메뉴 건너뛰기




Volumn 5, Issue 1, 2010, Pages

Ciliary neurotrophic factor protects striatal neurons against excitotoxicity by enhancing glial glutamate uptake

Author keywords

[No Author keywords available]

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; GAMMA DEXTRO GLUTAMYLGLYCINE; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; QUINOLINIC ACID; ASPARTIC ACID; BENZYLOXYASPARTATE;

EID: 77649116866     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008550     Document Type: Article
Times cited : (36)

References (39)
  • 3
    • 0032815680 scopus 로고    scopus 로고
    • Replicating Huntington's disease phenotype in experimental animals
    • Brouillet E, Conde F, Beal MF, Hantraye P (1999) Replicating Huntington's disease phenotype in experimental animals. Prog Neurobiol 59(5): 427-468.
    • (1999) Prog Neurobiol , vol.59 , Issue.5 , pp. 427-468
    • Brouillet, E.1    Conde, F.2    Beal, M.F.3    Hantraye, P.4
  • 4
    • 34047100940 scopus 로고    scopus 로고
    • N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease
    • Fan MM, Raymond LA (2007) N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease. Prog Neurobiol 81(5-6): 272-293.
    • (2007) Prog Neurobiol , vol.81 , Issue.5-6 , pp. 272-293
    • Fan, M.M.1    Raymond, L.A.2
  • 5
    • 0029900762 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor protects striatal output neurons in an animal model of Huntington disease
    • Anderson KD, Panayotatos N, Corcoran TL, Lindsay RM, Wiegand SJ (1996) Ciliary neurotrophic factor protects striatal output neurons in an animal model of Huntington disease. Proc Natl Acad Sci U S A 93(14): 7346-7351.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , Issue.14 , pp. 7346-7351
    • Anderson, K.D.1    Panayotatos, N.2    Corcoran, T.L.3    Lindsay, R.M.4    Wiegand, S.J.5
  • 6
    • 0030906578 scopus 로고    scopus 로고
    • Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease
    • Emerich DF, Winn SR, Hantraye PM, Peschanski M, Chen EY, et al. (1997) Protective effect of encapsulated cells producing neurotrophic factor CNTF in a monkey model of Huntington's disease. Nature 386(6623): 395-399.
    • (1997) Nature , vol.386 , Issue.6623 , pp. 395-399
    • Emerich, D.F.1    Winn, S.R.2    Hantraye, P.M.3    Peschanski, M.4    Chen, E.Y.5
  • 7
    • 0034690615 scopus 로고    scopus 로고
    • Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease
    • Mittoux V, Joseph JM, Conde F, Palfi S, Dautry C, et al. (2000) Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease. Hum Gene Ther 11(8): 1177-1187.
    • (2000) Hum Gene Ther , vol.11 , Issue.8 , pp. 1177-1187
    • Mittoux, V.1    Joseph, J.M.2    Conde, F.3    Palfi, S.4    Dautry, C.5
  • 8
    • 5644295321 scopus 로고    scopus 로고
    • Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: Results of a phase I study
    • Bloch J, Bachoud-Levi AC, Deglon N, Lefaucheur JP, Winkel L, et al. (2004) Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study. Hum Gene Ther 15(10): 968-975.
    • (2004) Hum Gene Ther , vol.15 , Issue.10 , pp. 968-975
    • Bloch, J.1    Bachoud-Levi, A.C.2    Deglon, N.3    Lefaucheur, J.P.4    Winkel, L.5
  • 9
    • 0029058922 scopus 로고
    • A role for ciliary neurotrophic factor as an inducer of reactive gliosis, the glial response to central nervous system injury
    • Winter CG, Saotome Y, Levison SW, Hirsh D (1995) A role for ciliary neurotrophic factor as an inducer of reactive gliosis, the glial response to central nervous system injury. Proc Natl Acad Sci U S A 92(13): 5865-5869.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.13 , pp. 5865-5869
    • Winter, C.G.1    Saotome, Y.2    Levison, S.W.3    Hirsh, D.4
  • 10
    • 0030271473 scopus 로고    scopus 로고
    • Acute exposure to CNTF in vivo induces multiple components of reactive gliosis
    • Levison SW, Ducceschi MH, Young GM, Wood TL (1996) Acute exposure to CNTF in vivo induces multiple components of reactive gliosis. Exp Neurol 141(2): 256-268.
