeutic agents for parenchymal renal diseases
-
Obligado SH, Ibraghimov-Beskrovnaya O, Zuk A. CDK/GSK-3 inhibitors as therapeutic agents for parenchymal renal diseases. Kidney Int. 2008, 73:684-90.
-
(2008)
Kidney Int.
, vol.73
, pp. 684-690
-
-
Obligado, S.H.1
Ibraghimov-Beskrovnaya, O.2
Zuk, A.3
et al4
-
39
-
-
29644432626
-
Lithium stimulates proliferation in cultured thyrocytes by activating Wnt/beta-catenin signalling
-
Rao AS, Kremenevskaja N, Resch J. Lithium stimulates proliferation in cultured thyrocytes by activating Wnt/beta-catenin signalling. Eur J Endocrinol. 2007, 153:929-38.
-
(2007)
Eur J Endocrinol.
, vol.153
, pp. 929-938
-
-
Rao, A.S.1
Kremenevskaja, N.2
Resch, J.3
et al4
-
40
-
-
34547782316
-
Inhibition of GSK-3 beta activity attenuates proliferation of human colon cancer cells in rodents
-
Shakoori A, Mai W, Miyashita K. Inhibition of GSK-3 beta activity attenuates proliferation of human colon cancer cells in rodents. Cancer Sci. 2007, 98:1388-93.
-
(2007)
Cancer Sci.
, vol.98
, pp. 1388-1393
-
-
Shakoori, A.1
Mai, W.2
Miyashita, K.3
et al4
-
41
-
-
0032810903
-
Inhibition of cell proliferation by lithium is associated with interference in cdc2 activation
-
Smits VA, Essers MA, Loomans DS. Inhibition of cell proliferation by lithium is associated with interference in cdc2 activation. FEBS Lett. 1999, 457:23-7.
-
(1999)
FEBS Lett.
, vol.457
, pp. 23-27
-
-
Smits, V.A.1
Essers, M.A.2
Loomans, D.S.3
et al4
-
43
-
-
0037442990
-
A role for glycogen synthase kinase-3 in mitotic spindle dynamics and chromosome alignment
-
Wakefield JG, Stephens DJ, Tavare JM. A role for glycogen synthase kinase-3 in mitotic spindle dynamics and chromosome alignment. J Cell Sci. 2003, 116:637-46.
-
(2003)
J Cell Sci.
, vol.116
, pp. 637-646
-
-
Wakefield, J.G.1
Stephens, D.J.2
Tavare, J.M.3
-
44
-
-
34548397326
-
Cross-talk between the androgen receptor and the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer
-
Wang Y, Kreisberg JI, Ghosh PM. Cross-talk between the androgen receptor and the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer. Curr Cancer Drug Targets. 2007, 7:591-604.
-
(2007)
Curr Cancer Drug Targets.
, vol.7
, pp. 591-604
-
-
Wang, Y.1
Kreisberg, J.I.2
Ghosh, P.M.3
-
45
-
-
34547746398
-
Implication of the transcription factor E2F-1 in the modulation of neuronal apoptosis
-
Verdaguer E, Susana Gde A, Clemens A. Implication of the transcription factor E2F-1 in the modulation of neuronal apoptosis. Biomed Pharmacother. 2007, 61:390-9.
-
(2007)
Biomed Pharmacother.
, vol.61
, pp. 390-399
-
-
Verdaguer, E.1
Susana Gde, A.2
Clemens, A.3
et al4
-
46
-
-
33750885775
-
Molecular and biochemical features in Alzheimer's disease
-
Pallàs M, Camins A. Molecular and biochemical features in Alzheimer's disease. Curr Pharm Des. 2006, 12:4389-408.
-
(2006)
Curr Pharm Des.
, vol.12
, pp. 4389-4408
-
-
Pallàs, M.1
Camins, A.2
-
47
-
-
33748087835
-
Involvement of calpain activation in neurodegenerative processes
-
Camins A, Verdaguer E, Folch J. Involvement of calpain activation in neurodegenerative processes. CNS Drug Rev. 2006, 12:135-48.
-
(2006)
CNS Drug Rev.
, vol.12
, pp. 135-148
-
-
Camins, A.1
Verdaguer, E.2
Folch, J.3
et al4
-
48
-
-
41749088686
-
Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases
-
Nunomura A, Moreira PI, Lee HG. Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases. CNS Neurol Disord Drug Target. 2007, 6:411-23.
-
(2007)
CNS Neurol Disord Drug Target.
, vol.6
, pp. 411-423
-
-
Nunomura, A.1
Moreira, P.I.2
Lee, H.G.3
et al4
-
49
-
-
33947178563
-
Alzheimer disease, the two-hit hypothesis: an update
-
Zhu X, Lee HG, Perry G. Alzheimer disease, the two-hit hypothesis: an update. Biochim Biophys Acta. 2007, 1772:494-502.
-
(2007)
Biochim Biophys Acta.
, vol.1772
, pp. 494-502
-
-
Zhu, X.1
Lee, H.G.2
Perry, G.3
et al4
-
50
-
-
33645288896
-
The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target
-
Webber KM, Casadesus G, Zhu X. The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target. Curr Pharm Des. 2006, 12:691-7.
-
(2006)
Curr Pharm Des.
, vol.12
, pp. 691-697
-
-
Webber, K.M.1
Casadesus, G.2
Zhu, X.3
et al4
-
51
-
-
0034972923
-
Cdc2 phosphorylation of nucleolin demarcates mitotic stages and Alzheimer's disease pathology
-
Dranovsky A, Vincent I, Gregori L. Cdc2 phosphorylation of nucleolin demarcates mitotic stages and Alzheimer's disease pathology. Neurobiol Aging. 2001, 22:517-28.
-
(2001)
Neurobiol Aging.
, vol.22
, pp. 517-528
-
-
Dranovsky, A.1
Vincent, I.2
Gregori, L.3
et al4
-
52
-
-
28144439415
-
Cdh1-APC/C, cyclin B-Cdc2, and Alzheimer's disease pathology
-
Aulia S, Tang BL. Cdh1-APC/C, cyclin B-Cdc2, and Alzheimer's disease pathology. Biochem Biophys Res Commun. 2006, 339:1-6.
-
(2006)
Biochem Biophys Res Commun.
, vol.339
, pp. 1-6
-
-
Aulia, S.1
Tang, B.L.2
-
53
-
-
0037335443
-
The E2F-Cdc2 cell-cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons
-
Bonni A. The E2F-Cdc2 cell-cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons. J Neurosci. 2003, 23:1649-61.
-
(2003)
J Neurosci.
, vol.23
, pp. 1649-1661
-
-
Bonni, A.1
-
54
-
-
0036282745
-
Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery
-
Konishi Y, Lehtinen M, Donovan N. Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Mol Cell. 2002, 9:1005-16.
-
(2002)
Mol Cell.
, vol.9
, pp. 1005-1016
-
-
Konishi, Y.1
Lehtinen, M.2
Donovan, N.3
et al4
|