    • (1996) Exp Neurol , vol.141 , Issue.2 , pp. 256-268
    • Levison, S.W.1    Ducceschi, M.H.2    Young, G.M.3    Wood, T.L.4
  • 11
    • 0030874601 scopus 로고    scopus 로고
    • Phenotypic alteration of astrocytes induced by ciliary neurotrophic factor in the intact adult brain, As revealed by adenovirus-mediated gene transfer
    • Lisovoski F, Akli S, Peltekian E, Vigne E, Haase G, et al. (1997) Phenotypic alteration of astrocytes induced by ciliary neurotrophic factor in the intact adult brain, As revealed by adenovirus-mediated gene transfer. J Neurosci 17(19): 7228-7236.
    • (1997) J Neurosci , vol.17 , Issue.19 , pp. 7228-7236
    • Lisovoski, F.1    Akli, S.2    Peltekian, E.3    Vigne, E.4    Haase, G.5
  • 12
    • 33745261791 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor activates astrocytes, redistributes their glutamate transporters GLAST and GLT-1 to raft microdomains, and improves glutamate handling in vivo
    • Escartin C, Brouillet E, Gubellini P, Trioulier Y, Jacquard C, et al. (2006) Ciliary neurotrophic factor activates astrocytes, redistributes their glutamate transporters GLAST and GLT-1 to raft microdomains, and improves glutamate handling in vivo. J Neurosci 26(22): 5978-5989.
    • (2006) J Neurosci , vol.26 , Issue.22 , pp. 5978-5989
    • Escartin, C.1    Brouillet, E.2    Gubellini, P.3    Trioulier, Y.4    Jacquard, C.5
  • 13
    • 0035001341 scopus 로고    scopus 로고
    • Glutamate uptake
    • Danbolt NC (2001) Glutamate uptake. Prog Neurobiol 65(1): 1-105.
    • (2001) Prog Neurobiol , vol.65 , Issue.1 , pp. 1-105
    • Danbolt, N.C.1
  • 14
    • 34447128136 scopus 로고    scopus 로고
    • Activation of astrocytes by CNTF induces metabolic plasticity and increases resistance to metabolic insults
    • Escartin C, Pierre K, Colin A, Brouillet E, Delzescaux T, et al. (2007) Activation of astrocytes by CNTF induces metabolic plasticity and increases resistance to metabolic insults. J Neurosci 27(27): 7094-7104.
    • (2007) J Neurosci , vol.27 , Issue.27 , pp. 7094-7104
    • Escartin, C.1    Pierre, K.2    Colin, A.3    Brouillet, E.4    Delzescaux, T.5
  • 15
    • 0027486072 scopus 로고
    • Neuropharmacology of quinolinic and kynurenic acids
    • Stone TW (1993) Neuropharmacology of quinolinic and kynurenic acids. Pharmacol Rev 45(3): 309-379.
    • (1993) Pharmacol Rev , vol.45 , Issue.3 , pp. 309-379
    • Stone, T.W.1
  • 16
    • 0023876882 scopus 로고
    • Quinolinic acid effects on amino acid release from the rat cerebral cortex in vitro and in vivo
    • Connick JH, Stone TW (1988) Quinolinic acid effects on amino acid release from the rat cerebral cortex in vitro and in vivo. Br J Pharmacol 93(4): 868-876.
    • (1988) Br J Pharmacol , vol.93 , Issue.4 , pp. 868-876
    • Connick, J.H.1    Stone, T.W.2
  • 17
    • 34548363867 scopus 로고    scopus 로고
    • LNAME reverses quinolinic acid-induced toxicity in rat corticostriatal slices: Involvement of src family kinases
    • Mallozzi C, Martire A, Domenici MR, Metere A, Popoli P, et al. (2007) LNAME reverses quinolinic acid-induced toxicity in rat corticostriatal slices: Involvement of src family kinases. J Neurosci Res 85(12): 2770-2777.
    • (2007) J Neurosci Res , vol.85 , Issue.12 , pp. 2770-2777
    • Mallozzi, C.1    Martire, A.2    Domenici, M.R.3    Metere, A.4    Popoli, P.5
  • 18
    • 33749512169 scopus 로고    scopus 로고
    • The cannabinoid receptor agonist WIN 55,212-2 attenuates the effects induced by quinolinic acid in the rat striatum
    • Pintor A, Tebano MT, Martire A, Grieco R, Galluzzo M, et al. (2006) The cannabinoid receptor agonist WIN 55,212-2 attenuates the effects induced by quinolinic acid in the rat striatum. Neuropharmacology 51(5): 1004-1012.
    • (2006) Neuropharmacology , vol.51 , Issue.5 , pp. 1004-1012
    • Pintor, A.1    Tebano, M.T.2    Martire, A.3    Grieco, R.4    Galluzzo, M.5
  • 19
    • 0037199692 scopus 로고    scopus 로고
    • SCH 58261 differentially influences quinolinic acid-induced effects in striatal and in hippocampal slices
    • Tebano MT, Domenici MR, Popoli P (2002) SCH 58261 differentially influences quinolinic acid-induced effects in striatal and in hippocampal slices. Eur J Pharmacol 450(3): 253-257.
    • (2002) Eur J Pharmacol , vol.450 , Issue.3 , pp. 253-257
    • Tebano, M.T.1    Domenici, M.R.2    Popoli, P.3
  • 20
    • 0033083208 scopus 로고    scopus 로고
    • Variability of neurotransmitter concentration and nonsaturation of postsynaptic AMPA receptors at synapses in hippocampal cultures and slices
    • Liu G, Choi S, Tsien RW (1999) Variability of neurotransmitter concentration and nonsaturation of postsynaptic AMPA receptors at synapses in hippocampal cultures and slices. Neuron 22(2): 395-409.
    • (1999) Neuron , vol.22 , Issue.2 , pp. 395-409
    • Liu, G.1    Choi, S.2    Tsien, R.W.3
  • 21
    • 0035805092 scopus 로고    scopus 로고
    • Control of glutamate clearance and synaptic efficacy by glial coverage of neurons
    • Oliet SH, Piet R, Poulain DA (2001) Control of glutamate clearance and synaptic efficacy by glial coverage of neurons. Science 292(5518): 923-926.
    • (2001) Science , vol.292 , Issue.5518 , pp. 923-926
    • Oliet, S.H.1    Piet, R.2    Poulain, D.A.3
  • 22
    • 60149090184 scopus 로고    scopus 로고
    • Role of glutamate transporters in corticostriatal synaptic transmission
    • Beurrier C, Bonvento G, Kerkerian-Le GL, Gubellini P (2009) Role of glutamate transporters in corticostriatal synaptic transmission. Neuroscience 158(4): 1608-1615.
    • (2009) Neuroscience , vol.158 , Issue.4 , pp. 1608-1615
    • Beurrier, C.1    Bonvento, G.2    Kerkerian-Le, G.L.3    Gubellini, P.4
  • 23
    • 0029761786 scopus 로고    scopus 로고
    • Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease
    • Emerich DF, Lindner MD, Winn SR, Chen EY, Frydel BR, et al. (1996) Implants of encapsulated human CNTF-producing fibroblasts prevent behavioral deficits and striatal degeneration in a rodent model of Huntington's disease. J Neurosci 16(16): 5168-5181.
    • (1996) J Neurosci , vol.16 , Issue.16 , pp. 5168-5181
    • Emerich, D.F.1    Lindner, M.D.2    Winn, S.R.3    Chen, E.Y.4    Frydel, B.R.5
  • 24
    • 0036615771 scopus 로고    scopus 로고
    • Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration
    • Mittoux V, Ouary S, Monville C, Lisovoski F, Poyot T, et al. (2002) Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration. J Neurosci 22(11): 4478-4486.
    • (2002) J Neurosci , vol.22 , Issue.11 , pp. 4478-4486
    • Mittoux, V.1    Ouary, S.2    Monville, C.3    Lisovoski, F.4    Poyot, T.5
  • 25
    • 0034979217 scopus 로고    scopus 로고
    • Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease
    • Pereira de Almeida L, Zala D, Aebischer P, Deglon N (2001) Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease. Neurobiol Dis 8(3): 433-446.
    • (2001) Neurobiol Dis , vol.8 , Issue.3 , pp. 433-446
    • Pereira de Almeida, L.1    Zala, D.2    Aebischer, P.3    Deglon, N.4
  • 26
    • 0036522987 scopus 로고    scopus 로고
    • Blockade of striatal adenosine A2A receptor reduces, through a presynaptic mechanism, quinolinic acid-induced excitotoxicity: Possible relevance to neuroprotective interventions in neurodegenerative diseases of the striatum
    • Popoli P, Pintor A, Domenici MR, Frank C, Tebano MT, et al. (2002) Blockade of striatal adenosine A2A receptor reduces, through a presynaptic mechanism, quinolinic acid-induced excitotoxicity: possible relevance to neuroprotective interventions in neurodegenerative diseases of the striatum. J Neurosci 22(5): 1967-1975.
    • (2002) J Neurosci , vol.22 , Issue.5 , pp. 1967-1975
    • Popoli, P.1    Pintor, A.2    Domenici, M.R.3    Frank, C.4    Tebano, M.T.5
  • 27
    • 0035157216 scopus 로고    scopus 로고
    • The role of group I and group II metabotropic glutamate receptors in modulation of striatal NMDA and quinolinic acid toxicity
    • Orlando LR, Alsdorf SA, Penney JB Jr, Young AB (2001) The role of group I and group II metabotropic glutamate receptors in modulation of striatal NMDA and quinolinic acid toxicity. Exp Neurol 167(1): 196-204.
    • (2001) Exp Neurol , vol.167 , Issue.1 , pp. 196-204
    • Orlando, L.R.1    Alsdorf, S.A.2    Penney Jr, J.B.3    Young, A.B.4
  • 28
    • 0035117253 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor may activate mature astrocytes via binding with the leukemia inhibitory factor receptor
    • Monville C, Coulpier M, Conti L, De-Fraja C, Dreyfus P, et al. (2001) Ciliary neurotrophic factor may activate mature astrocytes via binding with the leukemia inhibitory factor receptor. Mol Cell Neurosci 17(2): 373-384.
    • (2001) Mol Cell Neurosci , vol.17 , Issue.2 , pp. 373-384
    • Monville, C.1    Coulpier, M.2    Conti, L.3    De-Fraja, C.4    Dreyfus, P.5
  • 29
    • 0031023029 scopus 로고    scopus 로고
    • Ciliary neurotrophic factor receptor alpha-immunoreactivity in the monkey central nervous system
    • Kordower JH, Yaping C, Maclennan AJ (1997) Ciliary neurotrophic factor receptor alpha-immunoreactivity in the monkey central nervous system. J Comp Neurol 377(3): 365-380.
    • (1997) J Comp Neurol , vol.377 , Issue.3 , pp. 365-380
    • Kordower, J.H.1    Yaping, C.2    Maclennan, A.J.3
  • 30
    • 0029150526 scopus 로고
    • Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons
    • Mattson MP, Lovell MA, Furukawa K, Markesbery WR (1995) Neurotrophic factors attenuate glutamate-induced accumulation of peroxides, elevation of intracellular Ca2+ concentration, and neurotoxicity and increase antioxidant enzyme activities in hippocampal neurons. J Neurochem 65(4): 1740-1751.
    • (1995) J Neurochem , vol.65 , Issue.4 , pp. 1740-1751
    • Mattson, M.P.1    Lovell, M.A.2    Furukawa, K.3    Markesbery, W.R.4
  • 31
    • 4544242247 scopus 로고    scopus 로고
    • Association of excitatory amino acid transporters, especially EAAT2, with cholesterol-rich lipid raft micro-domains: Importance for excitatory amino acid transporter localization and function
    • Butchbach ME, Tian G, Guo H, Lin CL (2004) Association of excitatory amino acid transporters, especially EAAT2, with cholesterol-rich lipid raft micro-domains: importance for excitatory amino acid transporter localization and function. J Biol Chem 279(33): 34388-34396.
    • (2004) J Biol Chem , vol.279 , Issue.33 , pp. 34388-34396
    • Butchbach, M.E.1    Tian, G.2    Guo, H.3    Lin, C.L.4
  • 32
    • 0029811226 scopus 로고    scopus 로고
    • Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease
    • Masliah E, Alford M, DeTeresa R, Mallory M, Hansen L (1996) Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease. Ann Neurol 40(5): 759-766.
    • (1996) Ann Neurol , vol.40 , Issue.5 , pp. 759-766
    • Masliah, E.1    Alford, M.2    DeTeresa, R.3    Mallory, M.4    Hansen, L.5
  • 33
    • 0033015919 scopus 로고    scopus 로고
    • Hippocampal GABA and glutamate transporter immunoreactivity in patients with temporal lobe epilepsy
    • Mathern GW, Mendoza D, Lozada A, Pretorius JK, Dehnes Y, et al. (1999) Hippocampal GABA and glutamate transporter immunoreactivity in patients with temporal lobe epilepsy. Neurology 52(3): 453-472.
    • (1999) Neurology , vol.52 , Issue.3 , pp. 453-472
    • Mathern, G.W.1    Mendoza, D.2    Lozada, A.3    Pretorius, J.K.4    Dehnes, Y.5
  • 34
    • 0030708576 scopus 로고    scopus 로고
    • Changes of NMDA receptor subunit (NR1, NR2B) and glutamate transporter (GLT1) mRNA expression in Huntington's disease - an in situ hybridization study
    • Arzberger T, Krampfl K, Leimgruber S, Weindl A (1997) Changes of NMDA receptor subunit (NR1, NR2B) and glutamate transporter (GLT1) mRNA expression in Huntington's disease - an in situ hybridization study. J Neuropathol Exp Neurol 56(4): 440-454.
    • (1997) J Neuropathol Exp Neurol , vol.56 , Issue.4 , pp. 440-454
    • Arzberger, T.1    Krampfl, K.2    Leimgruber, S.3    Weindl, A.4
  • 35
    • 0343052687 scopus 로고    scopus 로고
    • Continuous administration of the glutamate uptake inhibitor L-trans-pyrrolidine- 2,4-dicarboxylate produces striatal lesion
    • Lievens JC, Dutertre M, Forni C, Salin P, Kerkerian-Le GL (1997) Continuous administration of the glutamate uptake inhibitor L-trans-pyrrolidine- 2,4-dicarboxylate produces striatal lesion. Brain Res Mol Brain Res 50(1-2): 181-189.
    • (1997) Brain Res Mol Brain Res , vol.50 , Issue.1-2 , pp. 181-189
    • Lievens, J.C.1    Dutertre, M.2    Forni, C.3    Salin, P.4    Kerkerian-Le, G.L.5
  • 36
    • 0036345741 scopus 로고    scopus 로고
    • Impaired glutamate transport and glutamate-glutamine cycling: Downstream effects of the Huntington mutation
    • Behrens PF, Franz P, Woodman B, Lindenberg KS, Landwehrmeyer GB (2002) Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation. Brain 125(Pt 8): 1908-1922.
    • (2002) Brain , vol.125 , Issue.PART 8 , pp. 1908-1922
    • Behrens, P.F.1    Franz, P.2    Woodman, B.3    Lindenberg, K.S.4    Landwehrmeyer, G.B.5
  • 37
    • 0034255026 scopus 로고    scopus 로고
    • Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus
    • Hottinger AF, Azzouz M, Deglon N, Aebischer P, Zurn AD (2000) Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus. J Neurosci 20(15): 5587-5593.
    • (2000) J Neurosci , vol.20 , Issue.15 , pp. 5587-5593
    • Hottinger, A.F.1    Azzouz, M.2    Deglon, N.3    Aebischer, P.4    Zurn, A.D.5
  • 38
    • 0026567764 scopus 로고
    • A consideration of neural counting methods
    • Coggeshall RE (1992) A consideration of neural counting methods. Trends Neurosci 15(1): 9-13.
    • (1992) Trends Neurosci , vol.15 , Issue.1 , pp. 9-13
    • Coggeshall, R.E.1
  • 39
    • 0037101615 scopus 로고    scopus 로고
    • Enhanced inhibition of synaptic transmission by dopamine in the nucleus accumbens during behavioral sensitization to cocaine
    • Beurrier C, Malenka RC (2002) Enhanced inhibition of synaptic transmission by dopamine in the nucleus accumbens during behavioral sensitization to cocaine. J Neurosci 22(14): 5817-5822.
    • (2002) J Neurosci , vol.22 , Issue.14 , pp. 5817-5822
    • Beurrier, C.1    Malenka, R.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.